Seeger Lab
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seegerlab.bsky.social
Seeger Lab
@seegerlab.bsky.social
Lab of Prof. Markus A. Seeger, @UZH_en, posts by group members; great admirers of membrane proteins, nanobodies, sybodies, structural biology and microbiology
Here you'll find everything a structure-function aficionado might hope for:
✅ Crystallography 💎
✅ Cryo-EM 🔬
✅ Nanobodies 🦙
✅ Mutational analysis 🧬
✅ Molecular dynamics simulations 🖥️
March 13, 2025 at 8:28 PM
Check out this nicely written News & Views article by Parjit Kaur about our paper!

nature.com/articles/s4158…
Deep dive into a drug pump
Nature Chemical Biology - Major hurdles remain in understanding the mechanisms of multidrug resistance (MDR) protein efflux. A new study uses deep mutational scanning of a bacterial MDR protein to...
www.nature.com
March 13, 2025 at 8:27 PM
Many thanks to our collaborators @Barandunlab, @kai_ehrenbolger for their great effort to determine the cryoEM structure of EfrCD💪💪☺️
March 13, 2025 at 8:27 PM
For their project - IBD NanoBiotics - the team engineered gut microbiota member E. coli Nissle 1917 to secrete anti-inflammatory nanobodies which dampen inflammation in GI tract of IBD patients. Supervised by Kenny from @MartinJinek lab, Jenna and @f_ackle from our lab
March 13, 2025 at 8:27 PM
...and here are the heros of the review, Michèle Sorgenfrei and Lea Huber-Hürlimann. The PI is very proud!!
March 13, 2025 at 8:26 PM