Na Zhao
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zhaonaa.bsky.social
Na Zhao
@zhaonaa.bsky.social
150 followers 120 following 1 posts
Associate Professor | Department of Neuroscience | Mayo Clinic
https://www.mayo.edu/research/labs/neurobiology-alzheimers-disease-related-dementias/overview
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zhaonaa.bsky.social
Excited to share our findings on how APOE genotype impacts cell responses to AD using human brain snRNAseq. Huge thanks to the team for all the hard work! @drneurochic.bsky.social @mayoclinic.org @cp-neuron.bsky.social
March 20, 2025 at 1:38 AM
Reposted by Na Zhao
cp-neuron.bsky.social
APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease
Using single-nucleus RNA sequencing on post-mortem brains from control subjects and Alzheimer’s disease patients, Li et al. revealed APOE-genotype-specific molecular alterations across distinct brain cell types associated with AD. This study offers a…
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March 19, 2025 at 6:36 PM