Rasmus Hartmann-Petersen
@rhp-lab.bsky.social
Professor at the Linderstrøm-Lang Centre for Protein Science, University of Copenhagen.
Interests: Protein Quality Control, Genetics, Molecular Chaperones, Degrons.
Interests: Protein Quality Control, Genetics, Molecular Chaperones, Degrons.
Reposted by Rasmus Hartmann-Petersen
Martin Grønbæk-Thygesen in @rhp-lab.bsky.social measured abundance and toxicity (both independently of function) of missense variants in aspartoacylase, and found that a subset of the low-abundance variants were toxic, induced a stress response which correlated with toxicity
doi.org/10.1038/s414...
doi.org/10.1038/s414...
September 19, 2025 at 8:57 PM
Martin Grønbæk-Thygesen in @rhp-lab.bsky.social measured abundance and toxicity (both independently of function) of missense variants in aspartoacylase, and found that a subset of the low-abundance variants were toxic, induced a stress response which correlated with toxicity
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Rasmus Hartmann-Petersen
... wait! There's more great Review content!
☘️ mechanisms of #SAM homeostasis (Ben Tu et al)
☘️ glucose sensing by #glucokinase and how disease variants impact its function @sarahgersing.bsky.social @lindorfflarsen.bsky.social @rhp-lab.bsky.social
☘️ mechanisms of #SAM homeostasis (Ben Tu et al)
☘️ glucose sensing by #glucokinase and how disease variants impact its function @sarahgersing.bsky.social @lindorfflarsen.bsky.social @rhp-lab.bsky.social
March 6, 2025 at 4:43 PM
... wait! There's more great Review content!
☘️ mechanisms of #SAM homeostasis (Ben Tu et al)
☘️ glucose sensing by #glucokinase and how disease variants impact its function @sarahgersing.bsky.social @lindorfflarsen.bsky.social @rhp-lab.bsky.social
☘️ mechanisms of #SAM homeostasis (Ben Tu et al)
☘️ glucose sensing by #glucokinase and how disease variants impact its function @sarahgersing.bsky.social @lindorfflarsen.bsky.social @rhp-lab.bsky.social