@paolosti.bsky.social
Marie Skłodowska-Curie Fellow, working with func-metabo-lab and Kemen Lab, exploring plant-microbial communities via multi-omics approaches.
Reposted
This paper represents a great effort by @roman-bushuiev.bsky.social and his brother @anton-bushuiev.bsky.social. The DreaMS foundation model for mass spectra of small molecules now opens lots of avenues for possible downstream applications. It might be a game changer for computational metabolomics.
Self-supervised learning of molecular representations from millions of tandem mass spectra using DreaMS - @pluskal-lab.org @iocbprague.bsky.social go.nature.com/4k1n5iC
Self-supervised learning of molecular representations from millions of tandem mass spectra using DreaMS - Nature Biotechnology
A transformer model is used to construct the DreaMS Atlas—a molecular network of 201 million MS/MS spectra.
go.nature.com
May 24, 2025 at 8:21 AM
This paper represents a great effort by @roman-bushuiev.bsky.social and his brother @anton-bushuiev.bsky.social. The DreaMS foundation model for mass spectra of small molecules now opens lots of avenues for possible downstream applications. It might be a game changer for computational metabolomics.
Reposted
We are pretty stoked that our paper on chemical shifts in kelp forests in the Gulf of Maine made it onto the front cover of @science.org
Big congratulations to Shane Farrell and everybody involved! ✌️✌️✌️
Big congratulations to Shane Farrell and everybody involved! ✌️✌️✌️
Kelp forests on the coast of Maine are in decline owing to rapid ocean warming and are being replaced by turf algae, which alter the ecosystem’s chemistry, hindering the recovery of kelp forests.
Learn more in this week's issue of Science: scim.ag/4dwzl8j
Learn more in this week's issue of Science: scim.ag/4dwzl8j
May 22, 2025 at 11:03 PM
We are pretty stoked that our paper on chemical shifts in kelp forests in the Gulf of Maine made it onto the front cover of @science.org
Big congratulations to Shane Farrell and everybody involved! ✌️✌️✌️
Big congratulations to Shane Farrell and everybody involved! ✌️✌️✌️
Reposted
Die Universität Tübingen erhält sechs #Exzellenzcluster, die im Rahmen der #Exzellenzstrategie vom 01.01.2026 an sieben Jahre lang gefördert werden! Darunter drei Cluster, die bereits etabliert sind und eine erneute Förderung erhalten. uni-tuebingen.de/universitaet... #ExStra #Forschung #UniTübingen
May 22, 2025 at 5:13 PM
Die Universität Tübingen erhält sechs #Exzellenzcluster, die im Rahmen der #Exzellenzstrategie vom 01.01.2026 an sieben Jahre lang gefördert werden! Darunter drei Cluster, die bereits etabliert sind und eine erneute Förderung erhalten. uni-tuebingen.de/universitaet... #ExStra #Forschung #UniTübingen
Reposted
Kelp forests on the coast of Maine are in decline owing to rapid ocean warming and are being replaced by turf algae, which alter the ecosystem’s chemistry, hindering the recovery of kelp forests.
Learn more in this week's issue of Science: scim.ag/4dwzl8j
Learn more in this week's issue of Science: scim.ag/4dwzl8j
May 22, 2025 at 6:05 PM
Kelp forests on the coast of Maine are in decline owing to rapid ocean warming and are being replaced by turf algae, which alter the ecosystem’s chemistry, hindering the recovery of kelp forests.
Learn more in this week's issue of Science: scim.ag/4dwzl8j
Learn more in this week's issue of Science: scim.ag/4dwzl8j
Reposted
Biology is so cool
- P. syringae produces syringafactin, which is deacylated by amoebae
- Deacylated syringafactin binds to CraR, triggering amoebicidal pyrofactin synthesis
- Cra allows P. syringae to infect Arabidopsis thaliana in the presence of amoebae
#MicroSky
- P. syringae produces syringafactin, which is deacylated by amoebae
- Deacylated syringafactin binds to CraR, triggering amoebicidal pyrofactin synthesis
- Cra allows P. syringae to infect Arabidopsis thaliana in the presence of amoebae
#MicroSky
A chemical radar allows bacteria to detect and kill predators
Pseudomonas syringae can detect and kill microbial predators via a chemical radar
(Cra), which also allows the bacterium to infect plants despite predation pressure.
www.cell.com
April 5, 2025 at 1:13 PM
Biology is so cool
- P. syringae produces syringafactin, which is deacylated by amoebae
- Deacylated syringafactin binds to CraR, triggering amoebicidal pyrofactin synthesis
- Cra allows P. syringae to infect Arabidopsis thaliana in the presence of amoebae
#MicroSky
- P. syringae produces syringafactin, which is deacylated by amoebae
- Deacylated syringafactin binds to CraR, triggering amoebicidal pyrofactin synthesis
- Cra allows P. syringae to infect Arabidopsis thaliana in the presence of amoebae
#MicroSky
Reposted
Happy to share our paper from a new research line led by @camolsan.bsky.social, where we engineered the T6SS of Pseudomonas putida to deliver effectors against bacterial competitors and fungal pathogens like Botrytis cinerea. @ihsmumacsic.bsky.social
jbioleng.biomedcentral.com/articles/10....
jbioleng.biomedcentral.com/articles/10....
Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors - Journal of Biological Engineering
Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine...
jbioleng.biomedcentral.com
April 3, 2025 at 6:00 PM
Happy to share our paper from a new research line led by @camolsan.bsky.social, where we engineered the T6SS of Pseudomonas putida to deliver effectors against bacterial competitors and fungal pathogens like Botrytis cinerea. @ihsmumacsic.bsky.social
jbioleng.biomedcentral.com/articles/10....
jbioleng.biomedcentral.com/articles/10....
Reposted
Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social
Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium - Nature Microbiology
Genomic and functional analyses of healthcare-associated vancomycin-resistant Enterococcus faecium reveal that bacteriocin T8 is enriched in emergent lineages and provides a competitive advantage in v...
www.nature.com
March 21, 2025 at 1:46 PM
Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social
Reposted
February 24, 2025 at 6:28 PM
Reposted
Composing a microbial symphony: synthetic communities for promoting plant growth
Composing a microbial symphony: synthetic communities for promoting plant growth
Plant microbiomes are pivotal for host development, influencing growth, health, fitness, and evolution, and have emerged as promising resources for sustainable agriculture. However, leveraging these microbiomes to improve crop yield and resilience is…
dlvr.it
February 18, 2025 at 12:37 AM
Composing a microbial symphony: synthetic communities for promoting plant growth
Reposted
We will be hosting the first @mzmine.bsky.social Community Meeting at @iocbprague.bsky.social. Please register if you wish to learn about the latest developments in mzmine. More info: docs.google.com/document/d/1...
February 17, 2025 at 4:21 PM
We will be hosting the first @mzmine.bsky.social Community Meeting at @iocbprague.bsky.social. Please register if you wish to learn about the latest developments in mzmine. More info: docs.google.com/document/d/1...
Reposted
New preprint from our collaboration with @aliciaperezlorente.bsky.social from Diego Romero's group, who spend some time with us at @cmfi.bsky.social. It's great to see all the puzzle pieces coming together, providing a detailed snapshot of the molecular interplay between Bacillus and and Botrytis.
February 12, 2025 at 1:18 AM
New preprint from our collaboration with @aliciaperezlorente.bsky.social from Diego Romero's group, who spend some time with us at @cmfi.bsky.social. It's great to see all the puzzle pieces coming together, providing a detailed snapshot of the molecular interplay between Bacillus and and Botrytis.
Reposted
Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
🔗
www.biorxiv.org/content/10.1...
🔗
www.biorxiv.org/content/10.1...
The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi
Bacterial□fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix (ECM) in shaping these relationships has remained unclear....
www.biorxiv.org
February 11, 2025 at 8:01 AM
Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
🔗
www.biorxiv.org/content/10.1...
🔗
www.biorxiv.org/content/10.1...