Sebastian Bitzenhofer
@sebbitzenhofer.bsky.social
Reposted by Sebastian Bitzenhofer
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
October 2, 2025 at 3:46 PM
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
Reposted by Sebastian Bitzenhofer
Reposted by Sebastian Bitzenhofer
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
September 10, 2025 at 3:08 PM
Reposted by Sebastian Bitzenhofer
Thanks to the support of the F.R.S. - FNRS, I’m hiring two postdocs to help kickstart the lab. Informal inquiries are welcome via socials or email.
More about the two postdoc positions and how to apply: www.chinilab.com/opportunitie...
RT for visibility are greatly appreciated! 🙏
More about the two postdoc positions and how to apply: www.chinilab.com/opportunitie...
RT for visibility are greatly appreciated! 🙏
Chini Lab
Chini Lab at GIGA–ULiège. We study how neural activity emerges in early development from a systems neuroscience perspective.
www.chinilab.com
August 27, 2025 at 8:53 AM
Thanks to the support of the F.R.S. - FNRS, I’m hiring two postdocs to help kickstart the lab. Informal inquiries are welcome via socials or email.
More about the two postdoc positions and how to apply: www.chinilab.com/opportunitie...
RT for visibility are greatly appreciated! 🙏
More about the two postdoc positions and how to apply: www.chinilab.com/opportunitie...
RT for visibility are greatly appreciated! 🙏
Reposted by Sebastian Bitzenhofer
I am thrilled to share that this winter I will be starting my lab in the GIGA Institute of @universitedeliege.bsky.social!
The lab will study early brain development at the intersection of systems and computational neuroscience.
🌐 You can find out more on the lab website: www.chinilab.com
1/2
The lab will study early brain development at the intersection of systems and computational neuroscience.
🌐 You can find out more on the lab website: www.chinilab.com
1/2
Chini Lab
Chini Lab at GIGA–ULiège. We study how neural activity emerges in early development from a systems neuroscience perspective.
www.chinilab.com
August 27, 2025 at 8:51 AM
I am thrilled to share that this winter I will be starting my lab in the GIGA Institute of @universitedeliege.bsky.social!
The lab will study early brain development at the intersection of systems and computational neuroscience.
🌐 You can find out more on the lab website: www.chinilab.com
1/2
The lab will study early brain development at the intersection of systems and computational neuroscience.
🌐 You can find out more on the lab website: www.chinilab.com
1/2
Reposted by Sebastian Bitzenhofer
🚨 We are looking for 2 PhD students! 🧠🐸👃
Join the Manzini Lab @jlugiessen.bsky.social to explore the olfactory system in #aquatic #vertebrates.
We mainly use #amphibians, combining:
🔬 Imaging
👩🔬 Cell biology
🐝 Behavior
👉 bit.ly/neurophd
🌍 bit.ly/manzinilab
Please share!
#PhD #neuroscience #job
Join the Manzini Lab @jlugiessen.bsky.social to explore the olfactory system in #aquatic #vertebrates.
We mainly use #amphibians, combining:
🔬 Imaging
👩🔬 Cell biology
🐝 Behavior
👉 bit.ly/neurophd
🌍 bit.ly/manzinilab
Please share!
#PhD #neuroscience #job
August 22, 2025 at 8:15 AM
🚨 We are looking for 2 PhD students! 🧠🐸👃
Join the Manzini Lab @jlugiessen.bsky.social to explore the olfactory system in #aquatic #vertebrates.
We mainly use #amphibians, combining:
🔬 Imaging
👩🔬 Cell biology
🐝 Behavior
👉 bit.ly/neurophd
🌍 bit.ly/manzinilab
Please share!
#PhD #neuroscience #job
Join the Manzini Lab @jlugiessen.bsky.social to explore the olfactory system in #aquatic #vertebrates.
We mainly use #amphibians, combining:
🔬 Imaging
👩🔬 Cell biology
🐝 Behavior
👉 bit.ly/neurophd
🌍 bit.ly/manzinilab
Please share!
#PhD #neuroscience #job
Reposted by Sebastian Bitzenhofer
New preprint is out! We present iSTTC, a robust method for estimating intrinsic neural timescales (ITs) from single-unit activity. It’s accurate, stable, and works even when data is sparse.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
iSTTC: a robust method for accurate estimation of intrinsic neural timescales from single-unit recordings
Intrinsic neural timescales (ITs) are an emerging measure of how neural circuits integrate information over time. ITs are dynamically regulated by behavioral context and cognitive demands, making them...
doi.org
August 5, 2025 at 8:27 AM
New preprint is out! We present iSTTC, a robust method for estimating intrinsic neural timescales (ITs) from single-unit activity. It’s accurate, stable, and works even when data is sparse.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Sebastian Bitzenhofer
1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social
@wellcometrust.bsky.social
@wellcometrust.bsky.social
A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the
late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α
partners with ERRγ and Mef2c to ...
www.cell.com
July 16, 2025 at 7:59 AM
1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social
@wellcometrust.bsky.social
@wellcometrust.bsky.social
Reposted by Sebastian Bitzenhofer
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
www.science.org
June 26, 2025 at 6:06 PM
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
Reposted by Sebastian Bitzenhofer
Our new paper is out in Science.
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
Cholinergic feedback for modality- and context-specific modulation of sensory representations
The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...
www.science.org
June 20, 2025 at 3:32 PM
Our new paper is out in Science.
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
A while back, we noticed unexpectedly high Disc1 expression in the developing olfactory bulb. We found that disrupting Disc1 alters early OB activity, which plays a key role in shaping the maturation of memory-related brain circuits.
www.jneurosci.org/content/45/2...
www.jneurosci.org/content/45/2...
Developmental Olfactory Dysfunction and Abnormal Odor Memory in Immune-Challenged Disc1+/− Mice
Neuronal activity in the olfactory bulb (OB) drives coordinated activity in the hippocampal–prefrontal network during early development. Inhibiting OB output in neonatal mice disrupts functional devel...
www.jneurosci.org
June 18, 2025 at 9:13 PM
A while back, we noticed unexpectedly high Disc1 expression in the developing olfactory bulb. We found that disrupting Disc1 alters early OB activity, which plays a key role in shaping the maturation of memory-related brain circuits.
www.jneurosci.org/content/45/2...
www.jneurosci.org/content/45/2...
Reposted by Sebastian Bitzenhofer
I'd like to make a list of PhD programs that (1) are in Europe (which does include the UK); (2) offer opportunities in systems neuroscience; and obviously (3) pay a stipend. Please share and/or respond to add your suggestions?
June 17, 2025 at 5:25 PM
I'd like to make a list of PhD programs that (1) are in Europe (which does include the UK); (2) offer opportunities in systems neuroscience; and obviously (3) pay a stipend. Please share and/or respond to add your suggestions?
Reposted by Sebastian Bitzenhofer
I signed up to post this week for @realscientists.de (in German 😬), so let's see how that goes 🙂
[Admin] Rhythmen im Gehirn - Bitte begrüßt Natalie Schaworonkow auf dem Kanal!
realscientistsde.blogspot.com/2025/06/rhyt...
realscientistsde.blogspot.com/2025/06/rhyt...
Rhythmen im Gehirn - Natalie Schaworonkow ist jetzt bei Real Scientists DE!
Diese Woche freuen wir uns auf Natalie Schaworonkow . Natalie (@ nschawor.bsky.social ) hat Kognitionswissenschaften und Computational Neur...
realscientistsde.blogspot.com
June 16, 2025 at 9:29 AM
I signed up to post this week for @realscientists.de (in German 😬), so let's see how that goes 🙂
Reposted by Sebastian Bitzenhofer
Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
June 6, 2025 at 9:34 AM
Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
Reposted by Sebastian Bitzenhofer
1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
May 27, 2025 at 7:49 AM
1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
Reposted by Sebastian Bitzenhofer
Success in academia often has more to do with luck, patronage and the job market than “hard work”.
Good academics acknowledge this.
I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.
Good academics acknowledge this.
I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.
May 21, 2025 at 7:16 AM
Success in academia often has more to do with luck, patronage and the job market than “hard work”.
Good academics acknowledge this.
I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.
Good academics acknowledge this.
I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.
Reposted by Sebastian Bitzenhofer
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
May 18, 2025 at 8:41 AM
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Reposted by Sebastian Bitzenhofer
Tomorrow morning, March 29th at 11:30 am, check out Symposium 31 at #NWG2025 @neurowissg.bsky.social organized by MODOLFOR member Tobias Ackels @tobiasackels.bsky.social
March 28, 2025 at 3:11 PM
Tomorrow morning, March 29th at 11:30 am, check out Symposium 31 at #NWG2025 @neurowissg.bsky.social organized by MODOLFOR member Tobias Ackels @tobiasackels.bsky.social
Reposted by Sebastian Bitzenhofer
I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.ce... 1/16 🧵
March 1, 2025 at 1:14 PM
I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.ce... 1/16 🧵
Reposted by Sebastian Bitzenhofer
Very happy to announce the "Paris Circuit Dynamics Conference 2025: Hippocampal–Cortical Circuits: From structure to computation", on 28 - 29 April 2025 at the Paris Brain Institute.
You are welcome to register and join us!
www.paris-circuits.eu
You are welcome to register and join us!
www.paris-circuits.eu
Paris Circuit Dynamics
This two-day conference will bring together leading experts from the Paris region and abroad to discuss the dynamics and neural coding in hippocampal and cortical circuits.
The program will focus on ...
www.paris-circuits.eu
February 19, 2025 at 5:01 PM
Very happy to announce the "Paris Circuit Dynamics Conference 2025: Hippocampal–Cortical Circuits: From structure to computation", on 28 - 29 April 2025 at the Paris Brain Institute.
You are welcome to register and join us!
www.paris-circuits.eu
You are welcome to register and join us!
www.paris-circuits.eu