Sauer Lab
@sauer-lab.bsky.social
Congratulations Arindam and welcome back to Würzburg!
Happy to share that I will be starting my independent research career as a Research Group Leader at the German Cancer Research Center (DKFZ). Starting from January 2026, my group will be based at DKFZ National Center for Tumor Diseases (NCT WERA), Würzburg, Germany.
November 11, 2025 at 1:56 PM
Congratulations Arindam and welcome back to Würzburg!
🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
August 19, 2025 at 3:32 PM
🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
Reposted by Sauer Lab
Welcome to the youngSMLMS, a pre-SMLMS event for students, PhDs & PostDocs!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
June 17, 2025 at 3:54 PM
Welcome to the youngSMLMS, a pre-SMLMS event for students, PhDs & PostDocs!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
Reposted by Sauer Lab
Fully Funded PhD Scholarship in Centrosome Biology in the lab of Prof Ciaran Morrison: www.findaphd.com/phds/project...
Fully Funded PhD Scholarship in Centrosome Biology at University of Galway on FindAPhD.com
PhD Project - Fully Funded PhD Scholarship in Centrosome Biology at University of Galway, listed on FindAPhD.com
www.findaphd.com
April 25, 2025 at 2:49 PM
Fully Funded PhD Scholarship in Centrosome Biology in the lab of Prof Ciaran Morrison: www.findaphd.com/phds/project...
Amazing, congratulations!
How it started: About eight years ago Bob Tjian ("Tij") and I sat in the back of cab in San Francisco and discussed the crazy idea of using live-cell single-molecule tracking for high-throughput drug screening.
How it's going:
How it's going:
March 29, 2025 at 8:03 AM
Amazing, congratulations!
Reposted by Sauer Lab
Look what's happening at the French Embassy in Washington DC.
March 4, 2025 at 9:05 PM
Look what's happening at the French Embassy in Washington DC.
Reposted by Sauer Lab
Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
February 12, 2025 at 10:38 AM
Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Reposted by Sauer Lab
An excellent review about fluorescence labeling strategies by @beliulab.bsky.social Gerti Beliu and colleagues from Würzburg University - highly recommended reading for everybody interested in fluorescence microscopy!
Online now! Fluorescent labeling strategies for molecular bioimaging. Marcel Streit, Made Budiarta, Marvin Jungblut, and Gerti Beliu. www.cell.com/biophysrepor...
Fluorescent labeling strategies for molecular bioimaging
Super-resolution microscopy (SRM) has transformed biological imaging by circumventing
the diffraction limit of light and enabling the visualization of cellular structures
and processes at the molecula...
www.cell.com
February 14, 2025 at 5:21 PM
An excellent review about fluorescence labeling strategies by @beliulab.bsky.social Gerti Beliu and colleagues from Würzburg University - highly recommended reading for everybody interested in fluorescence microscopy!
🆕 Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy!
▶️ pubs.acs.org/doi/10.1021/...
▶️ pubs.acs.org/doi/10.1021/...
Functionalized Docetaxel Probes for Refined Visualization of Mitotic Spindles by Expansion Microscopy
Visualizing the ultrastructure of mitotic spindles, the macromolecular machines that segregate chromosomes during mitosis, by fluorescence imaging remains challenging. Here we introduce an azido- and ...
pubs.acs.org
February 12, 2025 at 12:49 PM
🆕 Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy!
▶️ pubs.acs.org/doi/10.1021/...
▶️ pubs.acs.org/doi/10.1021/...
Reposted by Sauer Lab
SAVE THE DATE 👇
#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org
#Bordeaux, 6-9 Oct 2025
@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social
#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org
#Bordeaux, 6-9 Oct 2025
@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social
February 7, 2025 at 8:22 AM
SAVE THE DATE 👇
#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org
#Bordeaux, 6-9 Oct 2025
@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social
#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org
#Bordeaux, 6-9 Oct 2025
@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social
Reposted by Sauer Lab
NIH-supported research saves lives: here are two "poster" human beings to prove it.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
February 10, 2025 at 4:51 PM
NIH-supported research saves lives: here are two "poster" human beings to prove it.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
Reposted by Sauer Lab
Delighted to launch our activities on Bluesky with this great news: Our researchers @sauer-lab.bsky.social show in @science.org, how therapeutic #antibodies interact with B cells – thanks to an innovative method of super-resolution microscopy. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...
➡️ www.uni-wuerzburg.de/en/news-and-...
January 10, 2025 at 11:04 AM
Delighted to launch our activities on Bluesky with this great news: Our researchers @sauer-lab.bsky.social show in @science.org, how therapeutic #antibodies interact with B cells – thanks to an innovative method of super-resolution microscopy. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...
➡️ www.uni-wuerzburg.de/en/news-and-...
🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
January 10, 2025 at 9:00 AM
🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
Reposted by Sauer Lab
Super happy to see the manuscript of my former PhD student and close friend Arindam Ghosh, @arindam92.bsky.social, and the Markus Sauer lab, @sauer-lab.bsky.social, being pblished in Science: www.science.org/doi/10.1126/...
Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy
Elucidating the interaction between membrane proteins and antibodies requires whole-cell imaging at high spatiotemporal resolution. Lattice light-sheet (LLS) microscopy offers fast volumetric imaging ...
www.science.org
January 10, 2025 at 6:55 AM
Super happy to see the manuscript of my former PhD student and close friend Arindam Ghosh, @arindam92.bsky.social, and the Markus Sauer lab, @sauer-lab.bsky.social, being pblished in Science: www.science.org/doi/10.1126/...
Well-deserved Luke
Gregorio Weber is a giant in our field, and I am deeply honored to receive this award in his name. I want to acknowledge all my collaborators over the years—especially @dyerfulchymist.bsky.social—and the place that made everything possible: @hhmijanelia.bsky.social
December 5, 2024 at 5:22 PM
Well-deserved Luke
Reposted by Sauer Lab
Happy to see my MSCA project with @jbneuro.bsky.social lab available on @biorxiv-neursci.bsky.social
We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!
We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!
December 2, 2024 at 6:22 PM
Happy to see my MSCA project with @jbneuro.bsky.social lab available on @biorxiv-neursci.bsky.social
We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!
We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!