Ren Vien Anthony Fernandez
renvien97.bsky.social
Ren Vien Anthony Fernandez
@renvien97.bsky.social
PhD Student Laboratory of Advanced Chemical Biology Hokkaido University Japan focusing on Glycobiology #GlycopeptideSynthesis
Reposted by Ren Vien Anthony Fernandez
Did you know the extracellular matrix has a sweet side? New research from the Robert Haltiwanger at @universityofga.bsky.social is shaking up what we know about Marfan syndrome! #glycotime #biochemistry #humanhealth

- Journal of Biological Chemistry www.jbc.org/article/S002...
Marfan syndrome variation of the POGLUT2 and POGLUT3 consensus sequence can produce aberrant fibrillin-1 O-glucosylation
Fibrillin-1 (FBN1) is an essential component of the extracellular matrix, forming microfibril bundles that are important for the proper development of elastic tissues found in the aorta and lung, as w...
www.jbc.org
September 29, 2025 at 3:10 PM
Reposted by Ren Vien Anthony Fernandez
Our work @benschulz.bsky.social on the specificity and the mechanism of activation of the eukaryotic oligosaccharyltransferase is now on Glycopedia ⬇️🎉🥳, the largest repository of #glycotime news and educational material online!

Thank you Serge Perez 🤓❤️

glycopedia.eu/2025/09/09/r...
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase - Glycopedia
Oligosaccharyltransferase (OST) catalyses the key step of N-glycosylation, transferring immature N-glycans to select Asn residues in nascent proteins in the endoplasmic reticulum (ER). Asn are more li...
glycopedia.eu
September 16, 2025 at 7:16 PM
Reposted by Ren Vien Anthony Fernandez
Breaking news: Richard Cummings created a Periodic Table of Monosaccharides! So next time someone says “sugar is simple,” just casually drop that there’s a whole periodic table for them! #glycotime 🧪
academic.oup.com/glycob/artic...
Validate User
academic.oup.com
September 19, 2025 at 2:42 PM
Reposted by Ren Vien Anthony Fernandez
Organocatalyzed Synthesis of 2-Deoxyglycosyl Azides: Application in 1,2,3-Triazole Linked 2-Deoxyglycosides.
#glycotime #CarbohydrateResearch
Organocatalyzed Synthesis of 2-Deoxyglycosyl Azides: Application in 1,2,3-Triazole Linked 2-Deoxyglycosides.
Organocatalyzed Synthesis of 2-Deoxyglycosyl Azides: Application in 1,2,3-Triazole Linked 2-Deoxyglycosides.
www.sciencedirect.com
September 14, 2025 at 2:50 PM
Reposted by Ren Vien Anthony Fernandez
Smart-responsive Dual Cross-linked Chitooligosaccharide Nanoparticles with High Stability and ROS-triggered Self-accelerating Drug Release for Enhanced Breast Cancer Therapy
#glycotime #CarbohydrateResearch
Smart-responsive Dual Cross-linked Chitooligosaccharide Nanoparticles with High Stability and ROS-triggered Self-accelerating Drug Release for Enhanced Breast Cancer Therapy
Smart-responsive Dual Cross-linked Chitooligosaccharide Nanoparticles with High Stability and ROS-triggered Self-accelerating Drug Release for Enhanced Breast Cancer Therapy
www.sciencedirect.com
September 15, 2025 at 2:50 PM
Reposted by Ren Vien Anthony Fernandez
Synthesis and characterization of selenourea-functionalized chitosan derivatives with enhanced antioxidant activity
#glycotime #CarbohydrateResearch
Synthesis and characterization of selenourea-functionalized chitosan derivatives with enhanced antioxidant activity
S000862152500268X
www.sciencedirect.com
August 12, 2025 at 2:50 PM
Reposted by Ren Vien Anthony Fernandez
Glycoengineering of nematode antigens using insect cells: a promising approach for producing bioactive vaccine antigens of the barber’s pole worm Haemonchus contortu#glycotimem#Glycobiologygy
Glycoengineering of nematode antigens using insect cells: a promising approach for producing bioactive vaccine antigens of the barber’s pole worm Haemonchus contortus
Abstract. The H11 antigens, located on the intestinal microvilli of Haemonchus contortus, comprise a group of homologous aminopeptidases essential for the
academic.oup.com
August 10, 2025 at 2:39 PM
Reposted by Ren Vien Anthony Fernandez
Systematic and comprehensive analysis of major localizations of alpha-dystroglycan-specific modifying enzymes
#glycotime #Glycobiology
Systematic and comprehensive analysis of major localizations of alpha-dystroglycan-specific modifying enzymes
Abstract. DG binds to extracellular matrix via its O-glycans, which are sequentially modified in a specific order by DG-specific enzymes: POMGNT2, B3GalNT2
academic.oup.com
May 11, 2025 at 2:39 PM
Reposted by Ren Vien Anthony Fernandez
Glycosylation of Structured Protein Domains in Cell-Free Reaction Environments | ACS Synthetic Biology pubs.acs.org/doi/10.1021/...
Glycosylation of Structured Protein Domains in Cell-Free Reaction Environments
The production of N-linked glycoproteins in genetically tractable bacterial hosts and their cell-free extracts holds great promise for low-cost, customizable, and distributed biomanufacturing of glyco...
pubs.acs.org
May 31, 2025 at 6:31 PM
Reposted by Ren Vien Anthony Fernandez
Recently came across this during lit review. A solid mechanistic study with a big performance improvement as a result.
www.sciencedirect.com/science/arti...
Addressing NHS chemistry: Efficient quenching of excess TMT reagent and reversing TMT-over labelling in proteomic samples by methylamine
N-Hydroxysuccinimide (NHS) ester chemistry is used extensively across proteomics sample preparation. One of its increasingly prevalent applications is…
www.sciencedirect.com
March 28, 2025 at 10:36 AM