Patrick Howlett
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phowlett.bsky.social
Patrick Howlett
@phowlett.bsky.social
He/him | MRC Clinical Research Fellow at
@imperialcollege
| Occupational lung disease and infection | Decarbonising health | ❤️🚴‍♂️🏔️ | Tweets are my own ...
❤️ 🤝 collaboration with colleagues in UCT 🇿🇦, OK International 🇺🇸 and Kibong'oto (Tanzania) 🇹🇿
March 25, 2025 at 2:08 PM
5) We can + must do more; starting with primary prevention.

Silica dust is main driver of disease

Pilot studies show levels can be ⬇️ 80-99% at low cost ($1000-5000 per mine)

What are we waiting for?

4/4

@imperialnhli.bsky.social @imperialcollegeldn.bsky.social @thelancetph.bsky.social
March 25, 2025 at 2:05 PM
3) Its under-researched; 6 basic science TB/silica papers in last 25 years... research being done largely unfunded + by in-country teams...

4) Disease has socioeconomic and political roots; mining has moved to lower income countries due to cost; demand will ⬆️ with electrification

3/4
March 25, 2025 at 2:05 PM
We argue:

1) There is a larger disease burden than we think; possibly 1 in 25 TB cases globally

2) Very high disease estimates - between 1 in 8 (!) and 1 in 50 miners having microbiological TB - are plausible given ⬆️⬆️ high silica exposures of 4 to 2400x the US max permissible exposure limits

3/4
March 25, 2025 at 2:05 PM
👋
December 14, 2024 at 12:11 AM
November 27, 2024 at 1:33 PM
Reposted by Patrick Howlett
That’s it! I hope to see you at #BTSWinter2024 Come and say hi!
21/21 /end brit-thoracic.org.uk/education-an...
BTS Winter Meeting
The Winter Meeting will be held in London from Wednesday 24th to Friday 26th November 2021.
brit-thoracic.org.uk
November 27, 2024 at 7:17 AM
Also, Demon Copperhead by Barbara Kingsolver - modern America!
November 25, 2024 at 3:21 PM
November 14, 2024 at 8:02 PM