@sci-illustrator.bsky.social
Reposted
I am thrilled to share with the world a new preprint, spearheaded by the truly amazing Jose Reyes in partnership with the Lowe lab. The paper sheds light on benign to malignant transition in PDAC, uncovering roles of plasticity, tissue remodeling and P53. -> www.biorxiv.org/content/10.1...
Oncogenic and tumor-suppressive forces converge on a progenitor-orchestrated niche to shape early tumorigenesis
The transition from benign to malignant growth is a pivotal yet poorly understood step in cancer progression that marks the shift from a pathologically inert condition to a clinically lethal disease. ...
www.biorxiv.org
July 3, 2025 at 1:12 PM
I am thrilled to share with the world a new preprint, spearheaded by the truly amazing Jose Reyes in partnership with the Lowe lab. The paper sheds light on benign to malignant transition in PDAC, uncovering roles of plasticity, tissue remodeling and P53. -> www.biorxiv.org/content/10.1...
Reposted
Almeida et al. show how F-box genes in C. elegans and zebrafish have fused with transposon-derived domains, contributing to functional and regulatory novelty for thermotolerance and fertility.
🔗 doi.org/10.1093/molbev/msaf097
#evolbio #TEsky
@miskalab.bsky.social
🔗 doi.org/10.1093/molbev/msaf097
#evolbio #TEsky
@miskalab.bsky.social
Transposable Elements Drive Regulatory and Functional Innovation of F-box Genes
Abstract. Protein domains of transposable elements (TEs) and viruses increase the protein diversity of host genomes by recombining with other protein domai
doi.org
May 12, 2025 at 1:58 PM
Almeida et al. show how F-box genes in C. elegans and zebrafish have fused with transposon-derived domains, contributing to functional and regulatory novelty for thermotolerance and fertility.
🔗 doi.org/10.1093/molbev/msaf097
#evolbio #TEsky
@miskalab.bsky.social
🔗 doi.org/10.1093/molbev/msaf097
#evolbio #TEsky
@miskalab.bsky.social
Reposted
Multiple recent studies, including 3 impressive natural experiments, consistently show a link between Shingles vaccines and reduced dementia. This week a nationwide S Korea study added a reduction of cardiovascular events
My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...
My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...
May 11, 2025 at 9:27 PM
Multiple recent studies, including 3 impressive natural experiments, consistently show a link between Shingles vaccines and reduced dementia. This week a nationwide S Korea study added a reduction of cardiovascular events
My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...
My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...