Lena Skrutl
skrutlnize.bsky.social
Lena Skrutl
@skrutlnize.bsky.social
PhD candidate at jagannathanlab.com @ETHZurich studying satellite DNA barcodes' role in #Meiosis by breaking up happy chromosome couples 💔. 'Squashing brains, collecting virgins & washing testes' are phrases I regularly use #Drosophila
🏳️‍🌈 🐈 🍕
Pinned
Also super happy to share our #Meiosis preprint! We show that satDNA mismatches disrupt meiotic pairing, especially at centromeres, leading to oocyte death. This highlights the critical role of satDNA in maintaining meiotic stability
👉 researchsquare.com/article/rs-5538025/v1 !

Jagannathanlab.com
Reposted by Lena Skrutl
self-awareness is such a scam bc now i can see all my problems AND i still have them? rude
February 22, 2025 at 6:14 PM
Reposted by Lena Skrutl
The fact of the matter is that Black, Indigenous, Latino/a, LGBTQ+, and other minorities groups in the US have worse health than white, cis, heterosexual people. Not studying the problem won't make the difference go away. Studying how and why it happens and making policies based on facts will. /fin
February 14, 2025 at 11:58 AM
Reposted by Lena Skrutl
Conservatives have pushed hard the idea that there is science corruption-- because they want to destroy science and universities.

There are some problems with some scientists. But the science system is still great. Letting conservative elites tear it down to enrich billionaires wld be a disaster.
February 14, 2025 at 4:46 PM
Reposted by Lena Skrutl
If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.
January 28, 2025 at 9:45 PM
Reposted by Lena Skrutl
Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi
January 17, 2025 at 10:39 AM
Reposted by Lena Skrutl
We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...
January 6, 2025 at 7:03 PM
Reposted by Lena Skrutl
This is not a drill, British Meiosis Meeting 2025 will be in Liverpool 🎉. Join us on 26-27 of March docs.google.com/forms/d/e/1F...
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva
January 16, 2025 at 7:21 AM
Also super happy to share our #Meiosis preprint! We show that satDNA mismatches disrupt meiotic pairing, especially at centromeres, leading to oocyte death. This highlights the critical role of satDNA in maintaining meiotic stability
👉 researchsquare.com/article/rs-5538025/v1 !

Jagannathanlab.com
January 16, 2025 at 3:31 PM
Thrilled to share our paper is out in @plosbiology.org! 🎉 We explore how satellite DNA organization is linked to transposon repression. A huge thanks to my amazing co-first author Ankita Chavan and all the collaborators who made this possible! 💕

jagannathanlab.com
#Proteomics

Check it out here 👇👇
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression
Pericentromeric heterochromatin clusters into nuclear foci known as chromocenters, the proteome of which remains largely unknown. This study uses quantitative mass spectrometry to characterize the chr...
plos.io
January 16, 2025 at 3:15 PM
Reposted by Lena Skrutl
Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi
January 16, 2025 at 1:13 PM