John Purdy
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purdylab.bsky.social
John Purdy
@purdylab.bsky.social
Viruses, metabolism, lipids, mass spec, herpes (both 🦠 and 🦎, but not reptile viruses).
Reposted by John Purdy
Interested in shaping ASV decisions? Do you know someone who is? Nominations for ASV President-Elect and a number of Virology Councilors are due on November 21. Look for the nomination form in your ASV member email!
November 13, 2025 at 6:15 PM
Reposted by John Purdy
This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi
Medicine Nobel goes to three researchers who identified immune system’s security guards
Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease
scim.ag
October 6, 2025 at 1:45 PM
Reposted by John Purdy
New CNN story about clinical trials damaged by the funding freeze at Northwestern.

www.cnn.com/2025/06/23/h...

1/n
NIH froze funding for clinical trials at a major university. By fall, they’ll run out of funding | CNN
Northwestern University hasn’t received any funding from the NIH since the end of March. Not only could patients potentially stop receiving treatments that trials provided, the research itself could b...
www.cnn.com
June 23, 2025 at 12:16 PM
Reposted by John Purdy
2 in a row in the Journal of Virology.

A new paper from our group & the new Johnson lab at UTMB.

Here, we find multiple variant mutations in the SR rich domain of N facilitate improved infection with #SARS2.

A brief thread since this didn't get preprinted

journals.asm.org/doi/10.1128/...
Convergent evolution in nucleocapsid facilitated SARS-CoV-2 adaptation for human infection | Journal of Virology
After its emergence, SARS-CoV-2 rapidly adapted to human infection, acquiring numerous mutations across its genome. Many of these mutations remain uncharacterized. This study examines a mutational hot...
journals.asm.org
June 13, 2025 at 2:18 PM
Reposted by John Purdy
"If NIH and HHS leadership comply with these orders, as a cisgender bisexual man I am forced to ask myself what support, if any, I should expect to receive when this administration decides to unfairly and irrationally target other populations within the LGBTQ..."

- Me January 29 to Acting NIH Dir.
February 25, 2025 at 1:17 AM
Reposted by John Purdy
Vaccines work! As measles cases have recently been reported in Alaska, Georgia, New York, Rhode Island and Texas, it's important to remember that prior to the introduction of the measles vaccine in 1963, measles killed 400-500 people and resulted in ~48,000 hospitalizations per year.
February 13, 2025 at 3:10 PM
Congratulations to @rmokry.bsky.social on her first pub from the lab.

www.pnas.org/doi/10.1073/...
February 10, 2025 at 11:53 PM