Páll Melsted
@pmelsted.bsky.social
Professor @hi.is in CS, head of rna seq data analysis at decode genetics (views are mine). Bioinformatician, epistemic trespasser, &c.
ps. I hate GTF files
ps. I hate GTF files
Today I found out that the Pacbio tools for working with barcodes and adapters in Kinnex are called lima and skera. To whomever came up with that joke, I salute you, you’ve reached 50% of the audience
October 31, 2025 at 2:06 PM
Today I found out that the Pacbio tools for working with barcodes and adapters in Kinnex are called lima and skera. To whomever came up with that joke, I salute you, you’ve reached 50% of the audience
All right, I posed this question to my PhD student this morning and he looked at me funny and asked if it was a trick question
What is the running time of this code
a, b = 0, 1
for _ in range(2, n+1):
a, b = b, a + b
return b
What is the running time of this code
a, b = 0, 1
for _ in range(2, n+1):
a, b = b, a + b
return b
October 7, 2025 at 10:12 PM
All right, I posed this question to my PhD student this morning and he looked at me funny and asked if it was a trick question
What is the running time of this code
a, b = 0, 1
for _ in range(2, n+1):
a, b = b, a + b
return b
What is the running time of this code
a, b = 0, 1
for _ in range(2, n+1):
a, b = b, a + b
return b
Happy Q4 for those who celebrate
October 1, 2025 at 8:31 PM
Happy Q4 for those who celebrate
Today I fixed a humming converter and an intercom receiver set from the 70’s. I’m surprised at how good ChatGPT is at diagnosing problems and coming up with fixes for hardware that is older than me. Since I didn’t have to replace the units I can justify the cost and environmental impact of AI
September 27, 2025 at 11:28 PM
Today I fixed a humming converter and an intercom receiver set from the 70’s. I’m surprised at how good ChatGPT is at diagnosing problems and coming up with fixes for hardware that is older than me. Since I didn’t have to replace the units I can justify the cost and environmental impact of AI
Reposted by Páll Melsted
The Genome Informatics conference (@ Cold Spring Harbor Lab, Nov 5 - 8) abstract deadline is **today**. We welcome your submissions! Topics include:
- PanGenomes
- Genome Assembly & Seq. Algos.
- Algorithmic Evo. Bio
- Single Cell & Spatial Omics
- Microbial Genomics
- AI/ML & Integrative Omics
🙏🙏🙏
- PanGenomes
- Genome Assembly & Seq. Algos.
- Algorithmic Evo. Bio
- Single Cell & Spatial Omics
- Microbial Genomics
- AI/ML & Integrative Omics
🙏🙏🙏
August 22, 2025 at 3:00 PM
The Genome Informatics conference (@ Cold Spring Harbor Lab, Nov 5 - 8) abstract deadline is **today**. We welcome your submissions! Topics include:
- PanGenomes
- Genome Assembly & Seq. Algos.
- Algorithmic Evo. Bio
- Single Cell & Spatial Omics
- Microbial Genomics
- AI/ML & Integrative Omics
🙏🙏🙏
- PanGenomes
- Genome Assembly & Seq. Algos.
- Algorithmic Evo. Bio
- Single Cell & Spatial Omics
- Microbial Genomics
- AI/ML & Integrative Omics
🙏🙏🙏
Perfect marketing doesn’t exi…
July 5, 2025 at 11:22 AM
Perfect marketing doesn’t exi…
It is by the juice of coffee that thoughts acquire speed …
June 27, 2025 at 12:39 PM
It is by the juice of coffee that thoughts acquire speed …
Reposted by Páll Melsted
Job alert: Join us for a postdoc in AI in genetics at @EMBL Heidelberg! Great collaboration with @Adrian Cortes @GSK, aiming to develop new tools to elucidate genetic effects using population-scale cohorts and single-cell readouts. Please share!
embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...
embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...
Postdoctoral Researcher in Computational Genetics
The research group of Oliver Stegle looks for a postdoctoral researcher to join a collaborative project with GSK with the goal to apply computational methods to investigate the effects of rare variant...
embl.wd103.myworkdayjobs.com
June 26, 2025 at 10:00 AM
Job alert: Join us for a postdoc in AI in genetics at @EMBL Heidelberg! Great collaboration with @Adrian Cortes @GSK, aiming to develop new tools to elucidate genetic effects using population-scale cohorts and single-cell readouts. Please share!
embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...
embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...
I misread that as “message” which would have been more impressive 🚩
June 24, 2025 at 12:57 PM
I misread that as “message” which would have been more impressive 🚩
Reposted by Páll Melsted
Reposted by Páll Melsted
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
June 1, 2025 at 3:33 PM
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
In Iceland spring is not something you define as season based on weather but more from the arrival of migratory birds
May 9, 2025 at 9:01 AM
In Iceland spring is not something you define as season based on weather but more from the arrival of migratory birds
My favorite brainrot is an account on TikTok that solves complicated integrals on a blackboard with colored chalk.
May 5, 2025 at 9:39 AM
My favorite brainrot is an account on TikTok that solves complicated integrals on a blackboard with colored chalk.
There is something refreshingly honest about moving the goalpost this blatantly. Adjusting for multiple testing? Not in my house ☝️
April 30, 2025 at 10:20 PM
There is something refreshingly honest about moving the goalpost this blatantly. Adjusting for multiple testing? Not in my house ☝️
Reposted by Páll Melsted
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
April 22, 2025 at 5:24 PM
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Today I gave a lecture in a brand new lecture hall where the projector was acting weird. Turned out that the control panel showed green for when the projector was off, you had to press the button wait 10 seconds and then it turned red.
I think this should be a case study in UI design
I think this should be a case study in UI design
March 4, 2025 at 9:10 PM
Today I gave a lecture in a brand new lecture hall where the projector was acting weird. Turned out that the control panel showed green for when the projector was off, you had to press the button wait 10 seconds and then it turned red.
I think this should be a case study in UI design
I think this should be a case study in UI design
I might need to replicate this paper www.nature.com/articles/s44...
Periodic cooking of eggs - Communications Engineering
Emilia Di Lorenzo and colleagues propose an approach to address the energy transport problem of cooking the albumen and yolk of a boiled egg at their optimal temperatures without separation. By altern...
www.nature.com
February 7, 2025 at 1:20 PM
I might need to replicate this paper www.nature.com/articles/s44...
Somehow I would be more confident that the Tesla could drive autonomously if the auto mode on the windshield wipers worked.
January 23, 2025 at 9:52 PM
Somehow I would be more confident that the Tesla could drive autonomously if the auto mode on the windshield wipers worked.
Ironically this is the best content on that other place
January 13, 2025 at 2:19 PM
Ironically this is the best content on that other place
Beautiful polar stratospheric clouds today
January 5, 2025 at 5:25 PM
Beautiful polar stratospheric clouds today
Productivity tip: set your phone to do not disturb, close all messaging software and email apps on your laptop, put on your headphones and Koyaanisqatsi on repeat. Don’t forget coffee.
December 5, 2024 at 12:29 AM
Productivity tip: set your phone to do not disturb, close all messaging software and email apps on your laptop, put on your headphones and Koyaanisqatsi on repeat. Don’t forget coffee.
Let’s see if this bsky thing works. I have a 4K monitor at home and I want to connect a Mac mini and a Mac laptop to the monitor and external keyboard/mouse. Any recommendations on a KVM setup or favorite keyboard & mouse?
November 22, 2024 at 2:30 AM
Let’s see if this bsky thing works. I have a 4K monitor at home and I want to connect a Mac mini and a Mac laptop to the monitor and external keyboard/mouse. Any recommendations on a KVM setup or favorite keyboard & mouse?
Heading out to #genomeinformatics2024 remember to bring your adapters
November 12, 2024 at 7:38 PM
Heading out to #genomeinformatics2024 remember to bring your adapters
Today I almost obsessed over a piece of code that turns out took 7.6 seconds to run. Writing the code to measure the time took half a second, I just wrote a comment and cursor filled in the rest and I hit tab. Prior to AI I would have spent half an hour reading docs or stack overflow
November 5, 2024 at 2:53 AM
Today I almost obsessed over a piece of code that turns out took 7.6 seconds to run. Writing the code to measure the time took half a second, I just wrote a comment and cursor filled in the rest and I hit tab. Prior to AI I would have spent half an hour reading docs or stack overflow
Reposted by Páll Melsted
Reposting! This faculty search is open through December
NHGRI is searching for new faculty in computational genomics! The NIH intramural program funds labs, not projects, so it's all research and no grant writing. Come work with me at one of the best places in the world to do genomics research! #ASHG23 www.genome.gov/careers-trai...
CGDSR Tenure-Track or Tenure-Eligible Investigator Recruitment
NHGRI seeks to identify outstanding tenure-track or tenure-eligible investigators for the newly established Center for Genomics and Data Science Research (CGDSR) within the Division of Intramural Rese...
www.genome.gov
November 28, 2023 at 4:56 PM
Reposting! This faculty search is open through December