PJP
@pjp04.bsky.social
ID physician and TB enthusiast.
Views my own.
Views my own.
Reposted by PJP
Very compelling study showing the association between herpes zoster vaccination and dementia prevention. The authors leveraged a unique cohort for this natural experiment which shows a reduction in dementia risk of 20% in vaccinated individuals. #MedSky #IDSky 🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
www.nature.com
April 2, 2025 at 5:49 PM
Very compelling study showing the association between herpes zoster vaccination and dementia prevention. The authors leveraged a unique cohort for this natural experiment which shows a reduction in dementia risk of 20% in vaccinated individuals. #MedSky #IDSky 🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by PJP
(🧵) Hear from our patients and specialists as they share their experiences with tuberculosis (TB).
Follow the thread 👇
Follow the thread 👇
March 25, 2025 at 7:54 PM
(🧵) Hear from our patients and specialists as they share their experiences with tuberculosis (TB).
Follow the thread 👇
Follow the thread 👇
Reposted by PJP
“In Finland, the number of homeless people has fallen sharply. Those affected receive a small apartment & counselling with no preconditions. 4 out of 5 people affected make their way back into a stable life. And all this is CHEAPER than accepting homelessness.”
Finland ends homelessness and provides shelter for all in need - scoop.me
In Finland, the number of homeless people has fallen sharply. Why? The country applies the "Housing First" concept agains homelessness.
thebetter.news
March 6, 2025 at 5:45 AM
“In Finland, the number of homeless people has fallen sharply. Those affected receive a small apartment & counselling with no preconditions. 4 out of 5 people affected make their way back into a stable life. And all this is CHEAPER than accepting homelessness.”
Reposted by PJP
PIH Sierra Leone & the Ministry of Health just opened a cutting-edge microbiology lab at Koidu Gov. Hospital!
With advanced technology and expert-led training, clinicians can now make informed decisions, reducing the misuse of antibiotics and improving patient outcomes: www.pih.org/article/loca...
With advanced technology and expert-led training, clinicians can now make informed decisions, reducing the misuse of antibiotics and improving patient outcomes: www.pih.org/article/loca...
Local Solutions for Global Impact: New Microbiology Lab Opens in Sierra Leone
The cutting-edge lab is a central hub for PIH-supported Koidu Government Hospital, providing test results for patients and clinicians across all departments.
www.pih.org
March 6, 2025 at 8:22 PM
PIH Sierra Leone & the Ministry of Health just opened a cutting-edge microbiology lab at Koidu Gov. Hospital!
With advanced technology and expert-led training, clinicians can now make informed decisions, reducing the misuse of antibiotics and improving patient outcomes: www.pih.org/article/loca...
With advanced technology and expert-led training, clinicians can now make informed decisions, reducing the misuse of antibiotics and improving patient outcomes: www.pih.org/article/loca...
Reposted by PJP
Part 2 w/ Dr. @cdmitpih.bsky.social from @harvardmed.bsky.social discusses the #endTB trial & how it’s changing RR-TB treatment with 9-month, all-oral regimens that are more affordable and accessible, along with future directions for the field. #IDsky #MEDsky
www.contagionlive.com/view/endtb-t...
www.contagionlive.com/view/endtb-t...
endTB Trial Paves Way for Shorter, Cheaper, and Safer Rifampin-Resistant TB Treatments
Carole Mitnick, ScD discusses the impact of the endTB trial's findings on future TB treatment options, including shorter treatment durations, lower costs, and expanded accessibility.
www.contagionlive.com
February 10, 2025 at 4:19 PM
Part 2 w/ Dr. @cdmitpih.bsky.social from @harvardmed.bsky.social discusses the #endTB trial & how it’s changing RR-TB treatment with 9-month, all-oral regimens that are more affordable and accessible, along with future directions for the field. #IDsky #MEDsky
www.contagionlive.com/view/endtb-t...
www.contagionlive.com/view/endtb-t...
Reposted by PJP
Thx for sharing our endTB results. Too bad u weren’t able to include my comment on the chilling effect on medical advances in TB, HIV, cancer, heart disease, etc. wrought by current US leadership. endTB was possible only bcuz of trust cultivated over decades.½
Part 2 w/ Dr. @cdmitpih.bsky.social from @harvardmed.bsky.social discusses the #endTB trial & how it’s changing RR-TB treatment with 9-month, all-oral regimens that are more affordable and accessible, along with future directions for the field. #IDsky #MEDsky
www.contagionlive.com/view/endtb-t...
www.contagionlive.com/view/endtb-t...
endTB Trial Paves Way for Shorter, Cheaper, and Safer Rifampin-Resistant TB Treatments
Carole Mitnick, ScD discusses the impact of the endTB trial's findings on future TB treatment options, including shorter treatment durations, lower costs, and expanded accessibility.
www.contagionlive.com
February 12, 2025 at 11:04 AM
Thx for sharing our endTB results. Too bad u weren’t able to include my comment on the chilling effect on medical advances in TB, HIV, cancer, heart disease, etc. wrought by current US leadership. endTB was possible only bcuz of trust cultivated over decades.½
Reposted by PJP
For those who thought TB was a disease of the past, it’s not. For those who thought TB was fully preventable & curable, it is. For those who can’t reconcile these facts & that 1.5 million people die of TB, each year…½🧵
January 28, 2025 at 9:21 PM
For those who thought TB was a disease of the past, it’s not. For those who thought TB was fully preventable & curable, it is. For those who can’t reconcile these facts & that 1.5 million people die of TB, each year…½🧵
Reposted by PJP
“We know how to live in a world without tuberculosis. But we choose to not live in that world”
I’m so excited to read @johngreensbluesky.bsky.social new book!!
Please stay tuned for my interview with John in March!
everythingistb.com
I’m so excited to read @johngreensbluesky.bsky.social new book!!
Please stay tuned for my interview with John in March!
everythingistb.com
January 26, 2025 at 5:36 PM
“We know how to live in a world without tuberculosis. But we choose to not live in that world”
I’m so excited to read @johngreensbluesky.bsky.social new book!!
Please stay tuned for my interview with John in March!
everythingistb.com
I’m so excited to read @johngreensbluesky.bsky.social new book!!
Please stay tuned for my interview with John in March!
everythingistb.com
Reposted by PJP
You can watch the Jan 23 IDSA Clinician Call on H5N1 avian influenza here: www.idsociety.org/multimedia/c...
#IDSky #MedSky #EpiSky
#IDSky #MedSky #EpiSky
Clinician Call: Update on Avian Flu
www.idsociety.org
January 25, 2025 at 3:34 AM
You can watch the Jan 23 IDSA Clinician Call on H5N1 avian influenza here: www.idsociety.org/multimedia/c...
#IDSky #MedSky #EpiSky
#IDSky #MedSky #EpiSky
Reposted by PJP
Fighting TB takes a team💪
In Lesotho, we rely on dedicated individuals known as treatment supporters to ensure TB patients stay on track with their treatment through daily home visits & connecting patients with essential resources.
Learn more about treatment supporters: www.pih.org/article/need...
In Lesotho, we rely on dedicated individuals known as treatment supporters to ensure TB patients stay on track with their treatment through daily home visits & connecting patients with essential resources.
Learn more about treatment supporters: www.pih.org/article/need...
Need to Know: Treatment Supporters
Learn why they are essential to tuberculosis care.
www.pih.org
January 23, 2025 at 8:30 PM
Fighting TB takes a team💪
In Lesotho, we rely on dedicated individuals known as treatment supporters to ensure TB patients stay on track with their treatment through daily home visits & connecting patients with essential resources.
Learn more about treatment supporters: www.pih.org/article/need...
In Lesotho, we rely on dedicated individuals known as treatment supporters to ensure TB patients stay on track with their treatment through daily home visits & connecting patients with essential resources.
Learn more about treatment supporters: www.pih.org/article/need...
Reposted by PJP
Potential impact of increasing CAB/RPV use on the future efficacy of INSTIs as first-line therapy for HIV.
#IDsky #HIVsky
@cidjournal.bsky.social
academic.oup.com/cid/advance-...
#IDsky #HIVsky
@cidjournal.bsky.social
academic.oup.com/cid/advance-...
Virologic failure and emergent integrase strand transfer inhibitor drug resistance with long acting cabotegravir for HIV treatment: A meta-analysis
Although 48-week virological failure rates were low, emergent integrase resistance among those failing injectable cabotegravir was common (41-71%), and cro
academic.oup.com
January 6, 2025 at 12:47 AM
Potential impact of increasing CAB/RPV use on the future efficacy of INSTIs as first-line therapy for HIV.
#IDsky #HIVsky
@cidjournal.bsky.social
academic.oup.com/cid/advance-...
#IDsky #HIVsky
@cidjournal.bsky.social
academic.oup.com/cid/advance-...
Reposted by PJP
"The study is impressive in its scale...cases and deaths dropped by more than 50% and in the Indigenous population the drop was even more dramatic: more than 60%."
Nature Medicine study shows the effects of Bolsa Familia strongest in Black and Indigenous populations
www.npr.org/sections/goa...
Nature Medicine study shows the effects of Bolsa Familia strongest in Black and Indigenous populations
www.npr.org/sections/goa...
Tuberculosis rates plunge when families living in poverty get a monthly cash payout
A program in Brazil that gives a monthly cash sum to families living in poverty has an unexpected — and welcome result. A new study shows that it is dramatically reducing tuberculosis rates.
www.npr.org
January 3, 2025 at 6:58 PM
"The study is impressive in its scale...cases and deaths dropped by more than 50% and in the Indigenous population the drop was even more dramatic: more than 60%."
Nature Medicine study shows the effects of Bolsa Familia strongest in Black and Indigenous populations
www.npr.org/sections/goa...
Nature Medicine study shows the effects of Bolsa Familia strongest in Black and Indigenous populations
www.npr.org/sections/goa...
Reposted by PJP
Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively".
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
On the Inpatient ID Consult Service, Oral Antibiotics Have a Rocky Road to Acceptance
Having just completed a stint doing inpatient ID consults, I came away impressed with three things: Staph aureus remains the Ruler of Evil Invasive Pathogens in the hospital setting. You can “jinx” a ...
blogs.jwatch.org
January 3, 2025 at 6:53 PM
Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively".
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Reposted by PJP
There’s a good reason why we call tuberculosis a social disease
TB rates plunge when families living in poverty get a monthly cash payout
www.npr.org/sections/goa...
TB rates plunge when families living in poverty get a monthly cash payout
www.npr.org/sections/goa...
Tuberculosis rates plunge when families living in poverty get a monthly cash payout
A program in Brazil that gives a monthly cash sum to families living in poverty has an unexpected — and welcome result. A new study shows that it is dramatically reducing tuberculosis rates.
www.npr.org
January 3, 2025 at 8:00 PM
There’s a good reason why we call tuberculosis a social disease
TB rates plunge when families living in poverty get a monthly cash payout
www.npr.org/sections/goa...
TB rates plunge when families living in poverty get a monthly cash payout
www.npr.org/sections/goa...
Reposted by PJP
Is making a difference in your community (& around the world) one of your New Year's resolutions? Join us virtually or in person for a #Tuberculosis Hill Day in April 2025! The deadline to commit is December 31: tbfighters.org/hill-day
December 30, 2024 at 12:56 AM
Is making a difference in your community (& around the world) one of your New Year's resolutions? Join us virtually or in person for a #Tuberculosis Hill Day in April 2025! The deadline to commit is December 31: tbfighters.org/hill-day
Reposted by PJP
🏥 On the fourth day of PIH, we’re celebrating a breakthrough in the fight against TB! Four new, short, and highly effective treatments from the EndTB trials have been approved by the WHO.
This marks a significant step forward in combating TB
Learn more: www.pih.org/press/major-...
This marks a significant step forward in combating TB
Learn more: www.pih.org/press/major-...
December 25, 2024 at 4:22 AM
🏥 On the fourth day of PIH, we’re celebrating a breakthrough in the fight against TB! Four new, short, and highly effective treatments from the EndTB trials have been approved by the WHO.
This marks a significant step forward in combating TB
Learn more: www.pih.org/press/major-...
This marks a significant step forward in combating TB
Learn more: www.pih.org/press/major-...
Reposted by PJP
Meet Lecsame Joseph, a dedicated farmer from Pignon, Haiti 🇭🇹
After years of working as a mechanic and taxi driver in Port-au-Prince, Joseph was diagnosed with diabetes. 🧵
After years of working as a mechanic and taxi driver in Port-au-Prince, Joseph was diagnosed with diabetes. 🧵
December 20, 2024 at 7:11 PM
Meet Lecsame Joseph, a dedicated farmer from Pignon, Haiti 🇭🇹
After years of working as a mechanic and taxi driver in Port-au-Prince, Joseph was diagnosed with diabetes. 🧵
After years of working as a mechanic and taxi driver in Port-au-Prince, Joseph was diagnosed with diabetes. 🧵
Reposted by PJP
On the third day of PIH: Discover how 3 health programs reflect Diné culture on Navajo Nation 🧡
From culturally aligned care to honoring traditions, see how health care + heritage come together for Navajo communities.
Read more: www.pih.org/article/thre...
From culturally aligned care to honoring traditions, see how health care + heritage come together for Navajo communities.
Read more: www.pih.org/article/thre...
December 23, 2024 at 2:29 PM
On the third day of PIH: Discover how 3 health programs reflect Diné culture on Navajo Nation 🧡
From culturally aligned care to honoring traditions, see how health care + heritage come together for Navajo communities.
Read more: www.pih.org/article/thre...
From culturally aligned care to honoring traditions, see how health care + heritage come together for Navajo communities.
Read more: www.pih.org/article/thre...
Reposted by PJP
Let’s kick off with Day 1: PIH Sierra Leone launched the country’s first-ever mental health hotline!
This groundbreaking initiative delivers vital mental health support to those who need it most.
Learn how this project is transforming lives: www.pih.org/article/pih-...
December 21, 2024 at 9:53 PM
Let’s kick off with Day 1: PIH Sierra Leone launched the country’s first-ever mental health hotline!
This groundbreaking initiative delivers vital mental health support to those who need it most.
Learn how this project is transforming lives: www.pih.org/article/pih-...
Reposted by PJP
Welcome to the 11 Days of PIH ❄️🎉
As the year wraps up, we celebrate the incredible impact we've achieved together. Over the next 11 days, we’ll highlight stories showcasing the work we’ve accomplished, the lives we’ve changed, and the progress we’ve driven in global health. 🧵
As the year wraps up, we celebrate the incredible impact we've achieved together. Over the next 11 days, we’ll highlight stories showcasing the work we’ve accomplished, the lives we’ve changed, and the progress we’ve driven in global health. 🧵
December 21, 2024 at 9:53 PM
Welcome to the 11 Days of PIH ❄️🎉
As the year wraps up, we celebrate the incredible impact we've achieved together. Over the next 11 days, we’ll highlight stories showcasing the work we’ve accomplished, the lives we’ve changed, and the progress we’ve driven in global health. 🧵
As the year wraps up, we celebrate the incredible impact we've achieved together. Over the next 11 days, we’ll highlight stories showcasing the work we’ve accomplished, the lives we’ve changed, and the progress we’ve driven in global health. 🧵
Reposted by PJP
📣 On the second day of PIH, we’re inviting YOU to take action! In less than two minutes, you can contact your rep and urge them to support the End TB Act.
Together, we can make strides in ending one of the world’s deadliest diseases.
Take action today: act.pih.org/end-tb-now-a...
Together, we can make strides in ending one of the world’s deadliest diseases.
Take action today: act.pih.org/end-tb-now-a...
December 23, 2024 at 2:13 AM
📣 On the second day of PIH, we’re inviting YOU to take action! In less than two minutes, you can contact your rep and urge them to support the End TB Act.
Together, we can make strides in ending one of the world’s deadliest diseases.
Take action today: act.pih.org/end-tb-now-a...
Together, we can make strides in ending one of the world’s deadliest diseases.
Take action today: act.pih.org/end-tb-now-a...
Reposted by PJP
I ❤️ science!
Bedaquiline is an amazing drug for tuberculosis, greatly shortening DR-TB treatment
But it also works for leprosy (another ancient mycobacterial infection)!
In patients with multibacillary leprosy, bedaquiline cleared M. leprae in 4 weeks
www.nejm.org/doi/full/10....
Bedaquiline is an amazing drug for tuberculosis, greatly shortening DR-TB treatment
But it also works for leprosy (another ancient mycobacterial infection)!
In patients with multibacillary leprosy, bedaquiline cleared M. leprae in 4 weeks
www.nejm.org/doi/full/10....
December 15, 2024 at 5:50 AM
I ❤️ science!
Bedaquiline is an amazing drug for tuberculosis, greatly shortening DR-TB treatment
But it also works for leprosy (another ancient mycobacterial infection)!
In patients with multibacillary leprosy, bedaquiline cleared M. leprae in 4 weeks
www.nejm.org/doi/full/10....
Bedaquiline is an amazing drug for tuberculosis, greatly shortening DR-TB treatment
But it also works for leprosy (another ancient mycobacterial infection)!
In patients with multibacillary leprosy, bedaquiline cleared M. leprae in 4 weeks
www.nejm.org/doi/full/10....
Reposted by PJP
This year, our photographers captured the heart of our work: from a canoe helping families reach hospitals in Liberia, to community health workers delivering care 📸
These are a few of the stories that made 2024 unforgettable!
Explore our favorite photos: www.pih.org/article/our-...
These are a few of the stories that made 2024 unforgettable!
Explore our favorite photos: www.pih.org/article/our-...
December 15, 2024 at 2:19 AM
This year, our photographers captured the heart of our work: from a canoe helping families reach hospitals in Liberia, to community health workers delivering care 📸
These are a few of the stories that made 2024 unforgettable!
Explore our favorite photos: www.pih.org/article/our-...
These are a few of the stories that made 2024 unforgettable!
Explore our favorite photos: www.pih.org/article/our-...
Reposted by PJP
While attention is trained on the potential infectious cause which could spread internationally, we should not ignore that food insecurity, malnutrition and lack of access to basic health needs seems to be the major driver of bad outcomes here. All social determinants of health enhanced by inequity.
"Given the clinical presentation and symptoms reported, and a number of associated deaths, acute pneumonia, influenza, COVID-19, measles and malaria are being considered as potential causal factors with malnutrition as a contributing factor."
Update on outbreak unfolding in DRC"
#IDSky #MedSky
Update on outbreak unfolding in DRC"
#IDSky #MedSky
Disease outbreak news on undiagnosed disease in #DRCongo bit.ly/3Zpj12M
December 8, 2024 at 8:17 PM
While attention is trained on the potential infectious cause which could spread internationally, we should not ignore that food insecurity, malnutrition and lack of access to basic health needs seems to be the major driver of bad outcomes here. All social determinants of health enhanced by inequity.