Sérgia Velho
Sérgia Velho
@sergiavelho.bsky.social
Researcher at @i3S_UPorto, Portugal. Interested in the biology of mutant KRAS cancers and in the characterization of cellular and molecular cancer ecosystems.
Reposted by Sérgia Velho
𝗘𝗫𝗧𝗘𝗡𝗗𝗘𝗗 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗨𝗕𝗠𝗜𝗦𝗦𝗜𝗢𝗡 𝗗𝗘𝗔𝗗𝗟𝗜𝗡𝗘❗
The SINAL meeting gathers researchers in #Biomedicine focusing on key issues in cell biology and signal transduction.
𝗔𝗯𝘀𝘁𝗿𝗮𝗰𝘁 𝘀𝘂𝗯𝗺𝗶𝘀𝘀𝗶𝗼𝗻⏰𝟭𝟱𝗝𝘂𝗹
Registrations⏰early until 24Jul, standard until 4Sep
lnkd.in/dHDnC8Xj
#i3Sevents
July 11, 2025 at 12:04 PM
Reposted by Sérgia Velho
#ResearchHighlight🚨
In a recent study published in
@naturecomms.bsky.social
Chen et al. now demonstrate that the cholesterol biosynthesis protein CYP51A1 suppresses alkaliptosis induced by the opioid analgesic JTC801.
📖 ⬇️
Blocking cholesterol biosynthesis to clean out cancer - Nature Reviews Cancer
The mechanisms of how pH-dependent cell death, alkaliptosis, is regulated are incompletely understood. Chen et al. now demonstrate that the cholesterol biosynthesis protein CYP51A1 suppresses alkaliptosis induced by the opioid analgesic JTC801.
bit.ly
April 14, 2025 at 2:31 PM
Reposted by Sérgia Velho
Learn about cellular #phylodynamics approaches at the EMBO Workshop "Lineage tracing: Dynamics, cellular memory and somatic evolution" in Sant Feliu de Guixols, Spain, 18–21 Sep

Abstract submission/Registration deadline: 2/30 Jun

meetings.embo.org/event/25-lin...
#EMBOlineageTracing #EMBOevents 🧪
Lineage tracing: Dynamics, cellular memory, and somatic evolution
Recent advances in high-resolution lineage tracing technologies and single-cell genomics are allowing researchers to quantify cell state dynamics at unprecedented scales. Across cancer and immunity, …
meetings.embo.org
April 11, 2025 at 6:18 AM
Reposted by Sérgia Velho
Crick researchers have found that certain aggressive lung cancer cells can develop their own electric network, similar to the body’s nervous system.

This can allow tumour cells to go ‘off grid,’ making them harder to treat.
www.crick.ac.uk/news/2025-02...
Lung cancer cells can go ‘off grid’
Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their own electric network, like that seen in the body’s nervous system. This un...
www.crick.ac.uk
February 12, 2025 at 4:35 PM
Reposted by Sérgia Velho
Out today in Nature: "The Human Cell Atlas"! In my News and Views, I compare the cell atlas to early naturalists creating an atlas of South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution.
www.nature.com/articles/d41...
November 20, 2024 at 5:07 PM