Krishanu Saha
@sahakris.bsky.social
Professor at Univ. of Wisconsin-Madison (@WIDiscovery @HoltzCenter @Forward_BIO @UWMadGIE) + Genome Editor (@somaticediting) + Cell Bioengineer (@CMaT_ERC)
@laurensarko.bsky.social gave a great talk at #ASGCT2025:
CRISPR-engineered CAR T cells targeting senescence-associated uPAR
Clear, compelling science—and a great discussion that followed. Exciting to see where this work is headed.
#CRISPR #CellTherapy
@warfnews.bsky.social
CRISPR-engineered CAR T cells targeting senescence-associated uPAR
Clear, compelling science—and a great discussion that followed. Exciting to see where this work is headed.
#CRISPR #CellTherapy
@warfnews.bsky.social
May 16, 2025 at 5:32 PM
@laurensarko.bsky.social gave a great talk at #ASGCT2025:
CRISPR-engineered CAR T cells targeting senescence-associated uPAR
Clear, compelling science—and a great discussion that followed. Exciting to see where this work is headed.
#CRISPR #CellTherapy
@warfnews.bsky.social
CRISPR-engineered CAR T cells targeting senescence-associated uPAR
Clear, compelling science—and a great discussion that followed. Exciting to see where this work is headed.
#CRISPR #CellTherapy
@warfnews.bsky.social
Looking forward to this timely Scientific Symposium and conversation on #CRISPR #GeneEditing at #ASGCT2025!
“Who’s Afraid of Off-Target Editing?”
1:30–3:15 PM CT (Room 293–296)
With Claire Clelland (UCSF) & Kiran Musunuru (Penn) of
@somaticediting Join us! #GenomicMedicine
“Who’s Afraid of Off-Target Editing?”
1:30–3:15 PM CT (Room 293–296)
With Claire Clelland (UCSF) & Kiran Musunuru (Penn) of
@somaticediting Join us! #GenomicMedicine
May 13, 2025 at 1:20 PM
Looking forward to this timely Scientific Symposium and conversation on #CRISPR #GeneEditing at #ASGCT2025!
“Who’s Afraid of Off-Target Editing?”
1:30–3:15 PM CT (Room 293–296)
With Claire Clelland (UCSF) & Kiran Musunuru (Penn) of
@somaticediting Join us! #GenomicMedicine
“Who’s Afraid of Off-Target Editing?”
1:30–3:15 PM CT (Room 293–296)
With Claire Clelland (UCSF) & Kiran Musunuru (Penn) of
@somaticediting Join us! #GenomicMedicine
🎉 Huge congrats to our newest PhD, Dr. Khajanchi (@omgitsnamita), on her stellar defense! 🌟 She delivered an outstanding presentation on her groundbreaking work developing a tunable #CRISPR genome editing system in human cells. Stay tuned for the preprint! 📄👏
November 14, 2024 at 4:46 AM
🎉 Huge congrats to our newest PhD, Dr. Khajanchi (@omgitsnamita), on her stellar defense! 🌟 She delivered an outstanding presentation on her groundbreaking work developing a tunable #CRISPR genome editing system in human cells. Stay tuned for the preprint! 📄👏
Please join me in congratulating @Shankar_K2, Ph.D. on her thesis defense! 🎓 By integrating #CRISPR genome editing w/ cell engineering, Dr. Shankar has crafted programmable cell therapies that are foundational to our lab’s new directions. @CMaT_ERC @UWCarbone @UWMadison_BME
November 14, 2024 at 4:46 AM
Please join me in congratulating @Shankar_K2, Ph.D. on her thesis defense! 🎓 By integrating #CRISPR genome editing w/ cell engineering, Dr. Shankar has crafted programmable cell therapies that are foundational to our lab’s new directions. @CMaT_ERC @UWCarbone @UWMadison_BME
At #ASGCT2024, we're showcasing advances in non-viral gene editing, CAR T cell therapies, & high-throughput screening. Explore our work on vision restoration, cancer therapy, and ethical challenges in the field. Join us to learn about the latest progress in #GeneTherapy research
November 14, 2024 at 4:46 AM
At #ASGCT2024, we're showcasing advances in non-viral gene editing, CAR T cell therapies, & high-throughput screening. Explore our work on vision restoration, cancer therapy, and ethical challenges in the field. Join us to learn about the latest progress in #GeneTherapy research
Join us this Thursday, Mar 21!
A Question of Beginnings: Lab Embryos Between Nature and Synthesis
with @jacob_hanna, @cartersnead, @ArnoldEisen, @SJasanoff, @JudyNorsigian, @jdhardin1959 + many more.
@GenomeObserv
Registration:
A Question of Beginnings: Lab Embryos Between Nature and Synthesis
with @jacob_hanna, @cartersnead, @ArnoldEisen, @SJasanoff, @JudyNorsigian, @jdhardin1959 + many more.
@GenomeObserv
Registration:
November 14, 2024 at 4:46 AM
Join us this Thursday, Mar 21!
A Question of Beginnings: Lab Embryos Between Nature and Synthesis
with @jacob_hanna, @cartersnead, @ArnoldEisen, @SJasanoff, @JudyNorsigian, @jdhardin1959 + many more.
@GenomeObserv
Registration:
A Question of Beginnings: Lab Embryos Between Nature and Synthesis
with @jacob_hanna, @cartersnead, @ArnoldEisen, @SJasanoff, @JudyNorsigian, @jdhardin1959 + many more.
@GenomeObserv
Registration:
Finding resonance with many others thinking about global governance of emerging tech here at the #ParisPeaceForum2023. Come see our roundtable discussion on #CRISPR genome editing tomorrow.
November 14, 2024 at 4:45 AM
Finding resonance with many others thinking about global governance of emerging tech here at the #ParisPeaceForum2023. Come see our roundtable discussion on #CRISPR genome editing tomorrow.
Happy to participate as an expert for this excellent @USGAO report on the applications, challenges, and policy options for regenerative medicine. Lots of exciting work ahead... #CellTherapy #GeneTherapy #CRISPR @NASEM_Health @CMaT_ERC @somaticediting
November 14, 2024 at 4:45 AM
Happy to participate as an expert for this excellent @USGAO report on the applications, challenges, and policy options for regenerative medicine. Lots of exciting work ahead... #CellTherapy #GeneTherapy #CRISPR @NASEM_Health @CMaT_ERC @somaticediting
We are lucky to have @danielevanbauer visit us on Monday! Join us at noon for his seminar on #CRISPR gene editing of blood stem cells. @UW_CHGPM @uwsmph @UWMadEngr @UWCarbone @UWMadScience @UWSCRMC @UWMadison_CGSI @WIDiscovery
November 14, 2024 at 4:45 AM
We are lucky to have @danielevanbauer visit us on Monday! Join us at noon for his seminar on #CRISPR gene editing of blood stem cells. @UW_CHGPM @uwsmph @UWMadEngr @UWCarbone @UWMadScience @UWSCRMC @UWMadison_CGSI @WIDiscovery
The @somaticediting program and toolkit highlighted internationally here at #HGESummit by @ncats_nih_gov Director, Dr. Joni Rutter. Check out the data in the toolkit here:
November 14, 2024 at 4:45 AM
The @somaticediting program and toolkit highlighted internationally here at #HGESummit by @ncats_nih_gov Director, Dr. Joni Rutter. Check out the data in the toolkit here:
Hiring! Looking for scientists and project managers - from academia and/or industry - who want to develop the next generation of #CRISPR cell/gene therapies. We have active grants aiming to move new nonviral drug candidates into first-in-human clinical trials. Please circulate.
November 14, 2024 at 4:45 AM
Hiring! Looking for scientists and project managers - from academia and/or industry - who want to develop the next generation of #CRISPR cell/gene therapies. We have active grants aiming to move new nonviral drug candidates into first-in-human clinical trials. Please circulate.
Can the differences in our genes affect CRISPR drugs? Yes, and I discuss beautiful work on human genetic diversity in @NatureGenet by Cancellieri, @lucapinello, Dan Bauer, @shengdarqtsai+colleagues @somaticediting
November 14, 2024 at 4:44 AM
Can the differences in our genes affect CRISPR drugs? Yes, and I discuss beautiful work on human genetic diversity in @NatureGenet by Cancellieri, @lucapinello, Dan Bauer, @shengdarqtsai+colleagues @somaticediting
We're delighted to welcome @shengdarqtsai to campus this week. Please come check out his @UWMadison_CGSI seminar in person or virtually:
Thursday 9/8 1:30 pm CDT
CRISPR Genome Editing Technologies for Therapeutics
@UWMadison @uwsmph @UW_CHGPM @somaticediting
DM me for the link
Thursday 9/8 1:30 pm CDT
CRISPR Genome Editing Technologies for Therapeutics
@UWMadison @uwsmph @UW_CHGPM @somaticediting
DM me for the link
November 14, 2024 at 4:44 AM
We're delighted to welcome @shengdarqtsai to campus this week. Please come check out his @UWMadison_CGSI seminar in person or virtually:
Thursday 9/8 1:30 pm CDT
CRISPR Genome Editing Technologies for Therapeutics
@UWMadison @uwsmph @UW_CHGPM @somaticediting
DM me for the link
Thursday 9/8 1:30 pm CDT
CRISPR Genome Editing Technologies for Therapeutics
@UWMadison @uwsmph @UW_CHGPM @somaticediting
DM me for the link
Hear about our latest progress with T cells in @kpmueller1's @CMB_UWMadison defense on Monday. DM me for the Zoom link.
November 14, 2024 at 4:44 AM
Hear about our latest progress with T cells in @kpmueller1's @CMB_UWMadison defense on Monday. DM me for the Zoom link.
Join us to think through new directions for synthetic biology to improve heart, lung, blood, and sleep (HLBS) health. @nih_nhlbi Virtual Workshop in May with a fantastic group of speakers. Register for free here: draft agenda below
November 14, 2024 at 4:44 AM
Join us to think through new directions for synthetic biology to improve heart, lung, blood, and sleep (HLBS) health. @nih_nhlbi Virtual Workshop in May with a fantastic group of speakers. Register for free here: draft agenda below
Finished an energizing @CMaT_ERC retreat today! A special day for the lab as @smerchette (with @melissa_kinney) @Shankar_K2 @kpmueller1 and Dan all receiving recognition today. Congratulations to all of these fantastic students! @WIDiscovery @UWMadison_BME @CMB_UWMadison
November 14, 2024 at 4:44 AM
Finished an energizing @CMaT_ERC retreat today! A special day for the lab as @smerchette (with @melissa_kinney) @Shankar_K2 @kpmueller1 and Dan all receiving recognition today. Congratulations to all of these fantastic students! @WIDiscovery @UWMadison_BME @CMB_UWMadison
Looking to control #CRISPR genome editing for therapeutic purposes? Check out our new @MolTherapy Review written by @omgitsnamita and me. Thank you to @somaticediting @CMaT_ERC, in particular @Roy_Lab_Thinks, for very helpful discussions.
November 14, 2024 at 4:44 AM
Looking to control #CRISPR genome editing for therapeutic purposes? Check out our new @MolTherapy Review written by @omgitsnamita and me. Thank you to @somaticediting @CMaT_ERC, in particular @Roy_Lab_Thinks, for very helpful discussions.
Congratulations🍾 for a successful doctoral defense, Dr. Kaivalya Molugu @KaivalyaMolugu! #WomenInScience a huge thanks to the committee, her local and global (🇮🇳) support network, and @WIDiscovery @UWSCRMC @CMaT_ERC @NIGMS
November 14, 2024 at 4:44 AM
Congratulations🍾 for a successful doctoral defense, Dr. Kaivalya Molugu @KaivalyaMolugu! #WomenInScience a huge thanks to the committee, her local and global (🇮🇳) support network, and @WIDiscovery @UWSCRMC @CMaT_ERC @NIGMS
Go Bucks! @CMaT_ERC
November 14, 2024 at 4:43 AM
Go Bucks! @CMaT_ERC
For #CRISPR folks: here's a new nonviral delivery vector developed @WIDiscovery @UWMadison in collaboration with Sarah Gong and Bikash Pattnaik. A super talented postdoc @Amr_Abdeen moved this forward in my lab
November 14, 2024 at 4:43 AM
For #CRISPR folks: here's a new nonviral delivery vector developed @WIDiscovery @UWMadison in collaboration with Sarah Gong and Bikash Pattnaik. A super talented postdoc @Amr_Abdeen moved this forward in my lab
Congratulations to @A_Movaghar on defending her PhD thesis today! Over 5 years, she brought together @WIDiscovery @UWWaismanCenter @mfldclinic in truly new ways. Watching students succeed and defend fearless science is likely the best part of my job...what a treat.
November 14, 2024 at 4:42 AM
Congratulations to @A_Movaghar on defending her PhD thesis today! Over 5 years, she brought together @WIDiscovery @UWWaismanCenter @mfldclinic in truly new ways. Watching students succeed and defend fearless science is likely the best part of my job...what a treat.
After more than a decade, what a beautiful day to return to campus. I have been looking forward to today for a long time...giving a bioengineering seminar at noon and reconnecting with transformative professors like @kehealy, David Schaffer and many others!
November 14, 2024 at 4:42 AM
After more than a decade, what a beautiful day to return to campus. I have been looking forward to today for a long time...giving a bioengineering seminar at noon and reconnecting with transformative professors like @kehealy, David Schaffer and many others!
Our new paper is out! We developed a platform to see reprogrammed, pluripotent #stemcells based on just looking at the cell nuclei. Why? Because we can identify iPSCs without destroying them; useful for disease modeling, cell therapy & regen med 1/n
November 14, 2024 at 4:42 AM
Our new paper is out! We developed a platform to see reprogrammed, pluripotent #stemcells based on just looking at the cell nuclei. Why? Because we can identify iPSCs without destroying them; useful for disease modeling, cell therapy & regen med 1/n
So we coated #CRISPR genome editors with an ultra-thin plastic coating...WHY? Because we can freeze dry it into a nanoparticle powder and inject it into the body to edit genes in different tissues - like the eye or the muscle. @NatureNano (1/n)
November 14, 2024 at 4:42 AM
So we coated #CRISPR genome editors with an ultra-thin plastic coating...WHY? Because we can freeze dry it into a nanoparticle powder and inject it into the body to edit genes in different tissues - like the eye or the muscle. @NatureNano (1/n)
Yesterday at our group meeting, my very generous lab surprised me with custom shirts and a cake to celebrate my tenure decision. I’m very happy 😀 to be surrounded by a incredibly thoughtful and positive group — one that takes time to enjoy the success by others in the group.
November 14, 2024 at 4:42 AM
Yesterday at our group meeting, my very generous lab surprised me with custom shirts and a cake to celebrate my tenure decision. I’m very happy 😀 to be surrounded by a incredibly thoughtful and positive group — one that takes time to enjoy the success by others in the group.