The Rokas Lab at Vanderbilt University
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rokaslab.bsky.social
The Rokas Lab at Vanderbilt University
@rokaslab.bsky.social
The Laboratory of Antonis Rokas at Vanderbilt University. Tweets should be interpreted as bookmarks, not as endorsements. All opinions are Antonis'.

http://www.rokaslab.org
Reposted by The Rokas Lab at Vanderbilt University
NEW pub in @science.org 🥳

Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?

For over 15 years, #phylogenomic studies have been divided.

We provide new evidence suggesting that...

🔗: www.science.org/doi/10.1126/...
November 13, 2025 at 8:34 PM
Reposted by The Rokas Lab at Vanderbilt University
Excited to share our latest paper led by Ph.D. Candidate, Owen Hale, titled Elevated rates and Biased Spectra of Mutations in Anaerobically Cultured Lactic Acid Bacteria out now in mBio!

journals.asm.org/doi/10.1128/...
Elevated rates and biased spectra of mutations in anaerobically cultured lactic acid bacteria | mBio
Despite Earth’s oxygen-free origins and the abundance of microorganisms that thrive without oxygen, little is known about the rates and patterns of mutations in anaerobic species. This study directly ...
journals.asm.org
November 13, 2025 at 12:36 PM
Abstract submission open for #Fungal26 through Dec 4! Comparative & functional genomics, gene regulation, cell biology, biochemistry and metabolism, population & evolutionary genetics, host-pathogen interactions, ecology, and more. Can’t wait to see your science!
genetics-gsa.org/fungal-2026/...
November 12, 2025 at 10:47 PM
Reposted by The Rokas Lab at Vanderbilt University
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...
shorturl.at
November 12, 2025 at 8:34 PM
Reposted by The Rokas Lab at Vanderbilt University
With @linder-surprise.bsky.social and the @rokaslab.bsky.social, we recently expanded upon an analysis where glucose uptake rates were inversely correlated with the cell surface area-to-volume ratio, testing 282 species in the Saccharomycotina yeast subphylum.
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 11, 2025 at 4:38 PM
Reposted by The Rokas Lab at Vanderbilt University
New work led by members of the @rokaslab.bsky.social! ☺️ 1,154 yeast genomes in the Saccharomycotina subphylum were surveyed for their relationship between reduced gene repertoires broadly associated with genome stability functions and elevated evolutionary rates.🧬
academic.oup.com/mbe/advance-...
Stable hypermutators revealed by the genomic landscape of genes involved in genome stability among yeast species
Abstract. Mutator phenotypes are short-lived due to the rapid accumulation of deleterious mutations. Yet, recent observations reveal that certain fungi can
academic.oup.com
November 11, 2025 at 4:51 PM
Reposted by The Rokas Lab at Vanderbilt University
My book 'The Tree of Life' is published in the USA and Canada today.

Available as book, on kindle and as audio.

I would be really grateful for reposts.

www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
November 11, 2025 at 12:01 PM
Reposted by The Rokas Lab at Vanderbilt University
Mini @rokaslab.bsky.social reunion with Dr. Abigail Lind @abigailllind.bsky.social

Amazing seminar... What is in our gut and what is it doing!?

I assume our students are flocking to try EukDetect!
November 7, 2025 at 7:40 PM
Reposted by The Rokas Lab at Vanderbilt University
Pleased to share our preprint which builds off of recent work connecting glucose uptake rates and cell morphology across yeast species:

www.biorxiv.org/content/10.1...
www.biorxiv.org
November 6, 2025 at 3:05 PM
Reposted by The Rokas Lab at Vanderbilt University
Welsey Roberts presents his evidence that teaching #evolution works and it doesn't have to be religion OR evolution. @ncse.bsky.social #teaching #scicomm
November 4, 2025 at 2:56 PM
Reposted by The Rokas Lab at Vanderbilt University
NEW Publication🥳

Rapid #evolution is thought to be disadvantageous due to the accumulation of deleterious #mutations. We identify multiple lineages of rapidly evolving and stable #yeast that are many millions of years old

🔗: academic.oup.com/mbe/advance-...
November 3, 2025 at 6:29 PM
Reposted by The Rokas Lab at Vanderbilt University
We just joined Southern Hemisphere efforts and co-authored a review on yeast research from this side of the world 🌎 Turns out, there’s a lot to tell—and much more to come! Huge thanks to Varela’s team and @pablo-villa.bsky.social for the great collaboration 🍻

academic.oup.com/femsyr/artic...
The Southern Hemisphere yeast frontier: from nature dwellers to accomplished fermenters
This mini-review discusses the different yeast species found in the Southern Hemisphere.
academic.oup.com
October 30, 2025 at 11:50 PM
Reposted by The Rokas Lab at Vanderbilt University
Check out our newest issue where we interview Antonis Rokas, who uses DNA data from fungi, animals, and plants to study the patterns and processes of evolutionary diversity at Vanderbilt University. @rokaslab.bsky.social www.cell.com/current-biol...
Q & A
Interview with Antonis Rokas, who uses DNA data from fungi, animals, and plants to study the patterns and processes of evolutionary diversity at Vanderbilt University.
www.cell.com
October 31, 2025 at 2:56 PM
Registrations and abstract submissions are now open for the always stellar #fungal #genetics conference at lovely Asilomar, CA - March 17-22, 2026. Thank you to @genetics-gsa.bsky.social for the amazing partnership with the fungal community. Hope to see you there!
October 31, 2025 at 6:44 PM
Reposted by The Rokas Lab at Vanderbilt University
I built a small app (GenomeCheck ✅ - github.com/meadm/Genome...) for assessing genome assemblies and catching mislabeled data. It can be run on Streamlit Community Cloud (genomecheck.streamlit.app), Docker (meadm/genomecheck:latest), or locally via the GitHub repo. Let me know what you think!
GitHub - meadm/GenomeCheck: Streamlit app within a docker container for carrying out genome QC and comparisons
Streamlit app within a docker container for carrying out genome QC and comparisons - meadm/GenomeCheck
github.com
October 30, 2025 at 5:13 PM
Reposted by The Rokas Lab at Vanderbilt University
Look at how cute this town is where the workshop will be bsky.app/profile/jlst...
October 29, 2025 at 7:26 PM
Great workshop, fantastic location, amazing instructors! If you are interested in obtaining advanced training in phylogenomics / comparative genomics research, apply now!
October 29, 2025 at 7:49 PM
Reposted by The Rokas Lab at Vanderbilt University
To commemorate the 100th Anniversary of the landmark Scopes “Monkey" Trial, we’ve created a special quiz to test your knowledge! This historic trial sparked a national conversation about science, education, and the role of evolution in the classroom. ncse.ngo/scopes-monke... #Scopes100 #trivia
Scopes "Monkey" Trial Quiz | National Center for Science Education
To commemorate the 100th anniversary of the Scopes "Monkey" Trial, NCSE has developed a quiz to help you test your knowledge of this pivotal event. When you're done with the quiz, you can check out mo...
ncse.ngo
October 29, 2025 at 2:54 PM
Reposted by The Rokas Lab at Vanderbilt University
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
October 12, 2025 at 2:20 PM
Reposted by The Rokas Lab at Vanderbilt University
Want to understand how entire fungal chromosomes can be horizontally transferred?
Join us to unravel the mechanism/consequences of horizontal chromosome transfer in a fungal pathogen as part of an ERC-funded project. Postdoc/PhD positions available.
fungal-evolutionary-genetics.de/open-positio...
Open Positions
ERC-funded project on the mechanism of horizontal transfer of entire fungal chromosomes PhD PostDoc
fungal-evolutionary-genetics.de
October 13, 2025 at 9:39 AM
Reposted by The Rokas Lab at Vanderbilt University
We had an amazing @official-smbe.bsky.social satellite meeting in Puerto Varas. Great science, colleagues & Patagonian experience. Thanks the organizers @pablo-villa.bsky.social et al & SMBE for putting this together!
October 10, 2025 at 11:46 AM
Reposted by The Rokas Lab at Vanderbilt University
If you saw my talk on the population structure of #Aspergillus flavus at Fungal Genetics in 2024, you might have heard someone ask "how does Aspergillus oryzae fit into the picture?"
If so, you heard my answer was "wait and see--we're working on this exact topic"
Well, the wait is over! Preprint ⬇️
Population-Specific Transcriptomic Shifts Underlie Secondary Metabolic Diversification in Aspergillus flavus and the Domestication of Aspergillus oryzae https://www.biorxiv.org/content/10.1101/2025.10.02.680074v1
October 7, 2025 at 7:50 PM
Reposted by The Rokas Lab at Vanderbilt University
What started as a project characterizing variation in metabolic rates across yeasts turned into an interesting story about convergent evolution acting on the same key genes through distinct molecular mechanisms with @hittingerlab.bsky.social & @rokaslab.bsky.social.

www.biorxiv.org/content/10.1...
Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes
As the tree of life becomes increasingly accessible to molecular investigations, describing mechanisms underlying evolutionary convergence and constraint will be crucial to understanding diversificati...
www.biorxiv.org
October 6, 2025 at 5:18 PM