Sanghyeon Park
@sapark95.bsky.social
Reposted by Sanghyeon Park
The most math equations written on a whiteboard by a clinician I've seen - yet amazingly well delivered to a broad audience!
S. Urbut's talk @broadinstitute.org A Practical Primer on Bayesian Statistics youtube.com/watch?v=jcFS...
@mgbresearch.bsky.social @harvardmed.bsky.social
S. Urbut's talk @broadinstitute.org A Practical Primer on Bayesian Statistics youtube.com/watch?v=jcFS...
@mgbresearch.bsky.social @harvardmed.bsky.social
MPG Primer: A Practical Primer on Bayesian Statistics (2025)
YouTube video by Broad Institute
youtube.com
May 6, 2025 at 2:58 PM
The most math equations written on a whiteboard by a clinician I've seen - yet amazingly well delivered to a broad audience!
S. Urbut's talk @broadinstitute.org A Practical Primer on Bayesian Statistics youtube.com/watch?v=jcFS...
@mgbresearch.bsky.social @harvardmed.bsky.social
S. Urbut's talk @broadinstitute.org A Practical Primer on Bayesian Statistics youtube.com/watch?v=jcFS...
@mgbresearch.bsky.social @harvardmed.bsky.social
Reposted by Sanghyeon Park
Most disease-associated GWAS signals fall in the non-coding genome🧬
Although assumed to influence expression, pinpointing the causal gene isn't easy.
Two ways include:
1⃣eQTL mapping in relevant tissues/cells
2⃣in vitro CRISPRi screens
This preprint compares the two👇
Although assumed to influence expression, pinpointing the causal gene isn't easy.
Two ways include:
1⃣eQTL mapping in relevant tissues/cells
2⃣in vitro CRISPRi screens
This preprint compares the two👇
May 7, 2025 at 7:24 AM
Most disease-associated GWAS signals fall in the non-coding genome🧬
Although assumed to influence expression, pinpointing the causal gene isn't easy.
Two ways include:
1⃣eQTL mapping in relevant tissues/cells
2⃣in vitro CRISPRi screens
This preprint compares the two👇
Although assumed to influence expression, pinpointing the causal gene isn't easy.
Two ways include:
1⃣eQTL mapping in relevant tissues/cells
2⃣in vitro CRISPRi screens
This preprint compares the two👇
Reposted by Sanghyeon Park
Coronary artery calcium score improves atherosclerotic cardiovascular disease (ASCVD) risk assessment, particularly in individuals at borderline or intermediate ASCVD risk who are not already taking statin medication. https://ja.ma/4iw5HRE
Cardiac CT Calcium Score
This JAMA Insights explores how coronary artery calcium and computed tomography calcium scores can improve risk assessment for atherosclerotic cardiovascular disease and inform recommendations for statin therapy.
ja.ma
April 22, 2025 at 6:00 PM
Coronary artery calcium score improves atherosclerotic cardiovascular disease (ASCVD) risk assessment, particularly in individuals at borderline or intermediate ASCVD risk who are not already taking statin medication. https://ja.ma/4iw5HRE
Reposted by Sanghyeon Park
A study in Nature Medicine shows that a meta-prediction framework integrating polygenic risk scores spanning multiple conditions and nongenetic factors had superior performance in predicting the 10-year risk of coronary artery disease. go.nature.com/4igXqAJ 🔒
April 21, 2025 at 4:38 PM
A study in Nature Medicine shows that a meta-prediction framework integrating polygenic risk scores spanning multiple conditions and nongenetic factors had superior performance in predicting the 10-year risk of coronary artery disease. go.nature.com/4igXqAJ 🔒