Jonathon Sens
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sensjonathon.bsky.social
Jonathon Sens
@sensjonathon.bsky.social
18 followers 40 following 1 posts
Neuroimmunologist studying all things glial and lymphocyte interactions in OUD and AD — @KiralyLab
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Reposted by Jonathon Sens
cellpress.bsky.social
"The microbiota extends the reproductive lifespan of mice by safeguarding the ovarian reserve" www.cell.com/cell-host-mi...

@cp-cellhostmicrobe.bsky.social
@pittdeptofmed.bsky.social Eldin Jašarević & colleagues
Munyoki et al. demonstrate that gut microbiota extend the female reproductive lifespan by safeguarding the ovarian reserve. Germ-free mice undergo accelerated primordial follicle loss and reduced reproductive capacity that are restored upon post-natal colonization. Microbial SCFAs contribute to protection, and dietary fiber supplementation maintains oocyte quality under obesogenic diets.
September 25, 2025 at 8:03 PM
Reposted by Jonathon Sens
danis1337.bsky.social
Super excited to announce our new paper (and tool) spearheaded by
@hasansiam.xyz
! CAFE (cell analyzer for flow experiments) is a user-friendly web app to analyze flow cytometry data. No coding required! Check out the paper academic.oup.com/bioinformati... 🔬💻
Fig. 2. Profiling of Human PBMCs Reveals Distinct Immune Subpopulations and Marker Expression Patterns. (a) UMAP plots showing selected marker expression intensities across all cells in the UMAP space to highlight lineage-specific marker distribution. (b) Dot plot of all marker expression across all identified PBMC cell types. Dendrogram highlighted distinct marker-based groupings. (c) UMAP visualization showing 16 distinct clusters with annotated cell types including Naive CD4 and CD8 T cells, central memory CD4 and CD8 T cells (Tcm), effector memory CD8 T cells (Tem), terminally differentiated effector memory CD8 T cells (Temra), mucosal-associated invariant (MAIT) T cells, classical monocytes (cMO), intermediate monocytes (iMO), B cells, NK cells, gamma delta (γδ) T cells (Tgd), conventional dendritic cell (cDC) and plasmacytoid dendritic cell (pDC).
April 25, 2025 at 4:47 PM
sensjonathon.bsky.social
Excited to explore ways to leverage the immune system with world-class preclinical and clinical researchers! Please attend if time allows!!
wakeforestcfar.bsky.social Wake Forest Center for Addiction Research @wakeforestcfar.bsky.social · Apr 22
Join us Tuesday, April 29 from 12–1 PM for the first Bridging the Divide seminar, hosted by CFAR. Dr. Erin Barnes and PhD student Jonathon Sens will discuss immune and infectious processes in opioid use disorder. Teams link here: shorturl.at/7nRFi
April 23, 2025 at 1:07 AM
Reposted by Jonathon Sens
zhaonaa.bsky.social
Excited to share our findings on how APOE genotype impacts cell responses to AD using human brain snRNAseq. Huge thanks to the team for all the hard work! @drneurochic.bsky.social @mayoclinic.org @cp-neuron.bsky.social
March 20, 2025 at 1:38 AM
Reposted by Jonathon Sens
wakeforestcfar.bsky.social
Our next CFAR 2024 Research Round-Up post features work from the Kiraly Lab examining clinical and preclinical evidence for gut microbiome mechanisms in substance use disorders.
February 11, 2025 at 6:32 PM