RoseMarie Akiki
@rosemarieakiki.bsky.social
MD/PhD candidate at MUSC, molecular neuroscientist.
Étranger
Étranger
An honor to have such great mentors @makototaniguchi.bsky.social and Dr. Cowan! Very proud to be an alumna from their labs!
It was a wonderful day to celebrate an important milestone together.
Our student @rosemarieakiki.bsky.social did an excellent job on her defense!! Thank you to co-mentor, Dr. Chris Cowan, our lab members, and Dept. of Neuroscience for the warm support and encouragements!!
Our student @rosemarieakiki.bsky.social did an excellent job on her defense!! Thank you to co-mentor, Dr. Chris Cowan, our lab members, and Dept. of Neuroscience for the warm support and encouragements!!
April 8, 2025 at 1:36 AM
An honor to have such great mentors @makototaniguchi.bsky.social and Dr. Cowan! Very proud to be an alumna from their labs!
Reposted by RoseMarie Akiki
Our study, led by @rosemarieakiki.bsky.social, reveals how long non-coding RNAs translate emotional experience into immediate early gene expression through R-loops and 3D chromatin loops.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A long noncoding eRNA forms R-loops to shape emotional experience–induced behavioral adaptation
Emotional experiences often evoke neural plasticity that supports adaptive changes in behavior, including maladaptive plasticity associated with mood and substance use disorders. These adaptations are...
www.science.org
April 8, 2025 at 1:11 AM
Our study, led by @rosemarieakiki.bsky.social, reveals how long non-coding RNAs translate emotional experience into immediate early gene expression through R-loops and 3D chromatin loops.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Check out our commentary on Mitra et al.'s findings in Biological Psychiatry on an epigenetic mechanism promoting heroine relapse after prolonged abstinence www.sciencedirect.com/science/arti...
An Epigenetic Mechanism Promoting Heroin Relapse After Prolonged Abstinence
www.sciencedirect.com
March 18, 2025 at 4:24 PM
Check out our commentary on Mitra et al.'s findings in Biological Psychiatry on an epigenetic mechanism promoting heroine relapse after prolonged abstinence www.sciencedirect.com/science/arti...
I owe it all to Lebanon ❤️
"My memories of Lebanon and the resilience of its people strengthened my resolve."
This week's #ScienceWorkingLife: https://scim.ag/3C2dtnd
This week's #ScienceWorkingLife: https://scim.ag/3C2dtnd
January 20, 2025 at 7:08 PM
I owe it all to Lebanon ❤️
Reposted by RoseMarie Akiki
Noncoding RNA controls the expression of a gene implicated in drug- and stress-induced behaviors.
Learn more in a new #SciencePerspective:
Learn more in a new #SciencePerspective:
A neuronal gene that loops the loop
Noncoding RNA controls the expression of a gene implicated in drug- and stress-induced behaviors
scim.ag
December 27, 2024 at 7:56 PM
Noncoding RNA controls the expression of a gene implicated in drug- and stress-induced behaviors.
Learn more in a new #SciencePerspective:
Learn more in a new #SciencePerspective:
It's like someone read my mind!
Molecular basis of behavioral changes. There goes your free will. #biology #emotion #behavior https://www.science.org/doi/abs/10.1126/science.adp1562
December 14, 2024 at 9:08 PM
It's like someone read my mind!
Reposted by RoseMarie Akiki
A genetic regulatory mechanism involving RNA:DNA structures plays a crucial role in behavioral adaptations to emotional experiences, potentially informing RNA-based therapies for psychiatric disorders. doi.org/g8vf5f
RNA:DNA 'sandwich' plays key role in behavioral adaptations arising from emotional experiences, research reveals
A team of neuroscience researchers at the Medical University of South Carolina reports in Science the discovery of a new genetic regulatory mechanism involved in behavioral adaptations to emotional experiences in a preclinical model.
medicalxpress.com
December 12, 2024 at 7:02 PM
A genetic regulatory mechanism involving RNA:DNA structures plays a crucial role in behavioral adaptations to emotional experiences, potentially informing RNA-based therapies for psychiatric disorders. doi.org/g8vf5f
Reposted by RoseMarie Akiki
Following @daylab.bsky.social’s nice paper on eRNA regulating Fos, and then our paper showing eRNA mediated regulation of NR4A2, here’s yet another eRNA controlling NPAS4.
LncRNAs for the win in the brain!
www.science.org/doi/10.1126/...
LncRNAs for the win in the brain!
www.science.org/doi/10.1126/...
A long noncoding eRNA forms R-loops to shape emotional experience–induced behavioral adaptation
Emotional experiences often evoke neural plasticity that supports adaptive changes in behavior, including maladaptive plasticity associated with mood and substance use disorders. These adaptations are...
www.science.org
December 12, 2024 at 10:34 PM
Following @daylab.bsky.social’s nice paper on eRNA regulating Fos, and then our paper showing eRNA mediated regulation of NR4A2, here’s yet another eRNA controlling NPAS4.
LncRNAs for the win in the brain!
www.science.org/doi/10.1126/...
LncRNAs for the win in the brain!
www.science.org/doi/10.1126/...
Great perspective on our paper by Dr. Heller looping our findings to modern molecular neuroscience!
It's my pleasure to share our perspective on phenomenal new research out from Rose Akiki in the Cowan and Taniguchi labs.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A neuronal gene that loops the loop
Noncoding RNA controls the expression of a gene implicated in drug- and stress-induced behaviors
www.science.org
December 14, 2024 at 12:43 AM
Great perspective on our paper by Dr. Heller looping our findings to modern molecular neuroscience!