Gert Marais
@passtheoxidase.bsky.social
Clinical Microbiologist, Virologist. Crick Africa Network Fellow. Research and interest lies in Bioinformatics. Based at the University of Cape Town, South Africa. Views my own.
Just found out you can view your calculator app history. My 3rd grade teacher would not be proud of what I found there 🫣
May 11, 2025 at 3:36 PM
Just found out you can view your calculator app history. My 3rd grade teacher would not be proud of what I found there 🫣
Reposted by Gert Marais
New this week in ICHE: Multisociety guidelines on sterilization & high-level disinfection
Developed by SHEA, APIC, @idsainfo.bsky.social, & others, this guidance updates best practices across devices, settings, and standards aligned with latest CDC updates
#IDSky
📄: doi.org/10.1017/ice....
Developed by SHEA, APIC, @idsainfo.bsky.social, & others, this guidance updates best practices across devices, settings, and standards aligned with latest CDC updates
#IDSky
📄: doi.org/10.1017/ice....
May 1, 2025 at 5:34 PM
New this week in ICHE: Multisociety guidelines on sterilization & high-level disinfection
Developed by SHEA, APIC, @idsainfo.bsky.social, & others, this guidance updates best practices across devices, settings, and standards aligned with latest CDC updates
#IDSky
📄: doi.org/10.1017/ice....
Developed by SHEA, APIC, @idsainfo.bsky.social, & others, this guidance updates best practices across devices, settings, and standards aligned with latest CDC updates
#IDSky
📄: doi.org/10.1017/ice....
Reposted by Gert Marais
In case you missed it: Study shows that children with invasive candidiasis have equally successful outcomes when transitioning from IV to enteral antifungals, helping reduce the risks of infection, costs, & hospital stays. #Pedssky #IDsky #MEDsky #AMR #fungal
www.contagionlive.com/view/childre...
www.contagionlive.com/view/childre...
Children with Invasive Candidiasis Do Well After Switching IV Antifungal to Enteral
Children with invasive candidiasis had successful outcome whether IV antifungal treatment was completed or converted to enteral to reduce risk of infusion site infections and costs.
www.contagionlive.com
February 5, 2025 at 5:04 PM
Reposted by Gert Marais
Good piece of molecular detective work on fluconazole resistant Candida parapsillosis in @bsacandjac.bsky.social
@cmcurtis.bsky.social 👍
#IDSky #ClinMicro #AMR
academic.oup.com/jac/advance-...
@cmcurtis.bsky.social 👍
#IDSky #ClinMicro #AMR
academic.oup.com/jac/advance-...
Cluster of clonal fluconazole-resistant Candida parapsilosis harbouring Y132F mutation in ERG11 gene in a neonatal ICU in the UK
Candida parapsilosis is one of the commonest causes of life-threatening Candida bloodstream infections globally.1,2 Patients admitted to ICUs, premature ne
academic.oup.com
February 1, 2025 at 5:11 PM
Good piece of molecular detective work on fluconazole resistant Candida parapsillosis in @bsacandjac.bsky.social
@cmcurtis.bsky.social 👍
#IDSky #ClinMicro #AMR
academic.oup.com/jac/advance-...
@cmcurtis.bsky.social 👍
#IDSky #ClinMicro #AMR
academic.oup.com/jac/advance-...
Reposted by Gert Marais
🧫🧪🔬🧬 The lack of theoretical, experimental and regulatory standards to assess the "beneficial" effects of 🦠 in complex host-associated microbiomes is out of control.
If papers with improper controls, minuscule effect sizes and misintterpreted data pile up, cleaning up will be impossible!
If papers with improper controls, minuscule effect sizes and misintterpreted data pile up, cleaning up will be impossible!
January 11, 2025 at 10:30 PM
🧫🧪🔬🧬 The lack of theoretical, experimental and regulatory standards to assess the "beneficial" effects of 🦠 in complex host-associated microbiomes is out of control.
If papers with improper controls, minuscule effect sizes and misintterpreted data pile up, cleaning up will be impossible!
If papers with improper controls, minuscule effect sizes and misintterpreted data pile up, cleaning up will be impossible!
Reposted by Gert Marais
Letter indicates resistance to shorter and less toxic drug regimens for multidrug-resistant tuberculosis (MDR-TB) is emerging and spreading between patients.
#IDSky
#TB
www.nejm.org/doi/10.1056/...
#IDSky
#TB
www.nejm.org/doi/10.1056/...
Transmission as a Key Driver of Resistance to the New Tuberculosis Drugs | NEJM
Whole-genome sequencing was used to show that resistance to newer antituberculosis drugs is present in at least 27 countries and that up to a quarter of this resistance may be due to person-to-...
www.nejm.org
January 11, 2025 at 2:02 PM
Letter indicates resistance to shorter and less toxic drug regimens for multidrug-resistant tuberculosis (MDR-TB) is emerging and spreading between patients.
#IDSky
#TB
www.nejm.org/doi/10.1056/...
#IDSky
#TB
www.nejm.org/doi/10.1056/...
Reposted by Gert Marais
Lenacapavir for HIV Preexposure Prophylaxis
- a Journal 🧵
In a randomized trial involving men and transgender people, twice-yearly lenacapavir (LEN) was highly efficacious at preventing HIV acquisition
#IDSKy
#HIV
(Kelley CF et al. N Engl J Med 2024 Nov 27)
doi.org/10.1056/NEJM...
- a Journal 🧵
In a randomized trial involving men and transgender people, twice-yearly lenacapavir (LEN) was highly efficacious at preventing HIV acquisition
#IDSKy
#HIV
(Kelley CF et al. N Engl J Med 2024 Nov 27)
doi.org/10.1056/NEJM...
Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons | NEJM
Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention
of HIV infection in cisgender women. The efficacy of lenacapavir for preexposure prophylaxis
(PrEP) in cisgende...
doi.org
January 11, 2025 at 2:52 PM
Lenacapavir for HIV Preexposure Prophylaxis
- a Journal 🧵
In a randomized trial involving men and transgender people, twice-yearly lenacapavir (LEN) was highly efficacious at preventing HIV acquisition
#IDSKy
#HIV
(Kelley CF et al. N Engl J Med 2024 Nov 27)
doi.org/10.1056/NEJM...
- a Journal 🧵
In a randomized trial involving men and transgender people, twice-yearly lenacapavir (LEN) was highly efficacious at preventing HIV acquisition
#IDSKy
#HIV
(Kelley CF et al. N Engl J Med 2024 Nov 27)
doi.org/10.1056/NEJM...
Reposted by Gert Marais
#AMR is a risk to antibiotic failure & death, but if this happens, do we record it on death certificates? Our centre data = NO!
👉In 1 year, 4% of deaths were AMR-attributed & NONE were recorded on death certificates!👈
Need to quantify this better to increase awareness! #IDSky @jac-amr.bsky.social
👉In 1 year, 4% of deaths were AMR-attributed & NONE were recorded on death certificates!👈
Need to quantify this better to increase awareness! #IDSky @jac-amr.bsky.social
Antimicrobial resistance–attributable mortality: a patient-level analysis
AbstractBackground. The impact of antimicrobial resistance (AMR) on death at the patient level is challenging to estimate. We aimed to characterize AMR-att
academic.oup.com
January 8, 2025 at 3:22 PM
#AMR is a risk to antibiotic failure & death, but if this happens, do we record it on death certificates? Our centre data = NO!
👉In 1 year, 4% of deaths were AMR-attributed & NONE were recorded on death certificates!👈
Need to quantify this better to increase awareness! #IDSky @jac-amr.bsky.social
👉In 1 year, 4% of deaths were AMR-attributed & NONE were recorded on death certificates!👈
Need to quantify this better to increase awareness! #IDSky @jac-amr.bsky.social
Reposted by Gert Marais
New BacDive publication is out 📄
Read about all news and updates of BacDive 🦠, the leading database for prokaryotic strain data! 2.6 million data points on 97,334 strains, a new SPARQL ✨ endpoint, genome-based predictions 🖥️🧬 and more.
#DSMZDigitalDiversity #science 🧪 #databases #FAIRdata
Read about all news and updates of BacDive 🦠, the leading database for prokaryotic strain data! 2.6 million data points on 97,334 strains, a new SPARQL ✨ endpoint, genome-based predictions 🖥️🧬 and more.
#DSMZDigitalDiversity #science 🧪 #databases #FAIRdata
BacDive in 2025: the core database for prokaryotic strain data
Abstract. In 2025, the bacterial diversity database BacDive is the leading database for strain-level bacterial and archaeal information. It has been select
academic.oup.com
November 4, 2024 at 9:25 AM
New BacDive publication is out 📄
Read about all news and updates of BacDive 🦠, the leading database for prokaryotic strain data! 2.6 million data points on 97,334 strains, a new SPARQL ✨ endpoint, genome-based predictions 🖥️🧬 and more.
#DSMZDigitalDiversity #science 🧪 #databases #FAIRdata
Read about all news and updates of BacDive 🦠, the leading database for prokaryotic strain data! 2.6 million data points on 97,334 strains, a new SPARQL ✨ endpoint, genome-based predictions 🖥️🧬 and more.
#DSMZDigitalDiversity #science 🧪 #databases #FAIRdata
Reposted by Gert Marais
We’ve just published a comprehensive list of bioinformatics resources. Thanks to @kateduncan.bsky.social and @andytruman4.bsky.social for compiling this list: actinobase.org/index.php?ti...
Bioinformatics - ActinoBase
actinobase.org
November 14, 2024 at 11:34 AM
We’ve just published a comprehensive list of bioinformatics resources. Thanks to @kateduncan.bsky.social and @andytruman4.bsky.social for compiling this list: actinobase.org/index.php?ti...
Reposted by Gert Marais
Another #IDSky journal is here!
Welcome to @jac-amr.bsky.social!
(under auspices of @bsacandjac.bsky.social )
#AMR #microsky
Welcome to @jac-amr.bsky.social!
(under auspices of @bsacandjac.bsky.social )
#AMR #microsky
November 23, 2024 at 10:33 PM
Another #IDSky journal is here!
Welcome to @jac-amr.bsky.social!
(under auspices of @bsacandjac.bsky.social )
#AMR #microsky
Welcome to @jac-amr.bsky.social!
(under auspices of @bsacandjac.bsky.social )
#AMR #microsky