Sahana Holla
@sahanaholla.bsky.social
Asst. Prof. @tifrhyderabad.bsky.social | Interested in all things Epigenetics and the 3D Genome | Postdoc @NCIResearchCtr | PhD @iiscbangalore
https://scholar.google.com/citations?user=NW0XGJgAAAAJ&hl=en
https://scholar.google.com/citations?user=NW0XGJgAAAAJ&hl=en
Pinned
Sahana Holla
@sahanaholla.bsky.social
· Jun 29
Thrilled to share that I’ve joined @tifrhyderabad.bsky.social as an Assistant Professor! Grateful to my mentors (esp @grewalsh.bsky.social and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!
Grateful for the warm welcome @tifrhyderabad.bsky.social :) Thrilled to be part of this vibrant scientific community and eager to build an exciting research program!
We are delighted to welcome our newest faculty member, Sahana Holla (@sahanaholla.bsky.social). She is investigating the biological significance of 3D genome organization during development & disease, with an interdisciplinary approach combining genomics, proteomics, and advanced imaging.
July 1, 2025 at 5:35 PM
Grateful for the warm welcome @tifrhyderabad.bsky.social :) Thrilled to be part of this vibrant scientific community and eager to build an exciting research program!
Reposted by Sahana Holla
So proud of you, @sahanaholla! Watching your journey has been such a joy. Wishing you all the best as you begin this exciting new chapter at TIFRH. They’re lucky to have you!
Thrilled to share that I’ve joined @tifrhyderabad.bsky.social as an Assistant Professor! Grateful to my mentors (esp @grewalsh.bsky.social and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!
June 29, 2025 at 12:08 PM
So proud of you, @sahanaholla! Watching your journey has been such a joy. Wishing you all the best as you begin this exciting new chapter at TIFRH. They’re lucky to have you!
Thrilled to share that I’ve joined @tifrhyderabad.bsky.social as an Assistant Professor! Grateful to my mentors (esp @grewalsh.bsky.social and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!
June 29, 2025 at 10:50 AM
Thrilled to share that I’ve joined @tifrhyderabad.bsky.social as an Assistant Professor! Grateful to my mentors (esp @grewalsh.bsky.social and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!
Reposted by Sahana Holla
What was that you said? You are looking for new #RNA research to read in the weekend?
You are in luck!
📣 📣 Check out the new preprint from our lab!!!! 📣 📣
www.biorxiv.org/content/10.1...
You are in luck!
📣 📣 Check out the new preprint from our lab!!!! 📣 📣
www.biorxiv.org/content/10.1...
AGO2 slicing of a domesticated retrotransposon is necessary for normal vasculature development
Argonaute (AGO) mediated slicing of RNA, also known as RNAi, is a highly conserved phenomenon that is evolutionarily linked to the repression of transposons and other repeats. Although RNAi is no long...
www.biorxiv.org
April 4, 2025 at 5:35 PM
What was that you said? You are looking for new #RNA research to read in the weekend?
You are in luck!
📣 📣 Check out the new preprint from our lab!!!! 📣 📣
www.biorxiv.org/content/10.1...
You are in luck!
📣 📣 Check out the new preprint from our lab!!!! 📣 📣
www.biorxiv.org/content/10.1...
Reposted by Sahana Holla
🎉 CONGRATULATIONS to Manjit Srivastav, Diego Folco, Patroula Nathanailidou, Anupa Anil, Drisya Vijaykumari, Shweta Jain, Jothy Dhakshnamoorthy, David Wheeler, and our amazing collaborators Maura O’Neill and Thorkell Andresson! Your unwavering dedication, hard work, and passion are truly inspiring 🙌✨
January 3, 2025 at 3:52 PM
🎉 CONGRATULATIONS to Manjit Srivastav, Diego Folco, Patroula Nathanailidou, Anupa Anil, Drisya Vijaykumari, Shweta Jain, Jothy Dhakshnamoorthy, David Wheeler, and our amazing collaborators Maura O’Neill and Thorkell Andresson! Your unwavering dedication, hard work, and passion are truly inspiring 🙌✨
Reposted by Sahana Holla
🔬Decoding Silencing: How Heterochromatin Transcribes to Silence Itself!
🧬 Discover how a pioneer transcription factor-like complex infiltrates repressive heterochromatin, producing transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation www.nature.com/articles/s41...
🧬 Discover how a pioneer transcription factor-like complex infiltrates repressive heterochromatin, producing transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation www.nature.com/articles/s41...
January 3, 2025 at 3:46 PM
🔬Decoding Silencing: How Heterochromatin Transcribes to Silence Itself!
🧬 Discover how a pioneer transcription factor-like complex infiltrates repressive heterochromatin, producing transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation www.nature.com/articles/s41...
🧬 Discover how a pioneer transcription factor-like complex infiltrates repressive heterochromatin, producing transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation www.nature.com/articles/s41...
Reposted by Sahana Holla
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Evolution and function of chromatin domains across the tree of life - Nature Structural & Molecular Biology
Szalay et al. discuss cross-kingdom similarities and differences in 3D chromatin folding in relation to gene regulation, including in bacteria, archaea, mammals and plants. This comparison reveals cer...
www.nature.com
November 28, 2024 at 12:48 PM
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Reposted by Sahana Holla
Very happy to see @grothlab.bsky.social , @helink.bsky.social and @grewalsh.bsky.social all migrating over here! All pillars of the the #epigenetics and chromatin community.
November 26, 2024 at 9:44 AM
Very happy to see @grothlab.bsky.social , @helink.bsky.social and @grewalsh.bsky.social all migrating over here! All pillars of the the #epigenetics and chromatin community.