Stuart O'Connor
@sajoconnor.bsky.social
Doctor, Anaesthetist, Neuroscientist, Researcher
Reposted by Stuart O'Connor
Chronic stress, impaired autophagy, and depression (as opposed to acute stress)
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Chronic stress drives depression by disrupting cellular housekeeping
Boosting the recycling process known as autophagy — impaired in the brain during prolonged stress — has the potential to restore normal neuronal activity and treat depression.
www.nature.com
April 10, 2025 at 2:34 PM
Chronic stress, impaired autophagy, and depression (as opposed to acute stress)
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Stuart O'Connor
Imamura and Kelz discuss the neuropharmacology of orexin/hypocretin signaling and its potential to meaningfully impact clinical care. Read the new editorial: ow.ly/f85p50VfCXT
March 13, 2025 at 7:55 PM
Imamura and Kelz discuss the neuropharmacology of orexin/hypocretin signaling and its potential to meaningfully impact clinical care. Read the new editorial: ow.ly/f85p50VfCXT
Reposted by Stuart O'Connor
An Australian man in his forties has become the first person in the world to leave hospital with an artificial heart made of titanium
The device could be a temporary measure for those waiting for a donor organ
https://go.nature.com/3FCPcFn
The device could be a temporary measure for those waiting for a donor organ
https://go.nature.com/3FCPcFn
Man survives with titanium heart for 100 days – a world first
The device, to be tested in more people, could be used as a temporary measure for those waiting for a donor organ.
go.nature.com
March 13, 2025 at 1:08 PM
An Australian man in his forties has become the first person in the world to leave hospital with an artificial heart made of titanium
The device could be a temporary measure for those waiting for a donor organ
https://go.nature.com/3FCPcFn
The device could be a temporary measure for those waiting for a donor organ
https://go.nature.com/3FCPcFn
My latest #BJAEd podcast discussing Jet Ventilation with Dr Craig Lyons is available now:
Jet Ventilation
open.spotify.com
March 12, 2025 at 4:04 PM
My latest #BJAEd podcast discussing Jet Ventilation with Dr Craig Lyons is available now:
Reposted by Stuart O'Connor
The presence of a pattern called a sleep spindle helps to predict which people will recover from an unresponsive state
https://go.nature.com/3Dt9WPn
https://go.nature.com/3Dt9WPn
Who’s likely to wake up from a coma? Brain waves provide a clue
The presence of a pattern called a sleep spindle helps to predict which people will recover from an unresponsive state.
go.nature.com
March 10, 2025 at 3:20 PM
The presence of a pattern called a sleep spindle helps to predict which people will recover from an unresponsive state
https://go.nature.com/3Dt9WPn
https://go.nature.com/3Dt9WPn
Reposted by Stuart O'Connor
Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age
https://go.nature.com/4kjeHf2
https://go.nature.com/4kjeHf2
‘Slime’ keeps the brain safe ― and could guard against ageing
Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age, studies in mice show.
go.nature.com
February 27, 2025 at 10:32 AM
Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age
https://go.nature.com/4kjeHf2
https://go.nature.com/4kjeHf2
Reposted by Stuart O'Connor
A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.
https://go.nature.com/41a7Zzj
https://go.nature.com/41a7Zzj
Rare genetic disorder treated in womb for the first time
The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.
go.nature.com
February 20, 2025 at 11:17 AM
A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.
https://go.nature.com/41a7Zzj
https://go.nature.com/41a7Zzj