Pia Sen
pia-sen.bsky.social
Pia Sen
@pia-sen.bsky.social
PhD student at GWU studying the microbial ecology of extremophiles and the evolution of viruses + antiviral defenses 🦠🧫🌋
🎓UT Austin 2020
Reposted by Pia Sen
This year I submitted a big transdisciplinary grant at the end of September and have now started the new semester’s teaching. I lacked a bit of motivation to draw and started a couple of days late! If I miss any days you can check out previous October art here: elliejameson.wordpress.com/inktober/
Ink drawing challenges
During October I have been taking on an art challenge to develop drawing skills and habits through undertaking an ink drawing every day in October, based on a prompt word. After posting some microb…
elliejameson.wordpress.com
October 6, 2025 at 3:19 PM
Reposted by Pia Sen
(6/7) We highlight a few stories: evidence for retroposition into phage-specific loci, unique CapR domains not reported in group II intron-encoded homing endonucleases, and the presence of a group II intron in an annotated Inovirus, the first group II intron noted in a single stranded DNA organism.
May 24, 2025 at 7:20 PM
PHAGE ICON!!!
May 24, 2025 at 8:41 PM
Reposted by Pia Sen
(5/7) We use three lines of evidence along with Infernal hits. (1) The presence of full-length intronless homologs of genes the group II’s are inserted in. (2) Identification of pseudoknotted tertiary base-pairing not modeled by Infernal. (3) Similarity of intron-encoded ORFs to known group II ORFs.
May 24, 2025 at 7:20 PM
Reposted by Pia Sen
(4/7) Recent accelerations in Infernal, a profile SCFG-based search and alignment tool from our lab, allow us to find these large RNAs across large genomic and metagenomic datasets.
May 24, 2025 at 7:20 PM