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retroflexepeeist.bsky.social
Nicole
@retroflexepeeist.bsky.social
110 followers 280 following 130 posts
[Insert Walt Whitman quote]
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retroflexepeeist.bsky.social
*not that there is a responsibility here, just that it's helpful for peeps who pop in and out occasionally. (I don't want to contribute to someone's reach/influence if they're a bad egg, but I don't know what I don't know...you know?)
November 24, 2025 at 12:38 AM
retroflexepeeist.bsky.social
It is genuinely helpful for people who are on the edges of the community for people who are affected to name & explain why they're blocking someone*.
Totally understand not wanting to get into it publicly - even just saying 'DM me if you have Qs' would help.
November 24, 2025 at 12:36 AM
retroflexepeeist.bsky.social
No particular order:

@pipersifton.bsky.social
@thequillandwhisper.bsky.social
@andlikewaterlilies.bsky.social
@ravenellewroteit.bsky.social
@persimmons-lemons.bsky.social
@southernsoulwrites.bsky.social
@feral-libra.bsky.social

IDK everyone's handle on Bluesky yet; I'm sure there's more!
November 16, 2025 at 10:34 PM
retroflexepeeist.bsky.social
Whoa
a close up of a man 's face with blue eyes looking at the camera .
ALT: a close up of a man 's face with blue eyes looking at the camera .
media.tenor.com
November 6, 2025 at 1:34 AM
Reposted by Nicole
sailorrooscout.bsky.social
In short, acetaminophen exposure during pregnancy is not linked to the risk of developing autism, ADHD, or intellectual disability.

The study has been published in Journal of the American Medical Association (JAMA). YES, it is PEER-REVIEWED.
• jamanetwork.com/journals/jam...

🧪🧵⬇️
Key Points Question Does acetaminophen use during pregnancy increase children's risk of neurodevelopmental disorders? Findings In this population-based study, models without sibling controls identified marginally increased risks of autism and attention-deficit/hyperactivity disorder (ADHD) associated with acetaminophen use during pregnancy. However, analyses of matched full sibling pairs found no evidence of increased risk of autism (hazard ratio, 0.98), ADHD (hazard ratio, 0.98), or intellectual disability (hazard ratio, 1.01) associated with acetaminophen use. Meaning Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analyses. This suggests that associations observed in other models may have been attributable to confounding. Abstract Importance Several studies suggest that acetaminophen (paracetamol) use during pregnancy may increase risk of neurodevelopmental disorders in children. If true, this would have substantial implications for management of pain and fever during pregnancy. Objective To examine the associations of acetaminophen use during pregnancy with children's risk of autism, attention-deficit/hyperactivity disorder (ADHD), and intellectual disability. Design, Setting, and Participants This nationwide cohort study with sibling control analysis included a population-based sample of 2,480,797 children born in 1995 to 2019 in Sweden, with follow-up through December 31, 2021. Exposure Use of acetaminophen during pregnancy prospectively recorded from antenatal and prescription records. Main Outcomes and Measures Autism, ADHD, and intellectual disability based on International Classification of Diseases, Ninth Revision and International Classification of Diseases, Tenth Revision codes in health registers. Results In total, 185909 children (7.49%) were exposed to acetaminophen during pregnancy. Crude absolute risks at 10 years of age for those not exposed vs those exposed to acetaminophen were 1.33% vs 1.53% for autism, 2.46% vs 2.87% for ADHD, and 0.70% vs 0.82% for intellectual disability. In models without sibling control, ever-use vs no use of acetaminophen during pregnancy was associated with marginally increased risk of autism (hazard ratio [HR], 1.05 [95% CI, 1.02-1.08]; risk difference [RD] at 10 years of age, 0.09% [95% Cl, -0.01% to 0.20%l), ADHD (HR, 1.07 [95% Cl, 1.05-1.10]; RD, 0.21% [95% Cl, 0.08%-0.34%]), and intellectual disability (HR, 1.05 [95% CI, 1.00-1.10]; RD, 0.04% [95% Cl, -0.04% to 0.12%]). To address unobserved confounding, matched full sibling pairs were also analyzed. Sibling control analyses found no evidence that acetaminophen use during pregnancy was associated with autism (HR, 0.98 [95% Cl, 0.93-1.04]; RD, 0.02% [95% Cl, -0.14% to 0.18%l), ADHD (HR, 0.98 [95% Cl, 0.94-1.02]; RD, -0.02% [95% Cl, -0.21% to 0.15%]), or intellectual disability (HR, 1.01 195% Cl, 0.92-1.10]; RD, 0% [95% Cl, -0.10% to 0.13%1). Similarly, there was no evidence of a dose-response pattern in sibling control analyses. For example, for autism, compared with no use of acetaminophen, persons with low (<25th percentile), medium (25th-75th percentile), and high (>75th percentile) mean daily acetaminophen use had HRs of 0.85, 0.96, and 0.88, respectively. Conclusions and Relevance Acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis. This suggests that associations observed in other models may have been attributable to familial confounding. The study was supported by National Institutes of Health's National Institute of Neurological Disorders and Stroke 1R01NS107607.
October 30, 2025 at 4:02 PM
retroflexepeeist.bsky.social
Have fuuuuuun 💜😂
October 19, 2025 at 5:04 AM
retroflexepeeist.bsky.social
This is where I'm at mentally rn 😂
October 19, 2025 at 4:56 AM
Reposted by Nicole
anildash.com
"I have a decent fluency in LLMs, and they have utility, but the absurd degree of over-hype, the way they're being forced on everyone, and the insistence on ignoring the many valid critiques about them make it very difficult to focus on legitimate uses where they might add value."
October 17, 2025 at 4:32 AM
retroflexepeeist.bsky.social
I love that I was born with the 'how hard can it be' gene 😅
October 1, 2025 at 7:38 PM