Sebastian Triesch
@sebtriesch.bsky.social
Plant Scientist in Bioinformatics. Loving Genomics, Machine Learning and Synthetic Biology
Reposted by Sebastian Triesch
Helixer: a tool for ab initio gene annotation with broad taxonomic coverage. @usadellab.bsky.social @apmweber.bsky.social @weberlab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
December 3, 2025 at 5:35 PM
Helixer: a tool for ab initio gene annotation with broad taxonomic coverage. @usadellab.bsky.social @apmweber.bsky.social @weberlab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sebastian Triesch
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
November 26, 2025 at 6:00 AM
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Reposted by Sebastian Triesch
🌿 RESEARCH 🌿
Single-nucleus RNAseq reveals bundle sheath cell-specific photorespiration pathways in Moricandia arvensis, incl ammonium assimilation & redox regulation, highlighting metabolic compartmentalization in C3–C4 photosynthesis – Triesch et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Single-nucleus RNAseq reveals bundle sheath cell-specific photorespiration pathways in Moricandia arvensis, incl ammonium assimilation & redox regulation, highlighting metabolic compartmentalization in C3–C4 photosynthesis – Triesch et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
November 11, 2025 at 1:00 PM
🌿 RESEARCH 🌿
Single-nucleus RNAseq reveals bundle sheath cell-specific photorespiration pathways in Moricandia arvensis, incl ammonium assimilation & redox regulation, highlighting metabolic compartmentalization in C3–C4 photosynthesis – Triesch et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Single-nucleus RNAseq reveals bundle sheath cell-specific photorespiration pathways in Moricandia arvensis, incl ammonium assimilation & redox regulation, highlighting metabolic compartmentalization in C3–C4 photosynthesis – Triesch et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Reposted by Sebastian Triesch
Speaker introduction. Let’s introduce our seventh speaker JANA PETER from the @hhu.de @ceplas.bsky.social who will give an inspiring talk at our #soapboxscience event in 1 week!
📅Saturday, June 28
📍Rheinpromenade, Düsseldorf
#womeninstem #womeninscience #soapboxscience
📅Saturday, June 28
📍Rheinpromenade, Düsseldorf
#womeninstem #womeninscience #soapboxscience
June 19, 2025 at 8:12 AM
Speaker introduction. Let’s introduce our seventh speaker JANA PETER from the @hhu.de @ceplas.bsky.social who will give an inspiring talk at our #soapboxscience event in 1 week!
📅Saturday, June 28
📍Rheinpromenade, Düsseldorf
#womeninstem #womeninscience #soapboxscience
📅Saturday, June 28
📍Rheinpromenade, Düsseldorf
#womeninstem #womeninscience #soapboxscience
Reposted by Sebastian Triesch
Our latest paper is out in its final form in @theplantcell.bsky.social
We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context.
Read the full paper at: doi.org/10.1093/plce...
We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context.
Read the full paper at: doi.org/10.1093/plce...
June 17, 2025 at 5:10 PM
Our latest paper is out in its final form in @theplantcell.bsky.social
We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context.
Read the full paper at: doi.org/10.1093/plce...
We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context.
Read the full paper at: doi.org/10.1093/plce...