Mariana Pinho
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pinholab.bsky.social
Mariana Pinho
@pinholab.bsky.social
830 followers 170 following 20 posts
Full Professor at ITQB NOVA. Microbiologist. Microscopist. Bacterial Cell Biologist. Mother of 3.
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pinholab.bsky.social
Check out this tour de force by Nils Meiresonne and colleagues, establishing FLIM-FRET as a reliable way to study protein interactions in live bacteria with spatiotemporal resolution! We open the door to exploring divisome protein interactions during cell division.

www.biorxiv.org/content/10.1...
FtsW protein-protein interactions visualized in live Staphylococcus aureus cells by FLIM-FRET
The bacterial cell cycle relies on the coordinated and dynamic interactions between division proteins and those involved in peptidoglycan (PG) synthesis. However, visualizing these interactions in viv...
www.biorxiv.org
May 31, 2025 at 6:57 AM
Reposted by Mariana Pinho
henriqueslab.bsky.social
Why do lower-resolution images sometimes yield better results in deep learning for bioimaging analyses? 🤔📉

Mariana Ferreira's new preprint on #ReScale4DL explores this paradox and introduces optimal resolution design! @gomez-mariscal.bsky.social brainchild🧑‍🔬✨

Check: www.biorxiv.org/content/10.1...
April 10, 2025 at 4:46 PM
pinholab.bsky.social
We have 3 positions for students who want to start a PhD in the next 12 months. If you like advanced fluorescence microscopy techniques and S. aureus cell biology, check links and apply(April 4)

euraxess.ec.europa.eu/jobs/325394

euraxess.ec.europa.eu/jobs/325395

euraxess.ec.europa.eu/jobs/325396
March 29, 2025 at 8:18 PM
pinholab.bsky.social
All you wanted to know about chromosome segregation in Staphylococcus aureus and were afraid to ask - check our new preprint! A great collaboration with Xindan Wang´s lab!
www.biorxiv.org/content/10.1...
Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus
Research on chromosome organization and cell cycle progression in spherical bacteria, particularly Staphylococcus aureus, remains limited and fragmented. In this study, we established a working model ...
www.biorxiv.org
February 20, 2025 at 7:32 AM
Reposted by Mariana Pinho
davidroper2.bsky.social
Please repost!!!!!
Abstraction submission for the next Great Wall Symposium is now open!
Come to Sicily in September and learn the latest on bacterial cell wall biology.
thegreatwall-symposium.org/abstract-sub...
Pre-registration and Abstract Submission - The Greatwall-symposium
Registration and abstract submission open on January 15th, 2025.The organizers will select the final list of participants based on abstract submission, particularly for young scientist, and the applic...
thegreatwall-symposium.org
January 17, 2025 at 12:43 PM
Reposted by Mariana Pinho
itaiyanai.bsky.social
Can't wait for this new meeting on drug resistance and tolerance across species and diseases. A principle revealed in one system – maybe using different terminology – could be the big new idea when imported to another!
Abstract deadline in January!
s.embl.org/ees25-01 @EMBO/@embl.org
December 20, 2024 at 7:06 PM
Reposted by Mariana Pinho
veeninglab.com
Great review by @pinholab.bsky.social and Simon Foster on the current knowledge regarding growth, elongation and division of Staphylococcus aureus www.annualreviews.org/content/jour...
November 21, 2024 at 5:42 PM
pinholab.bsky.social
Super nice work from Simon Schäper showing that septal peptidoglycan synthases in S. aureus are not driven by FtsZ treadmilling. Instead they follow a one track model and their processive movement is dependent on peptidoglycan synthesis.

www.nature.com/articles/s41...
Cell constriction requires processive septal peptidoglycan synthase movement independent of FtsZ treadmilling in Staphylococcus aureus - Nature Microbiology
Single-molecule imaging reveals that peptidoglycan synthesis and synthase activity, rather than FtsZ treadmilling, are rate limiting and drive septum constriction in Staphylococcus aureus.
www.nature.com
March 13, 2024 at 11:47 AM
Reposted by Mariana Pinho
stcmicrobeblog.bsky.social
cell divisionist take note 👇

meetings.embo.org/event/24-z-r...
Archaeal and bacterial cell division: Beyond the Z-ring
The objective of this EMBO Workshop is to discuss advances in prokaryotic cell division. Most archaea and bacteria divide using a ring-structure formed by the tubulin homologue FtsZ, the Z-ring. Rese�...
meetings.embo.org
February 2, 2024 at 11:38 PM
Reposted by Mariana Pinho
seamusholden.bsky.social
Registration and abstract submission is open for Single Molecule Bacteriology III, 30 September - 3 October 2024, De Vere Cotswold Water Park, UK Outstanding speakers and delightful location eventsforce.net/biochemsoc/f...
#microsky #microscopy 🔬🦠🧫
January 31, 2024 at 10:59 AM