The Polygenic Score Catalog
@pgscatalog.bsky.social
An open database of polygenic scores and the relevant metadata required for accurate application and evaluation
https://www.pgscatalog.org/
https://www.pgscatalog.org/
Stay tuned here for upcoming updates to pgsc_calc (github.com/PGScatalog/p...), our tool for reproducible PGS calculation. Our next version aims to increase the scalability to WGS data in cloud trusted research environments (e.g. All of Us).
GitHub - PGScatalog/pgsc_calc: The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation
The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation - PGScatalog/pgsc_calc
github.com
November 11, 2025 at 5:43 PM
Stay tuned here for upcoming updates to pgsc_calc (github.com/PGScatalog/p...), our tool for reproducible PGS calculation. Our next version aims to increase the scalability to WGS data in cloud trusted research environments (e.g. All of Us).
Another highlight from this release is a new score for all-cause dementia, 🔗: www.pgscatalog.org/score/PGS005.... Thanks to D'Aoust et al. for sharing!
A polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
April 17, 2025 at 11:11 AM
Another highlight from this release is a new score for all-cause dementia, 🔗: www.pgscatalog.org/score/PGS005.... Thanks to D'Aoust et al. for sharing!
Also out today is this multi-ancestry PGS for PSA! 🔗: www.pgscatalog.org/publication/...
📣 Happy to share our latest paper - an exciting step forward for PSA genetics with a much larger and more diverse GWAS and a more predictive PGS ⚡️
@johnwitte.bsky.social
@stanford-cancer.bsky.social
@stanfordmedicine.bsky.social
@johnwitte.bsky.social
@stanford-cancer.bsky.social
@stanfordmedicine.bsky.social
📢ONLINE @naturegenet.bsky.social
📰Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups.
By Thomas Hoffmann, @lindakachuri.bsky.social, @johnwitte.bsky.social and co.
⬇️
www.nature.com/articles/s41...
📰Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups.
By Thomas Hoffmann, @lindakachuri.bsky.social, @johnwitte.bsky.social and co.
⬇️
www.nature.com/articles/s41...
February 26, 2025 at 2:44 PM
Also out today is this multi-ancestry PGS for PSA! 🔗: www.pgscatalog.org/publication/...
The Catalog isn't just a knowledgebase and source of polygenic scores, we also provide open-soruce tools to make PGS calculation easier and more reproducible! You can find our pgsc_calc tool on github (github.com/PGScatalog/p...) with extensive documentation (pgsc-calc.readthedocs.io/en/latest/).
November 26, 2024 at 12:30 PM
The Catalog isn't just a knowledgebase and source of polygenic scores, we also provide open-soruce tools to make PGS calculation easier and more reproducible! You can find our pgsc_calc tool on github (github.com/PGScatalog/p...) with extensive documentation (pgsc-calc.readthedocs.io/en/latest/).