Robles Lab
@robles-lab.bsky.social
Systems Chronobiology laboratory at LMU, Munich
Circadian clocks ⏰ || Sleep 💤|| MS-based quantitative proteomics
https://www.med.lmu.de/imp/en/research-groups/robles-lab-sytems-chronobiology/
Circadian clocks ⏰ || Sleep 💤|| MS-based quantitative proteomics
https://www.med.lmu.de/imp/en/research-groups/robles-lab-sytems-chronobiology/
Reposted by Robles Lab
Proud moment to see work from my PhD in the @granadalab.bsky.social featured on the cover of the April 2025 issue of @molsystbiol.org 🥹 special thanks to my talented husband who helped design this cover. Check out the full paper here: lnkd.in/eDVQuRfc.
April 4, 2025 at 10:54 AM
Proud moment to see work from my PhD in the @granadalab.bsky.social featured on the cover of the April 2025 issue of @molsystbiol.org 🥹 special thanks to my talented husband who helped design this cover. Check out the full paper here: lnkd.in/eDVQuRfc.
Congratulations to @immunothrombosis.bsky.social and Afra! We are glad for our little contribution.
7/x Using the PF4Cre-iDTR mouse, we created platelet cohorts of similar age using Diphtheria toxin application in this mouse line, and performed shotgun proteomics. This revealed clear separation of aged and young platelets with regards to proteome.
January 25, 2025 at 9:09 AM
Congratulations to @immunothrombosis.bsky.social and Afra! We are glad for our little contribution.
Reposted by Robles Lab
Only last week I spent two hours with a journalist emphasising this concept: expecting everyone to sleep 8 hours is like expecting everyone to wear the same shoe size. That's not how biology works.
www.scientificamerican.com/article/why-...
www.scientificamerican.com/article/why-...
Not Everyone May Need Eight Hours of Sleep
Short sleepers cruise by on four to six hours a night and don’t seem to suffer ill effects. Turns out they’re genetically built to require less sleep than the rest of us
www.scientificamerican.com
December 23, 2024 at 10:24 AM
Only last week I spent two hours with a journalist emphasising this concept: expecting everyone to sleep 8 hours is like expecting everyone to wear the same shoe size. That's not how biology works.
www.scientificamerican.com/article/why-...
www.scientificamerican.com/article/why-...
Reposted by Robles Lab
ICYMI 💡 This @pnas.org essay from July discusses a critical #confound in experiments on animals. 🕰️ Time-of-day matters, but it is rarely addressed in experimental design or reported in published papers. By Nelson, DeVries, & Prendergast.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Researchers need to better address time-of-day as a critical biological variable | PNAS
Researchers need to better address time-of-day as a critical biological variable
www.pnas.org
December 16, 2024 at 12:33 PM
ICYMI 💡 This @pnas.org essay from July discusses a critical #confound in experiments on animals. 🕰️ Time-of-day matters, but it is rarely addressed in experimental design or reported in published papers. By Nelson, DeVries, & Prendergast.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Robles Lab
Excited to share our latest article! We find that the brain tumor Glioblastoma has a circadian clock that syncs with its host’s environment. These tumors also hijack the circadian clock and use daily signals, like glucocorticoids, to grow 🧠⏱️ @erikherzog.bsky.social
More: www.cell.com/cancer-cell/...
More: www.cell.com/cancer-cell/...
Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host
Gonzalez-Aponte et al. identify daily glucocorticoid receptor signaling as an intrinsic driver of glioblastoma (GBM) progression and a synchronizer of tumor clock gene expression to the host. This work provides an intrinsic circadian driver, and therapeutic target, to slow GBM growth, and offers considerations for glucocorticoid use in the clinic.
www.cell.com
December 12, 2024 at 4:48 PM
Excited to share our latest article! We find that the brain tumor Glioblastoma has a circadian clock that syncs with its host’s environment. These tumors also hijack the circadian clock and use daily signals, like glucocorticoids, to grow 🧠⏱️ @erikherzog.bsky.social
More: www.cell.com/cancer-cell/...
More: www.cell.com/cancer-cell/...
Reposted by Robles Lab
If you just moved to BlueSky and interested in #chronobiology, find some of your community here!
Want to be added? Reply with evidence your work relates to chronobiology.
go.bsky.app/Sw8L4aS
With all the new people coming over, I’ll repost weekly for the next month or so.
🧪 🌍 🦑 #EvoBio
Want to be added? Reply with evidence your work relates to chronobiology.
go.bsky.app/Sw8L4aS
With all the new people coming over, I’ll repost weekly for the next month or so.
🧪 🌍 🦑 #EvoBio
November 25, 2024 at 4:33 PM
If you just moved to BlueSky and interested in #chronobiology, find some of your community here!
Want to be added? Reply with evidence your work relates to chronobiology.
go.bsky.app/Sw8L4aS
With all the new people coming over, I’ll repost weekly for the next month or so.
🧪 🌍 🦑 #EvoBio
Want to be added? Reply with evidence your work relates to chronobiology.
go.bsky.app/Sw8L4aS
With all the new people coming over, I’ll repost weekly for the next month or so.
🧪 🌍 🦑 #EvoBio