Jeff Sperry
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safechem79.bsky.social
Jeff Sperry
@safechem79.bsky.social
Director, Process Chemistry at Vertex Pharma (Boston) | Process Safety | High-Throughput Experimentation (HTE) | Oligonucleotides | views my own
Any experienced peptide chemists out there looking for a new challenge? I have an opening on my team

vrtx.wd5.myworkdayjobs.com/en-US/vertex...
Process Chemistry Senior Principal Scientist, Synthetic Peptide Chemist
Job Description General Summary: Vertex is seeking an experienced peptide chemist to join the Process Chemistry group. In this lab-based position you will be responsible for the synthesis, purificatio...
vrtx.wd5.myworkdayjobs.com
February 27, 2025 at 11:10 PM
Huge loss for the chemistry community. Absolutely loved my time at UPenn. I wouldn’t be where I am today if it wasn’t for Amos’ mentorship and the friends I made in the group
We are deeply saddened to share that our friend and colleague Professor Amos B. Smith III has passed away. Amos joined Penn in 1973 and was a mainstay in our organic chemistry division. He recently celebrated 50 years of service to @upenn.edu @pennsas.bsky.social.
February 3, 2025 at 9:02 PM
Reposted by Jeff Sperry
If you care about visualization of scientific data and creating clear, impactful scientific publications, I highly recommend this podcast featuring my esteemed colleague Bang Wong. He also has a fantastic set of papers on this topic #DataVisualization www.buzzsprout.com/558574/episo...
S5E6: Writing Impactful Publications - NINDS's Building Up the Nerve
In the fifth Season of the National Institute of Neurological Disorders and Stroke’s Building Up the Nerve podcast, we help you strengthen your science communication skills with tools and advice to us...
www.buzzsprout.com
December 27, 2024 at 12:13 AM
Probably my most controversial fb post (back when I actually used fb)
December 13, 2024 at 11:32 PM
Me trying In and Out for the first time
a man in a blue shirt is talking to a woman in a brooklyn nine-nine episode .
ALT: a man in a blue shirt is talking to a woman in a brooklyn nine-nine episode .
media.tenor.com
December 4, 2024 at 11:11 PM
My favorite line when recruiting for process chem:
November 28, 2024 at 3:52 PM
Reposted by Jeff Sperry
The long and ugly story of Cassava Sciences’ supposed Alzheimer’s drug simufilam is finally over. It should have ended well before this.
The Cassava Saga Finally Ends
www.science.org
November 26, 2024 at 5:42 PM
Reposted by Jeff Sperry
Skeetorial time! Let’s talk early human dose prediction. Not the fancy, need-tons-of-software and a DMPK pro kind. Just the kind that uses some basic algebra. HDP is a unifying concept for med chemists. It’s the master optimization parameter, and it can’t be easily cheated. 1/
a pink background with pills and capsules on it
ALT: a pink background with pills and capsules on it
media.tenor.com
November 23, 2024 at 8:43 PM
November 22, 2024 at 5:33 PM
Reposted by Jeff Sperry
Created a Starter Pack for Industry Chemists- let me know if you want in! #ChemSky
November 15, 2024 at 1:28 AM
Reposted by Jeff Sperry
Hard agree with all of this. Basic setting up of profile with pic and bio increases confidence in identity. Not that accounts can’t be spoofed, but it’s a start. My follows are flooded these last few days and I know I’m doing a lousy job of follow-backs. Help me know you’re you!
Hey, new users! Remember how suspicious Twitter egg profiles were?

No one trusts a blank profile.

Set an avatar, set a background, write your bio, and maybe post a couple of times before you start mass-following people, okay?
November 13, 2024 at 10:45 PM
Reposted by Jeff Sperry
PSA for #ChemSky
November 10, 2024 at 1:08 AM
Love seeing my followers drop on X
November 8, 2024 at 3:33 PM
Anybody going to CO for fall ACS?
December 19, 2023 at 9:24 PM
Reposted by Jeff Sperry
Getting into festive spirit with some chem Christmas carols.

#chemsky #nmr #chemistry #science #christmas
December 7, 2023 at 2:35 PM
THE REACTION IS SAFE IF RUN IN A SEALED VIAL!
ALL OF MY SUZUKI-MIYAURA REACTIONS ARE ORGANOCATALYZED!
December 4, 2023 at 9:15 AM
I started two manuscripts this week and I feel very academic
October 25, 2023 at 9:05 PM
Reskeet with how people would know if you suddenly became rich
October 21, 2023 at 2:52 PM
Reposted by Jeff Sperry
Next for #NationalChemistryWeek ⚛️ (theme “The Healing Power of Chemistry”), here are some things I think are true that I’ve distilled about drug discovery over time.

This series was originally posted on the other app and was livelier with GIFs, but I’ll record them here anyway.
October 20, 2023 at 11:03 AM
5+ hr flight and no one sitting beside me
September 25, 2023 at 11:54 AM
This is the first time I’ve been asked to review a paper where the chemistry actually blows my mind. Very cool stuff
September 20, 2023 at 2:31 PM
Using an image, show a movie you are sure you have watched more than 10 times
September 10, 2023 at 10:32 AM
Chemists working with stannanes in the 1960s
August 19, 2023 at 6:50 PM
Maybe a little late to this party but thanks for the invite @chemjobber.bsky.social 👊🏻
August 18, 2023 at 8:32 PM