@samtobam.bsky.social
Reposted
PAQman: reference-free ensemble evaluation of long-read eukaryotic genome assemblies https://www.biorxiv.org/content/10.1101/2025.09.11.675652v1
September 17, 2025 at 1:48 AM
PAQman: reference-free ensemble evaluation of long-read eukaryotic genome assemblies https://www.biorxiv.org/content/10.1101/2025.09.11.675652v1
Reposted
O'Donnell et al. investigated the evolution of Starships - a class of giant transposons - in Aspergillus and Penicillium, finding that domesticated lineages exhibited greater Starship content than relatives from non-human environments.
🔗 doi.org/10.1093/gbe/evaf125
#genome #evolution #TEsky
🔗 doi.org/10.1093/gbe/evaf125
#genome #evolution #TEsky
July 18, 2025 at 12:56 PM
O'Donnell et al. investigated the evolution of Starships - a class of giant transposons - in Aspergillus and Penicillium, finding that domesticated lineages exhibited greater Starship content than relatives from non-human environments.
🔗 doi.org/10.1093/gbe/evaf125
#genome #evolution #TEsky
🔗 doi.org/10.1093/gbe/evaf125
#genome #evolution #TEsky
Reposted
📢 New paper out in Mol Syst Biol!
During the development of WT yeast colonies, small cell subpopulations experience transient, high-intensity mutational bursts. Such hypermutation episodes are modulated by the DNA damage tolerance pathway 🧬
🔗 www.embopress.org/doi/full/10....
During the development of WT yeast colonies, small cell subpopulations experience transient, high-intensity mutational bursts. Such hypermutation episodes are modulated by the DNA damage tolerance pathway 🧬
🔗 www.embopress.org/doi/full/10....
June 9, 2025 at 1:02 PM
📢 New paper out in Mol Syst Biol!
During the development of WT yeast colonies, small cell subpopulations experience transient, high-intensity mutational bursts. Such hypermutation episodes are modulated by the DNA damage tolerance pathway 🧬
🔗 www.embopress.org/doi/full/10....
During the development of WT yeast colonies, small cell subpopulations experience transient, high-intensity mutational bursts. Such hypermutation episodes are modulated by the DNA damage tolerance pathway 🧬
🔗 www.embopress.org/doi/full/10....
Reposted
🚨 We're hiring! 🚨
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
Postdoc_Evol_Genomics_Sorbonne.docx
Postdoctoral position in Yeast Evolutionary Genomics Hosting unit Laboratory of Computational, Quantitative, and Synthetic Biology (CQSB). The CQSB is an interdisciplinary research unit within the ...
docs.google.com
May 19, 2025 at 3:41 PM
🚨 We're hiring! 🚨
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
Reposted
We show eukaryotic #HGT across >100 million years of evolution through simple co-culture: the fungal equivalent of taking yourself for a swim with a platypus and walking away with a new bill 🧪🍄🦆🚀 Great work everyone!
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
March 7, 2025 at 1:51 PM
We show eukaryotic #HGT across >100 million years of evolution through simple co-culture: the fungal equivalent of taking yourself for a swim with a platypus and walking away with a new bill 🧪🍄🦆🚀 Great work everyone!
Reposted
A natural mechanism of eukaryotic horizontal gene transfer https://www.biorxiv.org/content/10.1101/2025.02.28.640899v1
March 6, 2025 at 2:42 PM
A natural mechanism of eukaryotic horizontal gene transfer https://www.biorxiv.org/content/10.1101/2025.02.28.640899v1