RSC Chemical Biology
LightNews LightNews
banner
rscchembio.rsc.org
RSC Chemical Biology
@rscchembio.rsc.org
410 followers 49 following 61 posts
A gold open-access journal focused on innovative chemical biology tools and their application in exploring and manipulating molecular biological processes.

🌐 Website: rsc.li/rscchembio Published by @rsc.org
Posts Replies Media Videos
rscchembio.rsc.org
New in RSC Chemical Biology:
Convergent construction of N-terminally modified CCL5 chemokines for photoaffinity receptor pull-down using cross-aldol bioconjugations by Martin Fascione et al., from @york.ac.uk

Read the full paper here👉 doi.org/10.1039/D5CB...
November 5, 2025 at 8:04 AM
rscchembio.rsc.org
New research by Weijun Shen, Muyu Xu et al. at Shenzhen Bay Laboratory:

"Cell-based high-throughput screening using a target–NanoLuc fusion construct to identify molecular glue degraders of c-Myc oncoprotein"

Read the full paper here👉 doi.org/10.1039/D5CB...
October 29, 2025 at 12:32 PM
rscchembio.rsc.org
New from @llparker100.bsky.social et al. from @uminnpress.bsky.social

Novel terbium-sensitizing peptide substrates for cyclin-dependent kinase 5 (CDK5) and their demonstration in luminescence kinase assays

Read the full paper👉 doi.org/10.1039/D5CB...
October 21, 2025 at 2:30 PM
rscchembio.rsc.org
Fresh from RSC Chemical Biology: Hao et al. from the Chinese Academy of Sciences:

Structural basis of SIRT2 pre-catalysis NAD+ binding dynamics and mechanism

Read more 👉 doi.org/10.1039/D5CB...
October 15, 2025 at 1:48 PM
rscchembio.rsc.org
New from Christopher Coxon et al., from @edinburgh-uni.bsky.social

"19F NMR-tags for peptidyl prolyl conformation analysis"

Fluorinated tags + 19F NMR = fresh insights into proline cis/trans isomerism, a key player in protein folding + interactions.

Read the paper 👉 doi.org/10.1039/D5CB...
October 7, 2025 at 1:21 PM
rscchembio.rsc.org
Excited to support #ChemBioParis2025 this October 6 in Paris!
Our Executive Editor, Anna Rulka + Associate Editors Claudia Höbartner and Zaneta Nikolovska-Coleska are attending—come say hi!

Let’s connect and talk science and publishing!

🔗 chembioparis2025.com

#ChemicalBiology #ICBS #ECBS
October 2, 2025 at 3:06 PM
rscchembio.rsc.org
🧬 New study reveals how biosensors + crystallography can detect ligand-induced shape changes in ACh binding proteins—models for ion channels. A powerful toolkit for studying weak or fast interactions!
Read here: doi.org/10.1039/D5CB...
#RSCChemicalBiology #StructuralBiology #Biosensors
October 1, 2025 at 2:36 PM
rscchembio.rsc.org
🦠 Can resistant bacteria protect their neighbours? A new paper reveals how β-lactamase activity, membrane permeability & antibiotic type shape antibiotic sheltering in microbial communities.
Read it here: doi.org/10.1039/D5CB...
#RSCChemicalBiology #AntibioticResistance #BetaLactamase
September 23, 2025 at 12:49 PM
rscchembio.rsc.org
Congratulations to Johannes Broichhagen (@broichhagenj.bsky.social) & team—winners of RSC Chemical Biology’s Outstanding Early Career Researcher Award for cleavable dyes to track GPCR trafficking & signalling!
📖 Read the paper here: doi.org/10.1039/D4CB...
September 18, 2025 at 11:00 AM
rscchembio.rsc.org
🧬 Boosting mRNA stability through smart poly(A) tail design! New study explores chemical modifications that protect against degradation while preserving translation.
Read here: doi.org/10.1039/D5CB...
#RSCChemicalBiology #mRNA #RNAStability
September 17, 2025 at 11:16 AM
rscchembio.rsc.org
RSC Chem. Biol. & Molecular Omics are sponsoring the EMBL’s The Epitranscriptome (28–30 Oct)!

🗓️ Today (16 Sept) is the last day to register for on-site attendance – be part of it in person!
(Virtual registration open until 13 Oct.)
👉 www.embl.org/about/i...
#Epitranscriptome
September 16, 2025 at 10:47 AM
rscchembio.rsc.org
🧪 New in #RSCChemicalBiology: Breakthrough in phage display! By combining unnatural amino acids with CuAAC click chemistry, this study expands molecular diversity for next-gen ligand discovery.
doi.org/10.1039/D5CB...
#PhageDisplay #ChemicalBiology #ClickChemistry
September 9, 2025 at 12:41 PM
rscchembio.rsc.org
🚨 New paper on enhancing NIR-PIT for cancer treatment! SiPc-1, a silicon phthalocyanine analogue, targets HTLV-1-infected cells with selective toxicity. Find out how this breakthrough could shape the future of ATL treatment 👉doi.org/10.1039/D5CB...

#RSCChemicalBiology #NIRPIT #CancerResearch
September 3, 2025 at 3:05 PM
rscchembio.rsc.org
🧬 Explore our new collection Biomolecular Technologies! Guest edited by Sheel Dodani & Ariel Furst, it showcases advances in engineered small molecules, nucleic acids & proteins for biocatalysis, biosensing & synthetic biology.

🔗 Read now: https://rsc.li/cbbmt25
August 26, 2025 at 12:00 PM
rscchembio.rsc.org
Don’t forget! The Tri-Institutional Chem Bio Symposium is Aug 28 🧬
Proudly sponsored by RSC ChemBio + ‪@rscmedchem.rsc.org‬!
🗓️ Reg closes Aug 20
🧪 Posters welcome from all attendees
📍 At ‪@mskcancercenter.bsky.social‬

Be there!
#ChemBio #MedChem #ScienceSymposium #RSCJournals
August 11, 2025 at 2:57 PM
rscchembio.rsc.org
New in RSC Chemical Biology: EBI ⚡ — promising for food safety, but how can AI 🤖, MAP, and natural antimicrobials 🌱 help scale it up? We explore solutions in our latest review.
🔗 Read full article: doi.org/10.1039/D5CB...
#FoodSafety #EmergingTech #RSCChemicalBiology

July 21, 2025 at 6:47 PM
rscchembio.rsc.org
Excited to sponsor the 21st Tri-Institutional Chemical Biology Symposium on Aug 28 at ‪@mskcancercenter.bsky.social‬ 🎉
RSC Chemical Biology + ‪@rscmedchem.rsc.org‬ are proud to support this event 👩‍🔬👨‍🔬
Poster subs open! Reg by Aug 20 🔬🧪
#ChemBio #MedChem #TPCB #RSCJournals
July 21, 2025 at 12:01 PM
rscchembio.rsc.org
New in RSC Chemical Biology: SpyBLI — a fast, low-cost way to measure binding kinetics straight from crude samples. No purification, no cloning, data in under 24h. A game-changer for binder engineering!
DOI doi.org/10.1039/D5CB...
#ProteinEngineering #SpyBLI
July 18, 2025 at 2:53 PM
rscchembio.rsc.org
We're pleased to announce that Cecilie Mia Jørgensen (@ceciliejoergensen.bsky.social) has won the RSC Chem. Biol. and Org. Biomol. Chem. (@orgbiomolchem.rsc.org) poster award at the 2025 Peptide and Protein Science Group Early Stage Researcher Meeting! Please join us in congratulating Cecilie.
A photo of the winner receiving their award.
July 16, 2025 at 11:08 AM
rscchembio.rsc.org
Exciting news! Our Editorial Board member, Ali Tavassoli, has won the 2025 Interdisciplinary Prize! 🎉

Ali is being recognised for pioneering creating new approaches to target "undruggable" protein–protein interactions.

Check out Ali's work here 👉 doi.org/10.1039/C8SC...
June 26, 2025 at 10:04 AM
rscchembio.rsc.org
#ChemBioParis2025
🚨 Early Bird Registration & Abstract Submission CLOSES TOMORROW!

Register & send you abstract today!

📍 Sorbonne Université, Paris
📆 6-9 October, 2025

Register below 👇

🔗 lnkd.in/dpfzrSpX

#ICBS2025 #ECBS2025 #ChemBio
June 23, 2025 at 2:04 PM
rscchembio.rsc.org
The Early Stage Researcher Meeting 2025 at @unibirmingham.bsky.social is on July 10!
The @rsc-ppsg.bsky.social event includes oral presentations by PhD students, postdoc researchers, and a poster award session.

🗓️ Register by June 20
👉 https://bit.ly/3TsMCFK

#PPSG2025
June 17, 2025 at 4:00 PM
rscchembio.rsc.org
RSC Chemical Biology and Organic & Biomolecular Chemistry (@orgbiomolchem.rsc.org) are proud to support the 17th International Symposium on Biocatalysis and Biotransformations in Basel, 29 June-3 July 2025. Don't miss your opportunity to participate: www.biotrans2025.com
A banner listing the advantages of the meeting and its details
June 10, 2025 at 8:05 AM
rscchembio.rsc.org
🚨 It’s deadline day!
Submit your abstract for a talk or poster at #PPSG2025 by the end of today (5 June)!
We’d love to hear your work in protein/peptide science 🧬
🔗 www.rsc.org/events/d...

June 5, 2025 at 7:44 AM
rscchembio.rsc.org
🚨RSC Chemical Biology is online and #openaccess!

Cover: John Pezacki et al., "Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques"
👉Read: doi.org/10.1039/D4CB...

👉Meet our Emerging Investigators 2024: doi.org/10.1039/D5CB...
June 4, 2025 at 1:46 PM