Rezwan Siddiquee
@rezwansiddiquee.bsky.social
PhD Candidate in Synthetic Biology #seekRNA #proteins
@Sydney_Uni. Other half of @taylorszyszka
https://scholar.google.com/citations?hl=en&user=nZ8TDHcAAAAJ
@Sydney_Uni. Other half of @taylorszyszka
https://scholar.google.com/citations?hl=en&user=nZ8TDHcAAAAJ
Pinned
High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
Cargo-filled protein cages are powerful tools in biotechnology with demonstrated potential as catalytic nanoreactors and vehicles for targeted drug delivery. While endogenous biomolecules can be packa...
www.biorxiv.org
Very excited to share our new pre-print! We’ve developed a new way to put any type of cargo (biological or synthetic) into protein cages! All in-vitro! This enables massively scalable in vitro packaging technology for multiple lucrative applications. www.biorxiv.org/content/10.1...
Reposted by Rezwan Siddiquee
Every hear of Vaults? If not, read this preprint! New from the lab, exploring novel mechanisms of RNA trafficking in neurons and what they might mean for memory. Led by stellar PhD student Mason Musgrove. #RNAsky
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Dynamic regulation of neuronal Vault trafficking and RNA cargo by the noncoding RNA, Vaultrc5
Vaults are large ribonucleoprotein complexes of unknown function in neurons. Here, we report that the Vault-associated noncoding RNA, Vaultrc5, is highly enriched at the synapse and is required for ac...
www.biorxiv.org
May 19, 2025 at 4:22 AM
Every hear of Vaults? If not, read this preprint! New from the lab, exploring novel mechanisms of RNA trafficking in neurons and what they might mean for memory. Led by stellar PhD student Mason Musgrove. #RNAsky
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Rezwan Siddiquee
Congrats to @taylorszyszka.bsky.social and @rezwansiddiquee.bsky.social who have been invited to Raise the Bar! 20 academics will visit 10 bars across Sydney to talk about their research, for 1 night only.
📅 Thu 3 April, 7:30 PM
📍Bank Hotel, 324 King St, Newtown
🎟️ Register: bit.ly/43Ci7n0
#RTBSYD
📅 Thu 3 April, 7:30 PM
📍Bank Hotel, 324 King St, Newtown
🎟️ Register: bit.ly/43Ci7n0
#RTBSYD
March 11, 2025 at 11:57 PM
Congrats to @taylorszyszka.bsky.social and @rezwansiddiquee.bsky.social who have been invited to Raise the Bar! 20 academics will visit 10 bars across Sydney to talk about their research, for 1 night only.
📅 Thu 3 April, 7:30 PM
📍Bank Hotel, 324 King St, Newtown
🎟️ Register: bit.ly/43Ci7n0
#RTBSYD
📅 Thu 3 April, 7:30 PM
📍Bank Hotel, 324 King St, Newtown
🎟️ Register: bit.ly/43Ci7n0
#RTBSYD
Really proud of the famous Taylor Szyszka for the perseverance for this project! Amazing work!
Light-ning Talks #LorneProteins2025 Taylor Szyszka Engineering carbon-fixing protein cages. Carboxysomes are great, but encapsulins can assemble a uniform cage around any target tagged with a cargo peptide at C term. 42 nm across. Carboxysome mimic with encapsulin? Encapsulating rubisco.
February 11, 2025 at 10:38 PM
Really proud of the famous Taylor Szyszka for the perseverance for this project! Amazing work!
Had such a wonderful time at #Coesb2024! Got to meet like minded synthetic biologists and learn about their successes and challenges. And huge thanks to @ARC_CoESB for an award for Outreach Excellence!
December 6, 2024 at 3:04 AM
Had such a wonderful time at #Coesb2024! Got to meet like minded synthetic biologists and learn about their successes and challenges. And huge thanks to @ARC_CoESB for an award for Outreach Excellence!
Reposted by Rezwan Siddiquee
My first ever Bluesky post is a new #preprint alert! What if we could put *anything* into a protein cage? Our new in vitro encapsulin assembly system is esay to use and enables the pacakging of protein and synthetic cargo!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
Cargo-filled protein cages are powerful tools in biotechnology with demonstrated potential as catalytic nanoreactors and vehicles for targeted drug delivery. While endogenous biomolecules can be packa...
www.biorxiv.org
November 27, 2024 at 12:49 AM
My first ever Bluesky post is a new #preprint alert! What if we could put *anything* into a protein cage? Our new in vitro encapsulin assembly system is esay to use and enables the pacakging of protein and synthetic cargo!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
This is a great tool to search for your community and quickly follow a bunch of people!
November 26, 2024 at 5:48 AM
This is a great tool to search for your community and quickly follow a bunch of people!
Reposted by Rezwan Siddiquee
I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅
#sciart #blender3d #biocatalysis
#sciart #blender3d #biocatalysis
November 25, 2024 at 5:14 PM
I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅
#sciart #blender3d #biocatalysis
#sciart #blender3d #biocatalysis
Very excited to share our new pre-print! We’ve developed a new way to put any type of cargo (biological or synthetic) into protein cages! All in-vitro! This enables massively scalable in vitro packaging technology for multiple lucrative applications. www.biorxiv.org/content/10.1...
High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
Cargo-filled protein cages are powerful tools in biotechnology with demonstrated potential as catalytic nanoreactors and vehicles for targeted drug delivery. While endogenous biomolecules can be packa...
www.biorxiv.org
November 26, 2024 at 5:32 AM
Very excited to share our new pre-print! We’ve developed a new way to put any type of cargo (biological or synthetic) into protein cages! All in-vitro! This enables massively scalable in vitro packaging technology for multiple lucrative applications. www.biorxiv.org/content/10.1...
Reposted by Rezwan Siddiquee
Long time lurker, first time poster... announcing our latest preprint on encapsulin protein cages!
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 26, 2024 at 4:12 AM
Long time lurker, first time poster... announcing our latest preprint on encapsulin protein cages!
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...