Seeger Lab
@seegerlab.bsky.social
Lab of Prof. Markus A. Seeger, @UZH_en, posts by group members; great admirers of membrane proteins, nanobodies, sybodies, structural biology and microbiology
Congrats to Dr. Sille Remm for winning the 1st special prize from the President of Estonian Academy of Science "for the most elegant work" in the Estonian National Student Science Competition!🥳👏 So proud of you!
March 13, 2025 at 8:27 PM
Congrats to Dr. Sille Remm for winning the 1st special prize from the President of Estonian Academy of Science "for the most elegant work" in the Estonian National Student Science Competition!🥳👏 So proud of you!
Proud to see our DMS paper out in @nchembio after going through a productive review process🥳EfrCD's drug efflux activity profile determined for >1400 single variants. Identified single mutations that convert the exporter into a drug-specific ABC importer!
nature.com/articles/s4158…
nature.com/articles/s4158…
March 13, 2025 at 8:27 PM
Proud to see our DMS paper out in @nchembio after going through a productive review process🥳EfrCD's drug efflux activity profile determined for >1400 single variants. Identified single mutations that convert the exporter into a drug-specific ABC importer!
nature.com/articles/s4158…
nature.com/articles/s4158…
Congrats to the @uzh iGEM team for winning the best therapeutics project🥇 and best new basic part awards🥇 and for getting into the top 10 among the 350 projects at this year's @iGEM Jamboree in Paris! We're happy for all your achievements! 🤩👏It was fun to host you in our lab!
March 13, 2025 at 8:27 PM
Congrats to the @uzh iGEM team for winning the best therapeutics project🥇 and best new basic part awards🥇 and for getting into the top 10 among the 350 projects at this year's @iGEM Jamboree in Paris! We're happy for all your achievements! 🤩👏It was fun to host you in our lab!
new group photo... PARKOUR!🤸🏻♀️💨
March 13, 2025 at 8:27 PM
new group photo... PARKOUR!🤸🏻♀️💨
The climax of a 5 year collaborative project with the @enricabordignon lab: spin-labelled nanobodies to probe the conformational space of MsbA in intact cells published in @ScienceAdvances. Structures by @MoellerGroup and MD simulations by Lars Schäfer lab
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
March 13, 2025 at 8:27 PM
The climax of a 5 year collaborative project with the @enricabordignon lab: spin-labelled nanobodies to probe the conformational space of MsbA in intact cells published in @ScienceAdvances. Structures by @MoellerGroup and MD simulations by Lars Schäfer lab
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
Congrats to Sille Remm for successfully defending her PhD thesis!🥳👩🎓 You did very well biting through this tough project! We're so proud of you!☺️☺️
March 13, 2025 at 8:27 PM
Congrats to Sille Remm for successfully defending her PhD thesis!🥳👩🎓 You did very well biting through this tough project! We're so proud of you!☺️☺️
The temperature dropped by a few degrees yesterday, so we decided to have a raclette on our rooftop🧀😋
March 13, 2025 at 8:27 PM
The temperature dropped by a few degrees yesterday, so we decided to have a raclette on our rooftop🧀😋
...and here are the heros of the review, Michèle Sorgenfrei and Lea Huber-Hürlimann. The PI is very proud!!
March 13, 2025 at 8:26 PM
...and here are the heros of the review, Michèle Sorgenfrei and Lea Huber-Hürlimann. The PI is very proud!!
We're happy to announce that our latest review about biomolecules capturing live bacteria from clinical samples is out on @TrendsBiochem !!🥳🥳
doi.org/10.1016/j.tibs…
doi.org/10.1016/j.tibs…
March 13, 2025 at 8:26 PM
We're happy to announce that our latest review about biomolecules capturing live bacteria from clinical samples is out on @TrendsBiochem !!🥳🥳
doi.org/10.1016/j.tibs…
doi.org/10.1016/j.tibs…
On a special mission to join a delegation of the Round Table Antibiotics to talk with members of the Swiss parliament about the urgent need to increase the federal budget to fight #AMR 💊🦠
March 13, 2025 at 8:26 PM
On a special mission to join a delegation of the Round Table Antibiotics to talk with members of the Swiss parliament about the urgent need to increase the federal budget to fight #AMR 💊🦠
📢Our rapid response to the COVID-19 pandemic finally in peer-reviewed form @emboreports in collaboration with Philippe Plattet, @CPaulino_ @MembraneEnzymo1 🥳
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.…
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.…
March 13, 2025 at 8:26 PM
📢Our rapid response to the COVID-19 pandemic finally in peer-reviewed form @emboreports in collaboration with Philippe Plattet, @CPaulino_ @MembraneEnzymo1 🥳
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.…
„Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance“
doi.org/10.15252/embr.…
Preparing E.coli produced avocado smoothie🥑 for the afternoon apéro... or is it GFP-tagged protein?😜
March 13, 2025 at 8:26 PM
Preparing E.coli produced avocado smoothie🥑 for the afternoon apéro... or is it GFP-tagged protein?😜
The heros of this review, Sille Remm and Jennifer Earp, with a very proud PI
March 13, 2025 at 8:26 PM
The heros of this review, Sille Remm and Jennifer Earp, with a very proud PI
We're excited that our latest review on the multifaceted characters of mycobacterial drug efflux pumps is out in @FEMSmicro 🥳🥳
Great collaboration with @ThomasD57648102 and @vdartois1🤝#mycobacteria #tuberculosis #drugefflux
doi.org/10.1093/femsre…
Great collaboration with @ThomasD57648102 and @vdartois1🤝#mycobacteria #tuberculosis #drugefflux
doi.org/10.1093/femsre…
March 13, 2025 at 8:26 PM
We're excited that our latest review on the multifaceted characters of mycobacterial drug efflux pumps is out in @FEMSmicro 🥳🥳
Great collaboration with @ThomasD57648102 and @vdartois1🤝#mycobacteria #tuberculosis #drugefflux
doi.org/10.1093/femsre…
Great collaboration with @ThomasD57648102 and @vdartois1🤝#mycobacteria #tuberculosis #drugefflux
doi.org/10.1093/femsre…
Our latest preprint is out🥳We performed DMS on EfrCD to determine the drug efflux activity profile of 1539 single variants!
Many interesting findings🔎, amongst which, that single mutations (!) can convert the exporter into a drug-specific ABC importer!
doi.org/10.1101/2021.1…
Many interesting findings🔎, amongst which, that single mutations (!) can convert the exporter into a drug-specific ABC importer!
doi.org/10.1101/2021.1…
March 13, 2025 at 8:25 PM
Our latest preprint is out🥳We performed DMS on EfrCD to determine the drug efflux activity profile of 1539 single variants!
Many interesting findings🔎, amongst which, that single mutations (!) can convert the exporter into a drug-specific ABC importer!
doi.org/10.1101/2021.1…
Many interesting findings🔎, amongst which, that single mutations (!) can convert the exporter into a drug-specific ABC importer!
doi.org/10.1101/2021.1…
Congrats to @CamiloPerez_BZ and team!🔥👏 We're happy to have contributed to the success of this great work! Once again #sybodies enabled the structure determination of a small membrane protein.
t.co/9brN71a2pp biorxiv.org/content/10.110…
t.co/9brN71a2pp biorxiv.org/content/10.110…
March 13, 2025 at 8:25 PM
Congrats to @CamiloPerez_BZ and team!🔥👏 We're happy to have contributed to the success of this great work! Once again #sybodies enabled the structure determination of a small membrane protein.
t.co/9brN71a2pp biorxiv.org/content/10.110…
t.co/9brN71a2pp biorxiv.org/content/10.110…
Congrats to @DenekaDawid, Sonja Rutz and @MartaSawicka6 from the Dutzler lab for this fantastic piece of work!🥳👏 Great to see that sybodies helped to shed light on the mechanism of volume-regulated channels!
nature.com/articles/s4146…
nature.com/articles/s4146…
March 13, 2025 at 8:25 PM
Congrats to @DenekaDawid, Sonja Rutz and @MartaSawicka6 from the Dutzler lab for this fantastic piece of work!🥳👏 Great to see that sybodies helped to shed light on the mechanism of volume-regulated channels!
nature.com/articles/s4146…
nature.com/articles/s4146…
Congrats to Michèle for winning the Poster prize at the #Nanobodies21 conference! The PI is proud of you😁🥳
March 13, 2025 at 8:24 PM
Congrats to Michèle for winning the Poster prize at the #Nanobodies21 conference! The PI is proud of you😁🥳
Hope all the in-person and virtual attendees of the #Nanobodies21 conference have enjoyed Justin Walter‘s talk about the Nestlink Technology 😁🍰 Justin, you made us proud!
March 13, 2025 at 8:24 PM
Hope all the in-person and virtual attendees of the #Nanobodies21 conference have enjoyed Justin Walter‘s talk about the Nestlink Technology 😁🍰 Justin, you made us proud!
On our way to the #nanobodies21 conference in Brussels 🇧🇪🦙
March 13, 2025 at 8:24 PM
On our way to the #nanobodies21 conference in Brussels 🇧🇪🦙
📢Don't miss it: Markus is giving a talk at the @EMBO workshop titled "Recent Advances in Structural Biology of Membrane Proteins" #EMBOMPsRegistration deadline is the 1st of November!
embl.org/about/info/cou…
embl.org/about/info/cou…
March 13, 2025 at 8:24 PM
📢Don't miss it: Markus is giving a talk at the @EMBO workshop titled "Recent Advances in Structural Biology of Membrane Proteins" #EMBOMPsRegistration deadline is the 1st of November!
embl.org/about/info/cou…
embl.org/about/info/cou…
The Seeger lab is fully vaccinated💉 We did an antibody test 2 weeks after the 2nd shot and…nice response💪🏽😄 Fun fact: a bispecific fusion of our sybody pair is coated on the control lane!
March 13, 2025 at 8:24 PM
The Seeger lab is fully vaccinated💉 We did an antibody test 2 weeks after the 2nd shot and…nice response💪🏽😄 Fun fact: a bispecific fusion of our sybody pair is coated on the control lane!
Here it is - the new logo of the lab!😀
March 13, 2025 at 8:24 PM
Here it is - the new logo of the lab!😀
🎓🧑🎓Congrats to Gianmarco for successfully defending his PhD thesis! Great achievements over the last years!💪💪 We're very proud of him!🥳
March 13, 2025 at 8:24 PM
🎓🧑🎓Congrats to Gianmarco for successfully defending his PhD thesis! Great achievements over the last years!💪💪 We're very proud of him!🥳