Romberg Lab
@romberglab.bsky.social
Solving immunologic mysteries at UPenn and CHOP since 2015
www.romberglab.org
www.romberglab.org
Pinned
Romberg Lab
@romberglab.bsky.social
· May 30
🚨New Paper Alert🚨
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
Re-watching The Office with my kids…realizing my PI leadership style is very Michael Scott…. Pray for me
a man in a suit and tie stands in front of a framed certificate that says ' award ' on it
ALT: a man in a suit and tie stands in front of a framed certificate that says ' award ' on it
media.tenor.com
November 5, 2025 at 12:28 AM
Re-watching The Office with my kids…realizing my PI leadership style is very Michael Scott…. Pray for me
Our recent work describing extreme enrichment of complement factor I deficiency in the Amish from @jacionline.bsky.social was featured on the front page of the Philadelphia Inquirer (@inquirer.com). Above the fold (and the Eagles!).
(static1.squarespace.com/static/65273...)
(static1.squarespace.com/static/65273...)
August 26, 2025 at 1:52 PM
Our recent work describing extreme enrichment of complement factor I deficiency in the Amish from @jacionline.bsky.social was featured on the front page of the Philadelphia Inquirer (@inquirer.com). Above the fold (and the Eagles!).
(static1.squarespace.com/static/65273...)
(static1.squarespace.com/static/65273...)
Another immune masterclass in @jhumimmunity.org. This journal is on a tear!
Tobin and @macattacklab.bsky.social review #InbornErrorsOfImmunity that can present with rheumatologic and #autoimmune complications and the role of genetic testing for establishing a molecular diagnosis & devising personalized treatment plans to improve patient outcomes. rupress.org/jhi/article/...
July 23, 2025 at 7:21 PM
Another immune masterclass in @jhumimmunity.org. This journal is on a tear!
Reposted by Romberg Lab
.@alneehus.bsky.social, @romberglab.bsky.social and @bloodgenes.bsky.social review how genetic variation impacts early B cell development, & discuss inherited rare variants & more common polymorphisms that predispose to B cell-related immune disorders & malignancies rupress.org/jhi/article/...
June 25, 2025 at 4:12 PM
.@alneehus.bsky.social, @romberglab.bsky.social and @bloodgenes.bsky.social review how genetic variation impacts early B cell development, & discuss inherited rare variants & more common polymorphisms that predispose to B cell-related immune disorders & malignancies rupress.org/jhi/article/...
Nice commentary by the one and only Stu Tangye in Blood hyping our recent paper on PU.1 agammaglobulinemia.
www.romberglab.org
June 15, 2025 at 1:22 AM
Nice commentary by the one and only Stu Tangye in Blood hyping our recent paper on PU.1 agammaglobulinemia.
Reposted by Romberg Lab
PU.1 haploinsufficiency causes agammaglobulinemia and dendritic-cell deficiencies with incomplete penetrance and variable expressivity. buff.ly/itn0zjd #hemesky #immunobiologandimmunotherapy
May 30, 2025 at 4:04 PM
PU.1 haploinsufficiency causes agammaglobulinemia and dendritic-cell deficiencies with incomplete penetrance and variable expressivity. buff.ly/itn0zjd #hemesky #immunobiologandimmunotherapy
🚨New Paper Alert🚨
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
May 30, 2025 at 1:13 AM
🚨New Paper Alert🚨
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
Now out in @bloodjournal.bsky.social
We scoured the ends of the earth for rare human PU.1 variants and subjected 134 of them to suite of functional assessments.
Reposted by Romberg Lab
Interested in translational human immunology? We are currently recruiting a PhD student or a post-doc to work on an exciting project to to study immune changes leading to the development of type 1 diabetes. #immunosky #sciencejobs uef.varbi.com/en/what:job/...
Postdoctoral Researcher/Doctoral Researcher/Project Researcher, Translational Immunology
The University of Eastern Finland is inviting applications for a Postdoctoral Researcher/Doctoral Researcher/Project Researcher (Translational Immunology) position in Kuopio. The position will be fill
uef.varbi.com
May 23, 2025 at 5:38 AM
Interested in translational human immunology? We are currently recruiting a PhD student or a post-doc to work on an exciting project to to study immune changes leading to the development of type 1 diabetes. #immunosky #sciencejobs uef.varbi.com/en/what:job/...
Reposted by Romberg Lab
In @jhumimmunity.org, Hajjar et al. identify distinct gut #microbiome profiles in common variable #immunodeficiency patients with noninfectious complications and establish a novel germ-free mouse model using fecal microbiota transplant. rupress.org/jhi/article/...
April 24, 2025 at 8:41 PM
In @jhumimmunity.org, Hajjar et al. identify distinct gut #microbiome profiles in common variable #immunodeficiency patients with noninfectious complications and establish a novel germ-free mouse model using fecal microbiota transplant. rupress.org/jhi/article/...
At last!
The first JHI articles are online! Poli et al present the 2024 update of the @iuis-online.bsky.social classification of #InbornErrorsOfImmunity (rupress.org/jhi/article/...) & Bousfiha et al provide an accompanying phenotypic classification to assist clinical diagnoses (rupress.org/jhi/article/...)
April 15, 2025 at 8:22 PM
At last!
Reposted by Romberg Lab
JHI Associate Editor Neil Romberg @romberglab.bsky.social is an Associate Professor at the University of Pennsylvania, with a special interest in humoral immunity.
Learn more about JHI 📗 https://buff.ly/42FXtBZ
Learn more about JHI 📗 https://buff.ly/42FXtBZ
February 24, 2025 at 3:17 PM
JHI Associate Editor Neil Romberg @romberglab.bsky.social is an Associate Professor at the University of Pennsylvania, with a special interest in humoral immunity.
Learn more about JHI 📗 https://buff.ly/42FXtBZ
Learn more about JHI 📗 https://buff.ly/42FXtBZ
Reposted by Romberg Lab
Immune response to co-administration of bovine tuberculosis and contraceptive vaccines in badgers (Meles meles) https://www.biorxiv.org/content/10.1101/2025.02.12.637632v1
February 16, 2025 at 7:16 AM
Immune response to co-administration of bovine tuberculosis and contraceptive vaccines in badgers (Meles meles) https://www.biorxiv.org/content/10.1101/2025.02.12.637632v1
Reposted by Romberg Lab
Grateful to see @retractionwatch.com share our story! Learn more about the launch of Journal of Human Immunity, why our editors made the move, and what’s next for our nonprofit journal with @rupress.org. Insights from our EiC @casanovalab.bsky.social here: retractionwatch.com/2025/02/06/e...
Editors resign from Springer immunology journal to launch nonprofit title
Several top editors of the Journal of Clinical Immunology, a Springer Nature title, have jumped ship to start a new, nonprofit journal with Rockefeller University Press. Jean-Laurent Casanova…
retractionwatch.com
February 6, 2025 at 8:36 PM
Grateful to see @retractionwatch.com share our story! Learn more about the launch of Journal of Human Immunity, why our editors made the move, and what’s next for our nonprofit journal with @rupress.org. Insights from our EiC @casanovalab.bsky.social here: retractionwatch.com/2025/02/06/e...
Reposted by Romberg Lab
Welcome to the future of #HumanImmunity research! @rupress.org and the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) are launching the Journal of Human Immunity (JHI)! Stay tuned for groundbreaking, #OpenAccess research! 👉 https://buff.ly/4ajqm8W
January 16, 2025 at 4:00 PM
Welcome to the future of #HumanImmunity research! @rupress.org and the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) are launching the Journal of Human Immunity (JHI)! Stay tuned for groundbreaking, #OpenAccess research! 👉 https://buff.ly/4ajqm8W
Reposting the IEI starter pack as there are new additions!
December 24, 2024 at 6:54 PM
Reposting the IEI starter pack as there are new additions!
Here’s to all the abnormal normals out there…range life
Imagine your 🩸test results compared not to a ‘standard reference range’, but to your own values as well.
Some reference ranges are based on an archaic, primarily Caucasian reference. Misserves some demographics. Ferritin is an example, 📈in Asians.
#PersonalizedMed
www.nature.com/articles/d41...
Some reference ranges are based on an archaic, primarily Caucasian reference. Misserves some demographics. Ferritin is an example, 📈in Asians.
#PersonalizedMed
www.nature.com/articles/d41...
Personalized ranges for blood-test results enable precision diagnostics
Benefits of tracking if a person’s results differ from their setpoints.
www.nature.com
December 15, 2024 at 1:48 AM
Here’s to all the abnormal normals out there…range life
Romberg Lab Merch alert! This year’s frosted mug rates just above the Romberg Lab Softball T-shirt and just below the Romberg Lab Fanny Pack (aka the GOAT).
www.romberglab.org/merch-store
www.romberglab.org/merch-store
December 7, 2024 at 11:17 PM
Romberg Lab Merch alert! This year’s frosted mug rates just above the Romberg Lab Softball T-shirt and just below the Romberg Lab Fanny Pack (aka the GOAT).
www.romberglab.org/merch-store
www.romberglab.org/merch-store
🦠🔥
The purpose of schools, from the following perspectives:
Parents: a safe place for education of kids, to give them the foundation for opportunities.
Children: fun with friends but homework 👎🏼
Viruses: PARTY! PARTY! PARTY!
Parents: a safe place for education of kids, to give them the foundation for opportunities.
Children: fun with friends but homework 👎🏼
Viruses: PARTY! PARTY! PARTY!
December 5, 2024 at 1:07 PM
🦠🔥
December 4, 2024 at 9:49 AM