Sergiu P. Pasca
@sergiuppasca.bsky.social
Professor at Stanford & Director of Stanford Brain Organogenesis
Lab: https://pascalab.org
Center: http://www.brainorganogenesis.org
TED: https://go.ted.com/6WJy
Instagram: https://www.instagram.com/sergiu.p.pasca/
Lab: https://pascalab.org
Center: http://www.brainorganogenesis.org
TED: https://go.ted.com/6WJy
Instagram: https://www.instagram.com/sergiu.p.pasca/
An amazing group of scientists, philosophers, legal scholars, ethicists, policy makers, patient advocates, funders and trainees convened at Asilomar for one of the most stimulating meetings I have had the privilege to organize, focused on the ethics of research with neural #organoids & #assembloids
November 14, 2025 at 6:56 PM
An amazing group of scientists, philosophers, legal scholars, ethicists, policy makers, patient advocates, funders and trainees convened at Asilomar for one of the most stimulating meetings I have had the privilege to organize, focused on the ethics of research with neural #organoids & #assembloids
Last day of discussions at this thought-provoking conference at Asilomar on the ethics and societal implications of neural organoids and assembloids, which I co-organized with @hankgreely.bsky.social
November 13, 2025 at 1:14 AM
Last day of discussions at this thought-provoking conference at Asilomar on the ethics and societal implications of neural organoids and assembloids, which I co-organized with @hankgreely.bsky.social
This week, we published in @science.org an article outlining the current ethical and societal implications of research involving human neural #organoids and #assembloids, their transplantation, and highlighted potential next steps.
November 7, 2025 at 12:12 PM
This week, we published in @science.org an article outlining the current ethical and societal implications of research involving human neural #organoids and #assembloids, their transplantation, and highlighted potential next steps.
October 23, 2025 at 10:40 PM
By popular demand — the next edition of our hands-on @Stanford @BrOrganogenesis course is coming in 2026!
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
October 16, 2025 at 5:29 PM
By popular demand — the next edition of our hands-on @Stanford @BrOrganogenesis course is coming in 2026!
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
Less than two weeks left to register for the inaugural conference on Assembloids & Complex Cell-Cell Interactions at @cshlnews.bsky.social
Check out the topics and amazing lineup of speakers!
Check out the topics and amazing lineup of speakers!
October 3, 2025 at 8:04 AM
Less than two weeks left to register for the inaugural conference on Assembloids & Complex Cell-Cell Interactions at @cshlnews.bsky.social
Check out the topics and amazing lineup of speakers!
Check out the topics and amazing lineup of speakers!
A bittersweet day as another postdoc leaves to start an independent lab at St Jude’s Children Hospital.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
October 1, 2025 at 6:18 PM
A bittersweet day as another postdoc leaves to start an independent lab at St Jude’s Children Hospital.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
Invited speakers here:
September 12, 2025 at 6:28 PM
Invited speakers here:
One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
September 12, 2025 at 6:28 PM
One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research!
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
August 21, 2025 at 5:42 PM
Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research!
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
Consider joining us at Stanford as a postdoctoral fellow!
If you have a published paper or a preprint, will graduate in the next period, and are excited to work in California, email me your CV and a brief statement of your research interests and trajectory by the end of August.
If you have a published paper or a preprint, will graduate in the next period, and are excited to work in California, email me your CV and a brief statement of your research interests and trajectory by the end of August.
August 13, 2025 at 10:09 PM
Consider joining us at Stanford as a postdoctoral fellow!
If you have a published paper or a preprint, will graduate in the next period, and are excited to work in California, email me your CV and a brief statement of your research interests and trajectory by the end of August.
If you have a published paper or a preprint, will graduate in the next period, and are excited to work in California, email me your CV and a brief statement of your research interests and trajectory by the end of August.
Our recent overview of human stem cell models for studying neuropsychiatric disorders (including their limitations and future directions) is now openly available @annualreviews.bsky.social of Neuroscience
With the great @rebeccalevymdphd.bsky.social
With the great @rebeccalevymdphd.bsky.social
July 19, 2025 at 7:52 PM
Our recent overview of human stem cell models for studying neuropsychiatric disorders (including their limitations and future directions) is now openly available @annualreviews.bsky.social of Neuroscience
With the great @rebeccalevymdphd.bsky.social
With the great @rebeccalevymdphd.bsky.social
Our latest work is out today in @science.org: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development.
Work led by Massimo Onesto with Neal Amin in the lab
Work led by Massimo Onesto with Neal Amin in the lab
July 17, 2025 at 8:07 PM
Our latest work is out today in @science.org: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development.
Work led by Massimo Onesto with Neal Amin in the lab
Work led by Massimo Onesto with Neal Amin in the lab
Sharing today the latest from our lab, just published in Nature Biomedical Engineering.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
July 11, 2025 at 4:46 PM
Sharing today the latest from our lab, just published in Nature Biomedical Engineering.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
Strong interest already in the upcoming Asilomar meeting on the ethical and societal implications of human neural #organoids, #assembloids, and their transplantation.
Just 10 days left to apply—details at the link below.
Just 10 days left to apply—details at the link below.
July 11, 2025 at 1:06 AM
Strong interest already in the upcoming Asilomar meeting on the ethical and societal implications of human neural #organoids, #assembloids, and their transplantation.
Just 10 days left to apply—details at the link below.
Just 10 days left to apply—details at the link below.
Excited to announce that applications are open for the Asilomar meeting on The Ethical and Societal Implications of Neural Organoids, Assembloids, and Their Transplantation!
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
July 8, 2025 at 5:32 PM
Excited to announce that applications are open for the Asilomar meeting on The Ethical and Societal Implications of Neural Organoids, Assembloids, and Their Transplantation!
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
Thrilled to introduce the newest PhD from the lab—Dr. Massimo Onesto—who successfully defended his thesis @stanfordmedicine.bsky.social.
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
June 20, 2025 at 10:59 PM
Thrilled to introduce the newest PhD from the lab—Dr. Massimo Onesto—who successfully defended his thesis @stanfordmedicine.bsky.social.
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
Looking forward to a thought-provoking session today at @isscr.org in Hong Kong—discussing emerging ethical questions around neural #organoids, #assembloids, and their transplantation. Join us at 2 PM in Hall 3G.
June 12, 2025 at 3:07 AM
Looking forward to a thought-provoking session today at @isscr.org in Hong Kong—discussing emerging ethical questions around neural #organoids, #assembloids, and their transplantation. Join us at 2 PM in Hall 3G.
Over the past couple of weeks, several asked if I could share the individual slides summarizing our recently published framework in @nature.com on designing experiments with #organoids, #assembloids, and transplantation. Here they are—6 slides capturing the key takeaways👇
June 2, 2025 at 4:34 PM
Over the past couple of weeks, several asked if I could share the individual slides summarizing our recently published framework in @nature.com on designing experiments with #organoids, #assembloids, and transplantation. Here they are—6 slides capturing the key takeaways👇
Time to celebrate two more postdocs from the Pasca lab who are departing this month to start their own groups– at Johns Hopkins and in Shanghai.
Warmest congratulations Xiao & Jin, and all the best!
Traditional selfie at our lab party with a now classical #assembloid cake (not shown).
Warmest congratulations Xiao & Jin, and all the best!
Traditional selfie at our lab party with a now classical #assembloid cake (not shown).
May 20, 2025 at 11:12 AM
Time to celebrate two more postdocs from the Pasca lab who are departing this month to start their own groups– at Johns Hopkins and in Shanghai.
Warmest congratulations Xiao & Jin, and all the best!
Traditional selfie at our lab party with a now classical #assembloid cake (not shown).
Warmest congratulations Xiao & Jin, and all the best!
Traditional selfie at our lab party with a now classical #assembloid cake (not shown).
This is a bittersweet week as we say goodbye to a phenomenal postdoc in the lab— Xiangling Meng—who is leaving to start her own independent lab at Baylor College of Medicine.
May 14, 2025 at 4:57 AM
This is a bittersweet week as we say goodbye to a phenomenal postdoc in the lab— Xiangling Meng—who is leaving to start her own independent lab at Baylor College of Medicine.
This week we welcome on campus 2025 class of students for our hands-on Stanford Brain Organogenesis course.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
May 7, 2025 at 4:46 PM
This week we welcome on campus 2025 class of students for our hands-on Stanford Brain Organogenesis course.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
What human experimental models do we currently have to study brain disorders—and where do they fall short?
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
May 6, 2025 at 7:06 PM
What human experimental models do we currently have to study brain disorders—and where do they fall short?
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
The deadline for the @cshlmeetings course on #autism spectrum disorder is approaching. This was my entry into the field more than 15 years ago. While this will be my final year co-organizing it, I am looking forward to the stimulating discussions in the beautiful Banbury Center. More details 👇
April 17, 2025 at 8:36 PM
The deadline for the @cshlmeetings course on #autism spectrum disorder is approaching. This was my entry into the field more than 15 years ago. While this will be my final year co-organizing it, I am looking forward to the stimulating discussions in the beautiful Banbury Center. More details 👇