Molecular Machines & Structural Virology Group
@molecmachines.bsky.social
We develop fluorescence imaging approaches to visualise the dynamics of self-assembly processes at the single-molecule level, esp. host-pathogen interactions. UNSW Sydney. Posts by group members. https://www.sms.unsw.edu.au/our-research/molecular-machines
Super cool to see @science.org named anti-HIV drug lenacapavir as Breakthrough of the Year. 🧪This breakthrough is underpinned by a wealth of basic research. Our contribution is to show how the drug cracks the protective HIV capsid 👇https://doi.org/10.7554/elife.83605
December 13, 2024 at 11:17 AM
Super cool to see @science.org named anti-HIV drug lenacapavir as Breakthrough of the Year. 🧪This breakthrough is underpinned by a wealth of basic research. Our contribution is to show how the drug cracks the protective HIV capsid 👇https://doi.org/10.7554/elife.83605
The #HIV capsid mimics host chaperones to gain access into the nucleus, solving a long-standing mystery – David Jacques' team published in Nature.
@singmolsci.bsky.social #UNSWSBMS
🔗 nature.com/articles/s41...
🎨: Jon Berengut
@singmolsci.bsky.social #UNSWSBMS
🔗 nature.com/articles/s41...
🎨: Jon Berengut
January 25, 2024 at 12:27 AM
The #HIV capsid mimics host chaperones to gain access into the nucleus, solving a long-standing mystery – David Jacques' team published in Nature.
@singmolsci.bsky.social #UNSWSBMS
🔗 nature.com/articles/s41...
🎨: Jon Berengut
@singmolsci.bsky.social #UNSWSBMS
🔗 nature.com/articles/s41...
🎨: Jon Berengut
We've still taking applications to join our team @singmolsci.bsky.social. Now closing 10Dec2023
🔗 external-careers.jobs.unsw.edu.au/cw/en/job/52...
🔗 external-careers.jobs.unsw.edu.au/cw/en/job/52...
🚨Join us at UNSW Sydney!
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
November 28, 2023 at 5:55 AM
We've still taking applications to join our team @singmolsci.bsky.social. Now closing 10Dec2023
🔗 external-careers.jobs.unsw.edu.au/cw/en/job/52...
🔗 external-careers.jobs.unsw.edu.au/cw/en/job/52...
🚨preprint @biorxivpreprint.bsky.social
We use #SingleMolecule🔬to see how a capsid-targeting antiviral (lenacapavir) hacks assembly of the HIV capsid, which normally protects the #HIV genome. Now also with real-time visualization of the drug breaking open the capsid. www.biorxiv.org/content/10.1...
We use #SingleMolecule🔬to see how a capsid-targeting antiviral (lenacapavir) hacks assembly of the HIV capsid, which normally protects the #HIV genome. Now also with real-time visualization of the drug breaking open the capsid. www.biorxiv.org/content/10.1...
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 28, 2023 at 5:50 AM
🚨preprint @biorxivpreprint.bsky.social
We use #SingleMolecule🔬to see how a capsid-targeting antiviral (lenacapavir) hacks assembly of the HIV capsid, which normally protects the #HIV genome. Now also with real-time visualization of the drug breaking open the capsid. www.biorxiv.org/content/10.1...
We use #SingleMolecule🔬to see how a capsid-targeting antiviral (lenacapavir) hacks assembly of the HIV capsid, which normally protects the #HIV genome. Now also with real-time visualization of the drug breaking open the capsid. www.biorxiv.org/content/10.1...
🚨Join us at UNSW Sydney!
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
November 8, 2023 at 6:11 AM
🚨Join us at UNSW Sydney!
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics
We're searching for a postdoc to join our team to investigate dynamics of host-pathogen interactions🦠.
#SingleMolecule #microscopy🔬
Apply by 26Nov2023. Please share 🔗https://external-careers.jobs.unsw.edu.au/cw/en/job/520570/post-doctoral-fellow-hostpathogen-biophysics