Penny Lewthwaite
pennylewthwaite.bsky.social
Penny Lewthwaite
@pennylewthwaite.bsky.social
Infectious Diseases Doc. Views my own..
Reposted by Penny Lewthwaite
First paper to share here

Delightful to have been part of the all new UK guidelines on the diagnosis of and management of eosinophilia!

www.journalofinfection.com/article/S016...
UK guidelines for the investigation and management of eosinophilia in returning travellers and migrants
Eosinophilia is a common finding in returning travellers, migrants and other travelling groups. In this setting it often indicates an underlying helminth infection. Infections associated with eosinoph...
www.journalofinfection.com
November 12, 2024 at 10:51 PM
Reposted by Penny Lewthwaite
www.thelancet.com/journals/lan...

@thelancetinfdis full of interesting emerging virus information this month.

Interesting article on PLWH, mpox and tecivorimat resistance
Mpox outbreak—tecovirimat resistance, management approaches, and challenges in HIV-endemic regions
Mpox is a viral infection that causes acute disease in humans and can be fatal. On Aug 14, 2024, the WHO declared the ongoing mpox outbreak to be a global public health emergency. Shifting transmissio...
www.thelancet.com
November 8, 2024 at 6:35 PM
Reposted by Penny Lewthwaite
Diagnostic accuracy of three mpox lateral flow assays for antigen detection in the Democratic Republic of Congo and the United Kingdom https://www.medrxiv.org/content/10.1101/2024.11.07.24316894v1
Diagnostic accuracy of three mpox lateral flow assays for antigen detection in the Democratic Republic of Congo and the United Kingdom https://www.medrxiv.org/content/10.1101/2024.11.07.24316894v1
Background: The ongoing outbreaks of mpox, the disease caused by monkeypox virus (MPXV) highlight th
www.medrxiv.org
November 8, 2024 at 11:44 PM
Reposted by Penny Lewthwaite
When it rains it pours: Rwanda reports finding an unspecified number of #Marburg cases in "health facilities" — note that's plural — in the country.
Do not like the look of this.
September 27, 2024 at 2:31 PM
Reposted by Penny Lewthwaite
1. Rwanda's first detected #Marburg outbreak is already the 4th (maybe really the 5th) largest Marburg outbreak ever. Stunning to see 26 cases & 6 deaths already; those numbers reflect spread in healthcare settings. Hopefully they get a handle on this quickly. www.afro.who.int/countries/rw...
Rwanda reports first-ever Marburg virus disease outbreak, with 26 cases confirmed
Brazzaville/Kigali – Rwandan health authorities are intensifying outbreak control efforts following the detection of Marburg virus disease, with 26 cases confirmed and six deaths reported currently.
www.afro.who.int
September 28, 2024 at 10:30 PM
Reposted by Penny Lewthwaite
🆕 Our commentary in Lancet ID: “The worsening mpox outbreak in Africa: a call to action.”

Urgent action is needed to:
1. Scale up testing/surveillance
2. Study research gaps
3. Invest in vaccines/therapeutics
4. Boost care quality
5. Tailor community outreach

www.thelancet.com/journals/lan...
The worsening mpox outbreak in Africa: a call to action
The escalating incidence of mpox in Africa has led the Africa Centres for Disease Control and Prevention to declare its first-ever Public Health Emergency of Continental Security and prompted WHO to i...
www.thelancet.com
September 11, 2024 at 4:02 AM
Reposted by Penny Lewthwaite
“Nigeria today received 10,000 doses of mpox vaccines, becoming the first country in the African region to receive doses to respond to the outbreak of the viral disease that has affected several countries.”

https://www.afro.who.int/countries/nigeria/news/first-ever-delivery-mpox-vaccines-africa-ou…
First-ever delivery of mpox vaccines in Africa outside of clinical trials arrives in Nigeria
Nigeria today received 10 000 doses of mpox vaccines, becoming the first country in the African region to receive doses to respond to the outbreak of the viral disease that has affected several…
buff.ly
August 28, 2024 at 6:09 PM
Reposted by Penny Lewthwaite
One of the reasons I've been quiet on Bluesky for a few months is because I've been working on something big - something I'm really happy to share now! Pathoplexus.org
A new, open-source database for pathogen sequence sharing. 👐🧬🌎

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Pathoplexus| Home
Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.
Pathoplexus.org
August 27, 2024 at 9:11 PM
Reposted by Penny Lewthwaite
Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles

www.nature.com/articles/s41...
Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles - Nature Communications
Current guidelines recommend that individuals exposed to mpox should isolate for three weeks, based on the average estimated incubation period. Here, the authors use a quantitative model to characteri...
www.nature.com
August 26, 2024 at 2:33 PM
Reposted by Penny Lewthwaite
A new short piece by me in the BMJ reflecting on the Covid-19 Inquiry Module 1 report and how "emergency planning" needs to be incorporated into "everyday planning"

www.bmj.com/content/386/...
Making pandemic planning part of the everyday
Health in all policies is also emergency preparedness in all policies, writes Christina Pagel The UK Covid-19 inquiry’s module 1 report on the resilience and preparedness of the UK had “no hesitation...
www.bmj.com
August 22, 2024 at 2:11 PM
Reposted by Penny Lewthwaite
jackpot

#mpox
August 23, 2024 at 8:56 AM
Reposted by Penny Lewthwaite
New WHO position paper on smallpox and mpox vaccines.

Via Rosamund Lewis from X.

iris.who.int/bitstream/ha...
iris.who.int
August 24, 2024 at 9:48 AM
Reposted by Penny Lewthwaite
Hot off the press. Thailands case of mpox is in fact the new viriulent strain of Clade 1b. They're now tracking down his contacts and those sitting close to him on the plane. Fingers crossed this has been contained. (71) www.bbc.co.uk/news/article...
Mpox: Thailand confirms Clade 1b strain for first time in Asia
The European man flew into Thailand from an unnamed African country last week, officials say.
www.bbc.co.uk
August 22, 2024 at 1:09 PM