Rezwan Siddiquee
@rezwansiddiquee.bsky.social
PhD Candidate in Synthetic Biology #seekRNA #proteins
@Sydney_Uni. Other half of @taylorszyszka
https://scholar.google.com/citations?hl=en&user=nZ8TDHcAAAAJ
@Sydney_Uni. Other half of @taylorszyszka
https://scholar.google.com/citations?hl=en&user=nZ8TDHcAAAAJ
Check out Yu Heng’s post below.
bsky.app/profile/yuhe...
bsky.app/profile/yuhe...
Long time lurker, first time poster... announcing our latest preprint on encapsulin protein cages!
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...
We can now assemble them beautifully in vitro, without the ugly defects you get using acid/base or denaturants.
This lets us put any synthetic cargo into these cages.
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 26, 2024 at 5:32 AM
Check out Yu Heng’s post below.
bsky.app/profile/yuhe...
bsky.app/profile/yuhe...
This work is led by my better half, the superstar @taylorszyszka.bsky.social and is our first paper together! Many thanks to our supervisor @yuhenglau.bsky.social for incredible support and of course, from contributors Alex, Lachlan, Regi, Titus and collaborators Andrew and Claire from UTS.
November 26, 2024 at 5:32 AM
This work is led by my better half, the superstar @taylorszyszka.bsky.social and is our first paper together! Many thanks to our supervisor @yuhenglau.bsky.social for incredible support and of course, from contributors Alex, Lachlan, Regi, Titus and collaborators Andrew and Claire from UTS.
How did we do this? A clean system of fusing a steric block to encapsulin protein cage monomer – prevents assembly. Take this in vitro, add *any* cargo to the reaction and cleave off the block. And voila! Assembled in vitro cages that are surprisingly better in every way.
November 26, 2024 at 5:32 AM
How did we do this? A clean system of fusing a steric block to encapsulin protein cage monomer – prevents assembly. Take this in vitro, add *any* cargo to the reaction and cleave off the block. And voila! Assembled in vitro cages that are surprisingly better in every way.