Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
@raja-sekhar.bsky.social
Software | FinTech | PropTech | HealthcareTech | LifesciencesTech | SocialTech | Waste Management | Entrepreneurship
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
"Why does the brain need billions of neurons to process 10 bits/second? Why can we only think about one thing at a time?"
www.cell.com/neuron/fullt...
From The Unbearable Slowness of Being
www.cell.com/neuron/fullt...
From The Unbearable Slowness of Being
December 17, 2024 at 4:09 PM
"Why does the brain need billions of neurons to process 10 bits/second? Why can we only think about one thing at a time?"
www.cell.com/neuron/fullt...
From The Unbearable Slowness of Being
www.cell.com/neuron/fullt...
From The Unbearable Slowness of Being
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Did you know ?
Genomic testing in a large cohort of patients with Cerebral Palsy indicate that actionable genetic findings occurred in 8% of individuals and pathogenic variants in 27%. jamanetwork.com/journals/jam...
Genomic testing in a large cohort of patients with Cerebral Palsy indicate that actionable genetic findings occurred in 8% of individuals and pathogenic variants in 27%. jamanetwork.com/journals/jam...
December 5, 2024 at 6:14 PM
Did you know ?
Genomic testing in a large cohort of patients with Cerebral Palsy indicate that actionable genetic findings occurred in 8% of individuals and pathogenic variants in 27%. jamanetwork.com/journals/jam...
Genomic testing in a large cohort of patients with Cerebral Palsy indicate that actionable genetic findings occurred in 8% of individuals and pathogenic variants in 27%. jamanetwork.com/journals/jam...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
🤔 Why do we extract diffusion features from noisy images? Isn’t that destroying information?
Yes, it is - but we found a way to do better. 🚀
Here’s how we unlock better features, no noise, no hassle.
📝 Project Page: compvis.github.io/cleandift
💻 Code: github.com/CompVis/clea...
🧵👇
Yes, it is - but we found a way to do better. 🚀
Here’s how we unlock better features, no noise, no hassle.
📝 Project Page: compvis.github.io/cleandift
💻 Code: github.com/CompVis/clea...
🧵👇
December 4, 2024 at 11:31 PM
🤔 Why do we extract diffusion features from noisy images? Isn’t that destroying information?
Yes, it is - but we found a way to do better. 🚀
Here’s how we unlock better features, no noise, no hassle.
📝 Project Page: compvis.github.io/cleandift
💻 Code: github.com/CompVis/clea...
🧵👇
Yes, it is - but we found a way to do better. 🚀
Here’s how we unlock better features, no noise, no hassle.
📝 Project Page: compvis.github.io/cleandift
💻 Code: github.com/CompVis/clea...
🧵👇
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Introducing a new approach to graph-enabled RAG. LazyGraphRAG needs no prior summarization of source data, avoiding prohibitive up-front indexing costs. It’s inherently scalable in cost and quality across multiple methods and search mechanisms: www.microsoft.com/en-us/resear...
November 25, 2024 at 5:17 PM
Introducing a new approach to graph-enabled RAG. LazyGraphRAG needs no prior summarization of source data, avoiding prohibitive up-front indexing costs. It’s inherently scalable in cost and quality across multiple methods and search mechanisms: www.microsoft.com/en-us/resear...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Where did our neck muscles come from?🧪
Here's our #evodevo #devbio deep dive feat. #zebrafish, mouse, axolotls, & more!
Led by Eglantine Heude & Tajbakhsh lab at Pasteur, the team at National Museum of Natural History France, & lab alumni Karin Prummel & Rob Lalonde.
www.nature.com/articles/s41...
Here's our #evodevo #devbio deep dive feat. #zebrafish, mouse, axolotls, & more!
Led by Eglantine Heude & Tajbakhsh lab at Pasteur, the team at National Museum of Natural History France, & lab alumni Karin Prummel & Rob Lalonde.
www.nature.com/articles/s41...
Co-option of neck muscles supported the vertebrate water-to-land transition - Nature Communications
The evolutionary water-to-land transition involved the separation of the skull from the pectoral girdle, though these musculoskeletal changes have not been deeply characterised. Here they show that th...
www.nature.com
December 5, 2024 at 12:02 AM
Where did our neck muscles come from?🧪
Here's our #evodevo #devbio deep dive feat. #zebrafish, mouse, axolotls, & more!
Led by Eglantine Heude & Tajbakhsh lab at Pasteur, the team at National Museum of Natural History France, & lab alumni Karin Prummel & Rob Lalonde.
www.nature.com/articles/s41...
Here's our #evodevo #devbio deep dive feat. #zebrafish, mouse, axolotls, & more!
Led by Eglantine Heude & Tajbakhsh lab at Pasteur, the team at National Museum of Natural History France, & lab alumni Karin Prummel & Rob Lalonde.
www.nature.com/articles/s41...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Did we conceive the structure of neurons incorrectly all these years?
nature.com/articles/s41...
not smooth, cylindrical strands but a string of pearls?
it's controversial
science.org/content/arti...
@science.org
nature.com/articles/s41...
not smooth, cylindrical strands but a string of pearls?
it's controversial
science.org/content/arti...
@science.org
Membrane mechanics dictate axonal pearls-on-a-string morphology and function - Nature Neuroscience
Axons have always been assumed to be cylindrical. Using in silico modeling and cryopreservation of tissues, Griswold et al. demonstrate that unmyelinated axons of the mammalian central nervous system ...
nature.com
December 2, 2024 at 10:13 PM
Did we conceive the structure of neurons incorrectly all these years?
nature.com/articles/s41...
not smooth, cylindrical strands but a string of pearls?
it's controversial
science.org/content/arti...
@science.org
nature.com/articles/s41...
not smooth, cylindrical strands but a string of pearls?
it's controversial
science.org/content/arti...
@science.org
If there is one thing you can read this weekend, let it be this.
#integrity
.everyone is a hero in their own mind
www.linkedin.com/pulse/everyo...
#integrity
.everyone is a hero in their own mind
www.linkedin.com/pulse/everyo...
.everyone is a hero in their own mind
I used to dream about landing on Forbes 30 Under 30. The validation, the recognition, the proof that I "made it.
www.linkedin.com
November 30, 2024 at 1:48 PM
If there is one thing you can read this weekend, let it be this.
#integrity
.everyone is a hero in their own mind
www.linkedin.com/pulse/everyo...
#integrity
.everyone is a hero in their own mind
www.linkedin.com/pulse/everyo...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
It’s a big day for @genesandhealth.bsky.social @samcbhodgson.bsky.social @moneeza-ks.bsky.social Genes & Health, with @ Sam Hodgson, Moneeza Kalhan Siddiqui and I, as we publish our paper rdcu.be/d1vj0 on the genetic basis of #type2diabetes & #gestationaldiabetes (#T2D and #GDM) in south Asians. A🧵
Genetic basis of early onset and progression of type 2 diabetes in South Asians
Nature Medicine - In a cohort of 50,556 South Asian individuals, partitioned polygenic scores helped identify genetic susceptibility to insulin deficiency and unfavorable fat distribution as key...
rdcu.be
November 26, 2024 at 5:52 PM
It’s a big day for @genesandhealth.bsky.social @samcbhodgson.bsky.social @moneeza-ks.bsky.social Genes & Health, with @ Sam Hodgson, Moneeza Kalhan Siddiqui and I, as we publish our paper rdcu.be/d1vj0 on the genetic basis of #type2diabetes & #gestationaldiabetes (#T2D and #GDM) in south Asians. A🧵
Google launches Health AI Developer Foundations (HAI-DEF), a public resource to help developers build & implement AI models for healthcare - includes foundation models for chest xray, pathology and skin images.
research.google/blog/helping...
research.google/blog/helping...
Helping everyone build AI for healthcare applications with open foundation models
research.google
November 26, 2024 at 2:37 PM
Google launches Health AI Developer Foundations (HAI-DEF), a public resource to help developers build & implement AI models for healthcare - includes foundation models for chest xray, pathology and skin images.
research.google/blog/helping...
research.google/blog/helping...
Am putting together a starter pack for openEHR and FHIR handles to follow. Please recommend.
go.bsky.app/1nGqY8
go.bsky.app/1nGqY8
November 24, 2024 at 10:21 PM
Am putting together a starter pack for openEHR and FHIR handles to follow. Please recommend.
go.bsky.app/1nGqY8
go.bsky.app/1nGqY8
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Don't miss the next #Knowmics webinar on #Pharmacogenomics of antidiabetic drugs in India
Register at forms.gle/M8pJChBmDFS2...
Register at forms.gle/M8pJChBmDFS2...
November 21, 2024 at 5:59 PM
Don't miss the next #Knowmics webinar on #Pharmacogenomics of antidiabetic drugs in India
Register at forms.gle/M8pJChBmDFS2...
Register at forms.gle/M8pJChBmDFS2...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
A new foundation model for nearly all (9!) medical imaging modalities, BiomedParse
www.nature.com/articles/s41...
explainer: www.microsoft.com/en-us/resear...
www.nature.com/articles/s41...
explainer: www.microsoft.com/en-us/resear...
November 18, 2024 at 1:15 PM
A new foundation model for nearly all (9!) medical imaging modalities, BiomedParse
www.nature.com/articles/s41...
explainer: www.microsoft.com/en-us/resear...
www.nature.com/articles/s41...
explainer: www.microsoft.com/en-us/resear...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Don't miss the upcoming #Knowmics Webinar on Clincial Genomic Testing at MSKCC by Dr.Michael Berger on 20th November 2024 20.00 hts IST
Register
docs.google.com/forms/d/e/1F...
Register
docs.google.com/forms/d/e/1F...
November 17, 2024 at 5:49 PM
Don't miss the upcoming #Knowmics Webinar on Clincial Genomic Testing at MSKCC by Dr.Michael Berger on 20th November 2024 20.00 hts IST
Register
docs.google.com/forms/d/e/1F...
Register
docs.google.com/forms/d/e/1F...
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
November 16, 2024 at 3:19 PM
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
One of the exciting things happening in AI for Science has been the growth in lab automation.
Automated labs coupled with active learning are a super exciting area with lots of opportunities for progress.
I promised @cpaxton.bsky.social a short thread on this, so here it goes!
🧪
Automated labs coupled with active learning are a super exciting area with lots of opportunities for progress.
I promised @cpaxton.bsky.social a short thread on this, so here it goes!
🧪
November 16, 2024 at 9:10 PM
One of the exciting things happening in AI for Science has been the growth in lab automation.
Automated labs coupled with active learning are a super exciting area with lots of opportunities for progress.
I promised @cpaxton.bsky.social a short thread on this, so here it goes!
🧪
Automated labs coupled with active learning are a super exciting area with lots of opportunities for progress.
I promised @cpaxton.bsky.social a short thread on this, so here it goes!
🧪
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Harmonized data for clinical interpretation of genetic variants are key to uniform approaches to informed decision making and genetic counseling in clinical settings. #BRCAIndica is a step in this direction rdcu.be/d0o58
November 16, 2024 at 3:58 PM
Harmonized data for clinical interpretation of genetic variants are key to uniform approaches to informed decision making and genetic counseling in clinical settings. #BRCAIndica is a step in this direction rdcu.be/d0o58
Reposted by Raja Sekhar Kommu (రాజ శేఖర్ కొమ్ము)
Wait till the Department of Government Efficiency gets into the AWS billing console
November 15, 2024 at 2:09 PM
Wait till the Department of Government Efficiency gets into the AWS billing console