Mahmoud Pouladi
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pouladilab.bsky.social
Mahmoud Pouladi
@pouladilab.bsky.social
Associate Professor, BCCHRI, University of British Columbia :: Neurogenetics :: NDDs :: Disease Modelling :: Drug Discovery :: iPSCs
This special issue brings together expert reviews that explore these important emerging areas of research.

A big thank you to all the contributing authors for their excellent work synthesizing these emerging insights, and to the reviewers for their constructive feedback.

3/3
August 8, 2025 at 12:54 AM
For decades, Huntington's disease research has focused primarily on neuronal vulnerability. However, mounting evidence reveals that astrocytes, microglia, oligodendrocytes, and other non-neuronal cells play crucial roles as active participants in HD pathogenesis.

2/3
August 8, 2025 at 12:54 AM
This study adds a new dimension to our understanding of how aging alters oligodendrocytes and myelin plasticity, and their link to cognitive resilience. A fascinating read!
March 7, 2025 at 5:22 AM
Why does Plp1 matter? Myelination is crucial for brain function, and its dysregulation is linked to cognitive decline. With age, Plp1 expression rises in the female hippocampus. The authors show that boosting Plp1 in older mice (both male & female) led to improved memory performance.
March 7, 2025 at 5:22 AM
Reposted by Mahmoud Pouladi
My group would take at least 2 people interested in neurodegeneration as post docs bsky.app/profile/maxi...
We are looking for motivated post docs. Projects on Alzheimer’s and Synucleinopathy. New mouse models, combined lightsheet/15.2T MRI and high throughput cognitive testing using touchscreens. Perfect for a recent graduate in Neurosciences or related field. Come work with us in 🇨🇦 👊😀🧪 please share.
February 15, 2025 at 3:35 PM
Added to the HD starter pack! :)
February 7, 2025 at 4:12 AM