Richard Held
@rgsheld.bsky.social
Neuroscientist / synaptic physiologist interested in protein topography and cellular signal transduction. Ephys in the past, cryoET now, mouse genetics forever.
https://scholar.google.com/citations?hl=en&user=ESpBK1AAAAAJ
https://scholar.google.com/citations?hl=en&user=ESpBK1AAAAAJ
Check out a recent preprint here:
www.biorxiv.org/content/10.1...
We used GluA2 knock-in mice localize synaptic AMPARs, revealing an 'exclusion zone' relationship between synaptic vesicles and clustered AMPARs and the in-situ structure of the scaffolding interaction between AMPARs and PSD-95.
www.biorxiv.org/content/10.1...
We used GluA2 knock-in mice localize synaptic AMPARs, revealing an 'exclusion zone' relationship between synaptic vesicles and clustered AMPARs and the in-situ structure of the scaffolding interaction between AMPARs and PSD-95.
November 13, 2024 at 6:06 PM
Check out a recent preprint here:
www.biorxiv.org/content/10.1...
We used GluA2 knock-in mice localize synaptic AMPARs, revealing an 'exclusion zone' relationship between synaptic vesicles and clustered AMPARs and the in-situ structure of the scaffolding interaction between AMPARs and PSD-95.
www.biorxiv.org/content/10.1...
We used GluA2 knock-in mice localize synaptic AMPARs, revealing an 'exclusion zone' relationship between synaptic vesicles and clustered AMPARs and the in-situ structure of the scaffolding interaction between AMPARs and PSD-95.
Reintro: I'm a neuroscientist interested in how cells use molecular topography to control signal transduction. I use #CryoET and mouse genetic tools to map the topography of synaptic proteins and determine in-situ structures of scaffolding interactions that control said topography.
November 13, 2024 at 6:06 PM
Reintro: I'm a neuroscientist interested in how cells use molecular topography to control signal transduction. I use #CryoET and mouse genetic tools to map the topography of synaptic proteins and determine in-situ structures of scaffolding interactions that control said topography.