Sam Fenske
@samfenske.bsky.social
PhD student @yalecbb.bsky.social in the lab of @hattaca.bsky.social | interested in single-cell genomics, drug discovery, and AI | former data analyst at Northwestern PCCM | alum of WashU BME
Reposted by Sam Fenske
Our lab at Yale @yalemedicine.bsky.social seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML! jobrxiv.org/job/yale-uni...
Postdoctoral Fellow, Hattie Chung Lab (Yale School of Medicine)
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
August 8, 2025 at 6:06 PM
Our lab at Yale @yalemedicine.bsky.social seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML! jobrxiv.org/job/yale-uni...
🚨 Our paper is out in Scientific Reports! Amazing collaboration with Alec Peltekian, @catgaohow.bsky.social, and Ankit Agrawal.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Developing and validating machine learning models to predict next-day extubation - Scientific Reports
Scientific Reports - Developing and validating machine learning models to predict next-day extubation
www.nature.com
July 30, 2025 at 7:16 PM
🚨 Our paper is out in Scientific Reports! Amazing collaboration with Alec Peltekian, @catgaohow.bsky.social, and Ankit Agrawal.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sam Fenske
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...
May 15, 2025 at 6:05 PM
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...
Reposted by Sam Fenske
What if LLMs could “read” & “write” biology? 🤔
Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝
🔗 Blog: research.google/blog/teachin...
🔗 Preprint: biorxiv.org/content/10.1...
Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝
🔗 Blog: research.google/blog/teachin...
🔗 Preprint: biorxiv.org/content/10.1...
Teaching machines the language of biology: Scaling large language models for next-generation single-cell analysis
research.google
April 18, 2025 at 2:14 PM
What if LLMs could “read” & “write” biology? 🤔
Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝
🔗 Blog: research.google/blog/teachin...
🔗 Preprint: biorxiv.org/content/10.1...
Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝
🔗 Blog: research.google/blog/teachin...
🔗 Preprint: biorxiv.org/content/10.1...
Reposted by Sam Fenske
Reposted by Sam Fenske
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Reposted by Sam Fenske
"Despite being preventable and highly curable, TB continues to have devastating health, social, and economic impacts globally." - Cenyun Guan, MPH '25 (@yaleemd.bsky.social)
#WorldTBDay2025
#WorldTBDay2025
Happy World TB Day! 🙌
Today, we have EMD MPH student Cenyun Guan at @yalesph.bsky.social to discuss the current tuberculosis (TB) situation and the urgent need to raise public awareness and further invest to end TB.
Read more here! ysph.yale.edu/news-article...
#PublicHealth
#WorldTBDay
Today, we have EMD MPH student Cenyun Guan at @yalesph.bsky.social to discuss the current tuberculosis (TB) situation and the urgent need to raise public awareness and further invest to end TB.
Read more here! ysph.yale.edu/news-article...
#PublicHealth
#WorldTBDay
March 24, 2025 at 7:16 PM
"Despite being preventable and highly curable, TB continues to have devastating health, social, and economic impacts globally." - Cenyun Guan, MPH '25 (@yaleemd.bsky.social)
#WorldTBDay2025
#WorldTBDay2025
Reposted by Sam Fenske
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.
jamanetwork.com
March 10, 2025 at 2:15 PM
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
Reposted by Sam Fenske
Anne Carpenter writes about the science cuts: “this is like suddenly announcing that you will pay for doctors and nurses but not the hospital building they work in” for the LaPorte Herald Dispatch in IN 🌽
🧪🧬🔬🏠
@drannecarpenter.bsky.social
www.lpheralddispatch.com/opinion/gues...
🧪🧬🔬🏠
@drannecarpenter.bsky.social
www.lpheralddispatch.com/opinion/gues...
Indiana’s health and economy depends on U.S.-funded science
When people ask me what city I’m from, I say I’m not from a city – I’m from a county!
www.lpheralddispatch.com
March 1, 2025 at 12:46 AM
Anne Carpenter writes about the science cuts: “this is like suddenly announcing that you will pay for doctors and nurses but not the hospital building they work in” for the LaPorte Herald Dispatch in IN 🌽
🧪🧬🔬🏠
@drannecarpenter.bsky.social
www.lpheralddispatch.com/opinion/gues...
🧪🧬🔬🏠
@drannecarpenter.bsky.social
www.lpheralddispatch.com/opinion/gues...
Reposted by Sam Fenske
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling
Building predictive models of the cell requires systematically mapping how perturbations reshape each cell's state, function, and behavior. Here, we present Tahoe-100M, a giga-scale single-cell atlas ...
www.biorxiv.org
February 25, 2025 at 1:25 PM
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Reposted by Sam Fenske
A very innovative approach to cancer: engineering fat cells to convert to beige fat to starve tumors, outcompeting 5 types of cancer in experimental models
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
Implantation of engineered adipocytes suppresses tumor progression in cancer models - Nature Biotechnology
Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.
www.nature.com
February 4, 2025 at 2:56 PM
A very innovative approach to cancer: engineering fat cells to convert to beige fat to starve tumors, outcompeting 5 types of cancer in experimental models
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
Reposted by Sam Fenske
Post the amazing science things you have done with federal funding.
January 28, 2025 at 8:51 PM
Post the amazing science things you have done with federal funding.