Christina Megli
@placentamdphd.bsky.social
Mfm, MD/PhD, physician scientist studying placental immune defenses, dog mom,
Reposted by Christina Megli
Today, USAID shuts down.
Experts say this could lead to 14 million deaths by 2030—including 4.5 million babies and children under 5.
Let’s not forget, Trump recently let a warehouse full of food aid rot rather than feed the hungry.
This isn’t America first. It’s America heartless.
Experts say this could lead to 14 million deaths by 2030—including 4.5 million babies and children under 5.
Let’s not forget, Trump recently let a warehouse full of food aid rot rather than feed the hungry.
This isn’t America first. It’s America heartless.
July 1, 2025 at 1:28 PM
Today, USAID shuts down.
Experts say this could lead to 14 million deaths by 2030—including 4.5 million babies and children under 5.
Let’s not forget, Trump recently let a warehouse full of food aid rot rather than feed the hungry.
This isn’t America first. It’s America heartless.
Experts say this could lead to 14 million deaths by 2030—including 4.5 million babies and children under 5.
Let’s not forget, Trump recently let a warehouse full of food aid rot rather than feed the hungry.
This isn’t America first. It’s America heartless.
Reposted by Christina Megli
Dave McCormick just cast the deciding vote for this BS bill that raises costs of health care, food and utilities, and leaves Pennsylvanians to die.
The bill now goes to the House where PA’s GOP delegation will decide its fate. Call and let them know how you feel at 202-224-3121.
The bill now goes to the House where PA’s GOP delegation will decide its fate. Call and let them know how you feel at 202-224-3121.
July 1, 2025 at 5:29 PM
Dave McCormick just cast the deciding vote for this BS bill that raises costs of health care, food and utilities, and leaves Pennsylvanians to die.
The bill now goes to the House where PA’s GOP delegation will decide its fate. Call and let them know how you feel at 202-224-3121.
The bill now goes to the House where PA’s GOP delegation will decide its fate. Call and let them know how you feel at 202-224-3121.
Reposted by Christina Megli
This is devastating for women’s health research globally, given the influential work by WHI
🔪 Another attack on women
🚫 Fewer discoveries to understand female biology, health & disease
🚫 Fewer diagnostics, therapeutics, preventions
💀More disease, suffering, death
www.science.org/content/arti...
🔪 Another attack on women
🚫 Fewer discoveries to understand female biology, health & disease
🚫 Fewer diagnostics, therapeutics, preventions
💀More disease, suffering, death
www.science.org/content/arti...
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
www.science.org
April 23, 2025 at 7:51 AM
This is devastating for women’s health research globally, given the influential work by WHI
🔪 Another attack on women
🚫 Fewer discoveries to understand female biology, health & disease
🚫 Fewer diagnostics, therapeutics, preventions
💀More disease, suffering, death
www.science.org/content/arti...
🔪 Another attack on women
🚫 Fewer discoveries to understand female biology, health & disease
🚫 Fewer diagnostics, therapeutics, preventions
💀More disease, suffering, death
www.science.org/content/arti...
Reposted by Christina Megli
NT-proBNP as a biomarker to predict pre-eclampsia and maternal-fetal complications
N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications
obgyn.onlinelibrary.wiley.com
April 19, 2025 at 8:44 PM
NT-proBNP as a biomarker to predict pre-eclampsia and maternal-fetal complications
Reposted by Christina Megli
📢 Call for abstracts!
⏰ Deadline 12 May
We're looking for poster and flash talk presenters for this July's Annual Meeting, themed 'The Placenta at Term'
www.trophoblast.cam.ac.uk/ctrconferenc...
⏰ Deadline 12 May
We're looking for poster and flash talk presenters for this July's Annual Meeting, themed 'The Placenta at Term'
www.trophoblast.cam.ac.uk/ctrconferenc...
Poster and flash talk presenter corner | Loke Centre for Trophoblast Research
Abstract submission - for 2025 We invite abstract submissions to be considered for 3-minute flash talks and poster presentations for the 2025 Annual Meeting on topics relating to The Placenta at Term....
www.trophoblast.cam.ac.uk
April 16, 2025 at 1:26 PM
📢 Call for abstracts!
⏰ Deadline 12 May
We're looking for poster and flash talk presenters for this July's Annual Meeting, themed 'The Placenta at Term'
www.trophoblast.cam.ac.uk/ctrconferenc...
⏰ Deadline 12 May
We're looking for poster and flash talk presenters for this July's Annual Meeting, themed 'The Placenta at Term'
www.trophoblast.cam.ac.uk/ctrconferenc...
pubmed.ncbi.nlm.nih.gov/40221000/ 👇👇👇👇amazing development for placental research!
Derivation of human trophoblast stem cells from placentas at birth - PubMed
Human trophoblast stem cells (hTSCs) have emerged as a powerful tool for modeling the placental cytotrophoblast (CTB) in vitro. hTSCs were originally derived from CTBs of the first trimester placenta ...
pubmed.ncbi.nlm.nih.gov
April 16, 2025 at 2:02 PM
pubmed.ncbi.nlm.nih.gov/40221000/ 👇👇👇👇amazing development for placental research!
Reposted by Christina Megli
Birth defects often occur randomly
Abortion for birth defects is illegal in many states
Now government support for birth defects is severely curtailed
So a healthy person could have a birth defect, be forced to carry to term, then left to the wolves.
#MedSky
www.medpagetoday.com/special-repo...
Abortion for birth defects is illegal in many states
Now government support for birth defects is severely curtailed
So a healthy person could have a birth defect, be forced to carry to term, then left to the wolves.
#MedSky
www.medpagetoday.com/special-repo...
Nearly Half of CDC Birth Defects and Disabilities Staff Cut
Programs in blood disorders, Special Olympics affected
www.medpagetoday.com
April 13, 2025 at 12:56 PM
Birth defects often occur randomly
Abortion for birth defects is illegal in many states
Now government support for birth defects is severely curtailed
So a healthy person could have a birth defect, be forced to carry to term, then left to the wolves.
#MedSky
www.medpagetoday.com/special-repo...
Abortion for birth defects is illegal in many states
Now government support for birth defects is severely curtailed
So a healthy person could have a birth defect, be forced to carry to term, then left to the wolves.
#MedSky
www.medpagetoday.com/special-repo...
Reposted by Christina Megli
Reposted by Christina Megli
Reposted by Christina Megli
The proposed dashboard means you can be identified without it disclosing your name, since enough patient descriptors will often allow you to find specific people
It’s a privacy violation wolf in public health sheep clothing
#MedSky
www.statenews.org/government-p...
It’s a privacy violation wolf in public health sheep clothing
#MedSky
www.statenews.org/government-p...
Ohio House budget changes abortion reporting requirements to get more patient information
The requirements call for a dashboard that will give immediate information about abortions being performed in Ohio.
www.statenews.org
April 15, 2025 at 10:16 AM
The proposed dashboard means you can be identified without it disclosing your name, since enough patient descriptors will often allow you to find specific people
It’s a privacy violation wolf in public health sheep clothing
#MedSky
www.statenews.org/government-p...
It’s a privacy violation wolf in public health sheep clothing
#MedSky
www.statenews.org/government-p...
Reposted by Christina Megli
Reposted by Christina Megli
April 7, 2025 at 4:10 AM
Reposted by Christina Megli
‘Injecting yourself daily is difficult to navigate at work’: Managing fertility treatment while working
www.irishtimes.com/health/2025/...
#Infertility #PregnancyLoss #Workplace
Ping #PLRG_PLACESproject
www.irishtimes.com/health/2025/...
#Infertility #PregnancyLoss #Workplace
Ping #PLRG_PLACESproject
‘Injecting yourself daily is difficult to navigate at work’: Managing fertility treatment while working
Meath woman Lisa McGee says being open with managers about her experience alleviated stress
www.irishtimes.com
April 7, 2025 at 4:49 AM
‘Injecting yourself daily is difficult to navigate at work’: Managing fertility treatment while working
www.irishtimes.com/health/2025/...
#Infertility #PregnancyLoss #Workplace
Ping #PLRG_PLACESproject
www.irishtimes.com/health/2025/...
#Infertility #PregnancyLoss #Workplace
Ping #PLRG_PLACESproject
Reposted by Christina Megli
#bromocriptine treatment in addition to standard of care in #PPCM was associated with better maternal outcomes
EORP PPCM registry
#CardioObstetrics #CardioSky
academic.oup.com/eurheartj/ar...
@escardio.bsky.social @isabellemalhame.bsky.social @garimasharmamd.bsky.social @mdharringtonc.bsky.social
EORP PPCM registry
#CardioObstetrics #CardioSky
academic.oup.com/eurheartj/ar...
@escardio.bsky.social @isabellemalhame.bsky.social @garimasharmamd.bsky.social @mdharringtonc.bsky.social
March 21, 2025 at 12:32 AM
#bromocriptine treatment in addition to standard of care in #PPCM was associated with better maternal outcomes
EORP PPCM registry
#CardioObstetrics #CardioSky
academic.oup.com/eurheartj/ar...
@escardio.bsky.social @isabellemalhame.bsky.social @garimasharmamd.bsky.social @mdharringtonc.bsky.social
EORP PPCM registry
#CardioObstetrics #CardioSky
academic.oup.com/eurheartj/ar...
@escardio.bsky.social @isabellemalhame.bsky.social @garimasharmamd.bsky.social @mdharringtonc.bsky.social
Reposted by Christina Megli
For those diagnosed with one of the deadliest of cancers, this could mean there’s Hope, there’s Life.
If this is stopped, the stopper & it’s comrades can rot painfully in hell.
#ProudBlue #Voices4Victory
www.nature.com/articles/s41...
If this is stopped, the stopper & it’s comrades can rot painfully in hell.
#ProudBlue #Voices4Victory
www.nature.com/articles/s41...
Fig. 1: mRNA vaccine immune response correlates with delayed PDAC recurrence at three-year follow-up. | Nature
www.nature.com
February 28, 2025 at 3:02 PM
For those diagnosed with one of the deadliest of cancers, this could mean there’s Hope, there’s Life.
If this is stopped, the stopper & it’s comrades can rot painfully in hell.
#ProudBlue #Voices4Victory
www.nature.com/articles/s41...
If this is stopped, the stopper & it’s comrades can rot painfully in hell.
#ProudBlue #Voices4Victory
www.nature.com/articles/s41...
Reposted by Christina Megli
If you have a relationship with local media, use it now!
These issues are hard to explain but critical for your neighbors to understand, looking at you Birmingham, St Louis, Philly, Baltimore, San Diego etc
These issues are hard to explain but critical for your neighbors to understand, looking at you Birmingham, St Louis, Philly, Baltimore, San Diego etc
Local traditional media still works!
We shot this interview on the grounds of the former J&L steel mill, where buildings including my lab are today. The threat to biomedical research in Pittsburgh is on par with the threat to the mills 50 years ago.
www.wtae.com/article/pitt...
We shot this interview on the grounds of the former J&L steel mill, where buildings including my lab are today. The threat to biomedical research in Pittsburgh is on par with the threat to the mills 50 years ago.
www.wtae.com/article/pitt...
Pittsburgh researcher warns NIH cuts could harm patient care, economic growth
Pittsburgh's economy once relied heavily on the steel industry, which lined Second Avenue with miles of mills. When that industry collapsed, medicine and education filled the economic void.
www.wtae.com
February 28, 2025 at 2:01 AM
If you have a relationship with local media, use it now!
These issues are hard to explain but critical for your neighbors to understand, looking at you Birmingham, St Louis, Philly, Baltimore, San Diego etc
These issues are hard to explain but critical for your neighbors to understand, looking at you Birmingham, St Louis, Philly, Baltimore, San Diego etc
Reposted by Christina Megli
The American College of Ob/Gyn’s Practice Advisory for pregnant patients during measles outbreaks
#MedHub
www.acog.org/clinical/cli...
#MedHub
www.acog.org/clinical/cli...
Management of Obstetric–Gynecologic Patients During a Measles Outbreak
This Practice Advisory was issued in response to the surge in measles cases across the United States as of March 2024. The advisory aims to provide guidance and recommendations to healthcare professio...
www.acog.org
February 28, 2025 at 5:56 PM
The American College of Ob/Gyn’s Practice Advisory for pregnant patients during measles outbreaks
#MedHub
www.acog.org/clinical/cli...
#MedHub
www.acog.org/clinical/cli...
Reposted by Christina Megli
The Biology Dept @uncchapelhill.bsky.social is searching for a Teaching Assistant Professor or Teaching Associate Professor. We're a vibrant community with fantastic colleagues and students. Apply and tell all your friends too! Here's the job posting link:
unc.peopleadmin.com/postings/297...
unc.peopleadmin.com/postings/297...
February 28, 2025 at 1:07 PM
The Biology Dept @uncchapelhill.bsky.social is searching for a Teaching Assistant Professor or Teaching Associate Professor. We're a vibrant community with fantastic colleagues and students. Apply and tell all your friends too! Here's the job posting link:
unc.peopleadmin.com/postings/297...
unc.peopleadmin.com/postings/297...
Reposted by Christina Megli
Reposted by Christina Megli
This is an amazing resource for placenta researchers! Also if you use these or other, remember to cite datasets and source code that you use in publications!
We resubmitted our paper this week! Raw data is available on GEO (GSE288650) and here's an interactive app we made so anyone can look up their favorite genes in our single nucleus placenta datasets gladfelterlab.shinyapps.io/PlacentaRNAs...
Placenta datasets from trophoblast organoids and primary human tissue
gladfelterlab.shinyapps.io
February 20, 2025 at 11:57 PM
This is an amazing resource for placenta researchers! Also if you use these or other, remember to cite datasets and source code that you use in publications!
Reposted by Christina Megli
Wow, this is really, really fascinating.
"Our approach, however, reliably predicts preeclampsia risk using cfDNA nucleosome profiling of placenta and endothelial tissue, with the addition of only two simple clinical parameters: blood pressure and BMI."
"Our approach, however, reliably predicts preeclampsia risk using cfDNA nucleosome profiling of placenta and endothelial tissue, with the addition of only two simple clinical parameters: blood pressure and BMI."
Prenatal DNA screening successfully predicts preeclampsia risk early in pregnancy, identifying tissue dysfunction months before onset.
by Adil M, Kolarova TR (...) Shree R et 15 al. in Nat Med #MedSky
📖 read the article:
by Adil M, Kolarova TR (...) Shree R et 15 al. in Nat Med #MedSky
📖 read the article:
Preeclampsia risk prediction from prenatal cell-free DNA screening - Nature Medicine
Using 1,854 routinely collected clinical samples from early in pregnancy, with validation in an external cohort, low-coverage cfDNA sequence data identified distinctive features among those who developed preeclampsia.
www.nature.com
February 21, 2025 at 6:41 PM
Wow, this is really, really fascinating.
"Our approach, however, reliably predicts preeclampsia risk using cfDNA nucleosome profiling of placenta and endothelial tissue, with the addition of only two simple clinical parameters: blood pressure and BMI."
"Our approach, however, reliably predicts preeclampsia risk using cfDNA nucleosome profiling of placenta and endothelial tissue, with the addition of only two simple clinical parameters: blood pressure and BMI."
Reposted by Christina Megli
LAST CALL on abstract submission for 2025 American Society for Reproductive Immunology meeting! Due at midnight tonight! Hope to see you all in May!
theasri.org/Abstracts-Po...
theasri.org/Abstracts-Po...
The American Society for Reproductive Immunology - Abstracts / Posters
theasri.org
February 21, 2025 at 8:22 PM
LAST CALL on abstract submission for 2025 American Society for Reproductive Immunology meeting! Due at midnight tonight! Hope to see you all in May!
theasri.org/Abstracts-Po...
theasri.org/Abstracts-Po...
www.cdc.gov/mmwr/volumes...
For anyone who needs insight into what EIS officers and CDC do! This lovely article about the Dengue outbreak in Puerto Rico describes the response.
For anyone who needs insight into what EIS officers and CDC do! This lovely article about the Dengue outbreak in Puerto Rico describes the response.
Dengue Outbreak and Response — Puerto Rico...
This report describes a local public health emergency triggered by dengue cases in Puerto Rico during 2024.
www.cdc.gov
February 20, 2025 at 6:41 PM
www.cdc.gov/mmwr/volumes...
For anyone who needs insight into what EIS officers and CDC do! This lovely article about the Dengue outbreak in Puerto Rico describes the response.
For anyone who needs insight into what EIS officers and CDC do! This lovely article about the Dengue outbreak in Puerto Rico describes the response.
Reposted by Christina Megli
DNA methylation differences between cord and adult white blood cells reflect postnatal immune cell maturation
www.nature.com/articles/s42...
www.nature.com/articles/s42...
February 14, 2025 at 11:23 PM
DNA methylation differences between cord and adult white blood cells reflect postnatal immune cell maturation
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Christina Megli
@maxplanck.de President @patrick-cramer.bsky.social is on it already.
www.spiegel.de/wissenschaft...
www.spiegel.de/wissenschaft...
February 15, 2025 at 2:12 AM
@maxplanck.de President @patrick-cramer.bsky.social is on it already.
www.spiegel.de/wissenschaft...
www.spiegel.de/wissenschaft...