Sajjita Saha
@sajjitasaha.bsky.social
Graduate Student @Sophie Martin Lab 🧬🔬🧫@UniversityofGeneva | Hobby Pianist🎹 | Art enthusiast 🎨|
Reposted by Sajjita Saha
Super excited that this story by @borissieber.bsky.social is now on BioRxiv!
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
September 25, 2025 at 7:48 PM
Super excited that this story by @borissieber.bsky.social is now on BioRxiv!
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !
See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
Reposted by Sajjita Saha
The lab is on a roll. 2nd preprint in as many weeks!
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse
Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...
www.biorxiv.org
May 6, 2025 at 11:20 AM
The lab is on a roll. 2nd preprint in as many weeks!
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
Reposted by Sajjita Saha
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
May 2, 2025 at 8:55 AM
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction.
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...
A very cool work led by @valthomas.bsky.social and nice collaboration with Andrea Picco and @kaksonen.bsky.social!
www.biorxiv.org/content/10.1...