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singmolsci.bsky.social
UNSW Single Molecule Science
@singmolsci.bsky.social
1.5K followers 130 following 8 posts
Transforming medicine through research from a single-molecule perspective. Dept of Molecular Medicine at #UNSWSBMS @ UNSW.
Biophysics | microscopy | nanotech. sms.unsw.edu.au
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singmolsci.bsky.social
Come and work with us! 👇
ijayas.bsky.social Izzy Jayasinghe @ijayas.bsky.social · 23d
📣 We are hiring! An education-focused Lecturer or Senior Lecturer in Quantitative Biomedical or Biophysical sciences. It’s a chance to be a part of a team of single molecule /cellular biophysicists building a brand new undergraduate curriculum, here at UNSW in sunny Sydney. Happy to answer queries.
Lecturer / Senior Lecturer in Quantitative Biomedical Sciences (Education focused)
The incumbent will contribute to undergraduate teaching in biophysics or quantitative biomedical sciences within the School of Biomedical Sciences.
external-careers.jobs.unsw.edu.au
October 22, 2025 at 7:58 PM
Reposted by UNSW Single Molecule Science
ijayas.bsky.social
Privileged to join the ranks of EMBL Australia’s partner laboratories steering committee, representing @singmolsci.bsky.social, the EMBL Aus node in Single Molecule Science. Lots of new developments around the corner for this wonderful Medical & Life Sciences community in Australia.
September 22, 2025 at 1:02 PM
singmolsci.bsky.social
Well done to the team from Single Molecule Science who participated in the Science in the Swamp celebration of 2025 National Science Week at Centennial Park, Sydney. 'Microscopic Safari' was a fun journey over everything in the nano and micron scale on a sunny winter Sunday. ✨😎 🧪
August 18, 2025 at 9:23 AM
Reposted by UNSW Single Molecule Science
locusj.bsky.social
Our #AI #research @natcomms.nature.com uses #multiomics data integration concepts to fuse 4-channel imaging data into unlimitedly multiplexed image datasets via generative deep learning to interrogate complex cell biology, like #EMT. Multiplexing made easy! rdcu.be/emtBc @singmolsci.bsky.social
Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data
Nature Communications - Gunawan et al. propose an Extensible Immunofluorescence (ExIF) strategy that integrates distinct 4-plex image panels from routine fluorescence microscopy into multiplexed...
rdcu.be
May 20, 2025 at 8:44 AM
singmolsci.bsky.social
Fantastic to see this short film about A/Prof Lawrence Lee who is a Group Leader in UNSW Single Molecule Science and the founding CEO of the exciting startup, SWAN Genomics 🧬🔬
arccoesb.bsky.social ARC Centre of Excellence in Synthetic Biology @arccoesb.bsky.social · May 15
🚀 Meet Our Centre Startups: SWAN Genomics with Associate Professor Lawrence Lee

SWAN Genomics is changing the way we sequence #DNA with a new approach that goes beyond today’s short-read and long-read methods. #Startup #SyntheticBiology #Biotechnology

youtu.be/WCT3sA2-jtY?...
Swan Genomics
YouTube video by ARC Centre of Excellence in Synthetic Biology
youtu.be
May 17, 2025 at 11:09 PM
Reposted by UNSW Single Molecule Science
ijayas.bsky.social
Hello #AcademicBsky hivemind! Is there anyone out here (preferably from Australia / nearby) who uses FIB or BE lithography at submicron resolution on materials like quartz, and might be interested in collaborating with us on a cool new project?

Happy to take recommendations. 🧪 🔬
May 1, 2025 at 10:24 PM
Reposted by UNSW Single Molecule Science
katepoole.bsky.social
A beautifully elegant study from Vaish and Leeba and team looking at mitochondrial volume regulation using cleverly designed and fabricated chambers to track fission yeast divisions over time
vaishananth.bsky.social Vaishnavi Ananthanarayanan (She/Her) @vaishananth.bsky.social · Apr 9
How is mitochondrial volume maintained across successive generations of dividing cells? In our new preprint, we show how fission yeast cells use mitochondrial activity to control division timing and maintain mitochondrial homeostasis! (1/n)

📖 www.biorxiv.org/content/10.1...
April 9, 2025 at 5:51 AM
Reposted by UNSW Single Molecule Science
vaishananth.bsky.social
How is mitochondrial volume maintained across successive generations of dividing cells? In our new preprint, we show how fission yeast cells use mitochondrial activity to control division timing and maintain mitochondrial homeostasis! (1/n)

📖 www.biorxiv.org/content/10.1...
April 9, 2025 at 2:53 AM
singmolsci.bsky.social
Aaaand that’s a wrap at Asia Pacific Microscopy Congress 2025 in sunny Brisbane, attended by a big team from Single Molecule Science. Lots of exciting new 🔬 tools and translation in biomedical investigations. @ijayas.bsky.social @arindam92.bsky.social
Group photo of eight colleagues representing the dept, standing in front of the conference mural Some colleagues sitting around a dinner table A conference speaker standing at a lectern podium Arindam Ghosh being introduced to the symposium by Liz Hinde.
February 7, 2025 at 10:19 AM
singmolsci.bsky.social
We’ve had a single molecule festival here today at the @UNSW SciFest yesterday. Our corner of the exhibition featuring light sensing robots 🤖, reef cleaning super hero bacteria 🦸🏾‍♂️ , miniature microscopes, when killer T cells. A wonderful team effort and a busy evening for Team Molecular Medicine.
A group photo of the Molecular Medicine (Single Molecule Sciences) team. In front, a table with some objects, including a miniature microscope. In the background, a large tv screen with vibrant images of cells and molecules. A conversation between Upasana from Molecular Medicine and a little girl and her mum. Upasana is leaning over a table with a miniature microscope. Some team members of Molecular Medicine standing in front of a colourful big tv screen and talking to some of the SciFest visitors A father and daughter speaking with Dr Jon and pinning the superhero capes on the art board game of bacteria deployed to save the Great Barrier Reef.
August 16, 2024 at 10:13 PM
Reposted by UNSW Single Molecule Science
ijayas.bsky.social
Final week for applications for up to 2 postdoc posts in advanced biomedical (super-resolution) microscopy with my team in Sydney, based at @singmolsci.bsky.social. The post is especially suited for ECRs interested in single molecule imaging, &/or image analysis. International applicants welcome 🧪
Post-Doctoral Fellow in Advanced Biomedical Microscopy
UNSW Department of Molecular Medicine seeks an enthusiastic researcher in super-resolution microscopy to develop novel super resolution methods and leverage these techniques to study cellular architec...
external-careers.jobs.unsw.edu.au
February 6, 2024 at 11:23 AM
Reposted by UNSW Single Molecule Science
molecmachines.bsky.social
The #HIV capsid mimics host chaperones to gain access into the nucleus, solving a long-standing mystery – David Jacques' team published in Nature.
@singmolsci.bsky.social #UNSWSBMS
🔗 nature.com/articles/s41...
🎨: Jon Berengut
Artistic depiction of the HIV capsid disguised as a host chaperone protein
January 25, 2024 at 12:27 AM
Reposted by UNSW Single Molecule Science
molecmachines.bsky.social
🚨preprint @biorxivpreprint.bsky.social
We use #SingleMolecule🔬to see how a capsid-targeting antiviral (lenacapavir) hacks assembly of the HIV capsid, which normally protects the #HIV genome. Now also with real-time visualization of the drug breaking open the capsid. www.biorxiv.org/content/10.1...
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 28, 2023 at 5:50 AM
Reposted by UNSW Single Molecule Science
molecmachines.bsky.social
We've still taking applications to join our team @singmolsci.bsky.social. Now closing 10Dec2023
🔗 external-careers.jobs.unsw.edu.au/cw/en/job/52...
molecmachines.bsky.social Molecular Machines & Structural Virology Group @molecmachines.bsky.social · Nov 8
🚨Join us at UNSW Sydney!
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
Ariel photo of UNSW's main campus located near close to beaches
November 28, 2023 at 5:55 AM
singmolsci.bsky.social
Being able to work with a research & cultural leader like Izzy @ijayas.bsky.social is an opportunity you won’t want to miss.
ijayas.bsky.social Izzy Jayasinghe @ijayas.bsky.social · Nov 21
If there is anybody on Bluesky with an interest in working towards a PhD with a vibrant and inclusive group of people, we have a funded project available through @singmolsci.bsky.social in UNSW, Sydney, to do some advanced single molecule & electron 🔬. Please pass on to any students you may know. 🧪
Molecular scale mapping of intracellular signalling nanodomains and giant channels in the heart
www.unsw.edu.au
November 21, 2023 at 11:21 PM
Reposted by UNSW Single Molecule Science
vaishananth.bsky.social
Thanks for highlighting our (@polybiotique.bsky.social) report and its coverage by @dyanilewis.bsky.social, Izzy. As we mention in our report, fixing this will require clearly earmarked resources, and importantly, the will and strong commitment to equity from the leadership in Indian academia.
ijayas.bsky.social Izzy Jayasinghe @ijayas.bsky.social · Nov 15
A shocking description 👇🏾 of how women are being let down by scientific research communities in India. This is of course only mirroring many of the trends that we know exist everywhere else too. The 📊 showing conferences where women are outnumbered or excluded entirely leaves one absolutely appalled.
November 16, 2023 at 8:15 AM
Reposted by UNSW Single Molecule Science
ijayas.bsky.social
Latest paper from our team on variations in cellular staining with 14 different fluorescent dye esters when combined with expansion microscopy. Strategic deployment of these dyes with expansion 🔬 can not only provide EM-like images, but also highlight different sets of cellular organelles. 🧪
Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion ...
Amine-reactive esters of aromatic fluorescent dyes are emerging as imaging probes for nondescript staining of cellular and tissue architectures. We characterised the staining patterns of 14 fluorescen...
pubs.rsc.org
November 13, 2023 at 7:51 PM
Reposted by UNSW Single Molecule Science
ijayas.bsky.social
A few things that I've needed to get off my chest for some time now. 🧪 🌋
Remembering the role of luck and privilege in academic achievement
This week I woke up to the announcement by my alma mater — The University of Auckland — of its 2023 cohort of ’40 under 40’ that listed me…
medium.com
November 3, 2023 at 12:16 PM
singmolsci.bsky.social
Towards inclusive and sustainable scientific meetings
davislab.bsky.social Felicity Davis @davislab.bsky.social · Nov 10
Our thoughts on how to make conferences more inclusive and sustainable - with @vaishananth.bsky.social and a great international team. Check it out here: rdcu.be/dqHEM
November 10, 2023 at 3:10 AM
Reposted by UNSW Single Molecule Science
molecmachines.bsky.social
🚨Join us at UNSW Sydney!
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
Ariel photo of UNSW's main campus located near close to beaches
November 8, 2023 at 6:11 AM