Nozomu Yachie
@nzmyachie.bsky.social
Professor at the University of British Columbia @sbmeubc.bsky.social
Specially Appointed Professor at Osaka University PRIMe
https://yachie-lab.org
Specially Appointed Professor at Osaka University PRIMe
https://yachie-lab.org
UBC Biomedical Engineering and BC Cancer have just launched the call for the Dr. Connie Eaves Chair (Professor or Associate Professor). Engineering biology aspects are flourishing remarkably in Vancouver. Amazing research environment👋 ubc.wd10.myworkdayjobs.com/ubcfacultyjo...
Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research
Academic Job Category Faculty Bargaining Job Title Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research Department School of Biomedical Engineering | ...
ubc.wd10.myworkdayjobs.com
November 19, 2025 at 4:28 PM
UBC Biomedical Engineering and BC Cancer have just launched the call for the Dr. Connie Eaves Chair (Professor or Associate Professor). Engineering biology aspects are flourishing remarkably in Vancouver. Amazing research environment👋 ubc.wd10.myworkdayjobs.com/ubcfacultyjo...
Update: now Samantha Morris is on board too!
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026.
massivconference.com
Abstract deadline: Nov 14
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026.
massivconference.com
Abstract deadline: Nov 14
November 1, 2025 at 11:36 PM
Update: now Samantha Morris is on board too!
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026.
massivconference.com
Abstract deadline: Nov 14
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026.
massivconference.com
Abstract deadline: Nov 14
Reposted by Nozomu Yachie
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
October 25, 2025 at 4:21 PM
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
October 25, 2025 at 4:21 PM
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Please RP! A 4-day synbio and tissue engineering conference #MASSIV to transform biology and medicine together.
Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/
Poster due is Nov 7, but will be extended.
With @stemcellnetwork.ca and JST.
Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/
Poster due is Nov 7, but will be extended.
With @stemcellnetwork.ca and JST.
October 18, 2025 at 5:50 PM
Please RP! A 4-day synbio and tissue engineering conference #MASSIV to transform biology and medicine together.
Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/
Poster due is Nov 7, but will be extended.
With @stemcellnetwork.ca and JST.
Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/
Poster due is Nov 7, but will be extended.
With @stemcellnetwork.ca and JST.
I am excited to be the co-chair of #ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org
ISSCR 2026
An international gathering of the brightest minds in stem cell research and regenerative medicine across disciplines. Join us for the 2026 ISSCR Annual Meeting 8-11 July 2026 in Montréal, Canada.
www.isscr2026.org
October 17, 2025 at 1:16 AM
I am excited to be the co-chair of #ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org
I am excited to be the co-chair of hashtag#ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org
ISSCR 2026
An international gathering of the brightest minds in stem cell research and regenerative medicine across disciplines. Join us for the 2026 ISSCR Annual Meeting 8-11 July 2026 in Montréal, Canada.
www.isscr2026.org
October 16, 2025 at 11:39 PM
I am excited to be the co-chair of hashtag#ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org
Reposted by Nozomu Yachie
Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis go.nature.com/4lLtIX8
Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis - Nature Biotechnology
Transcriptome-scale maps of RNA secondary structure ensembles in living cells detect candidate RNA structural switches.
go.nature.com
July 25, 2025 at 7:26 PM
Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis go.nature.com/4lLtIX8
Photos from a life sciences roundtable on June 4 with BC Premier David Eby @davidebybc.bsky.social at #CanadaPavilion of #Expo2025Osaka. Manu Madhav, Gail Murphy, and I joined from UBC. @sbmeubc.bsky.social
July 10, 2025 at 11:46 PM
Photos from a life sciences roundtable on June 4 with BC Premier David Eby @davidebybc.bsky.social at #CanadaPavilion of #Expo2025Osaka. Manu Madhav, Gail Murphy, and I joined from UBC. @sbmeubc.bsky.social
#ISSCR2026 @isscr.org plenary and invited speakers have revealed! Please plan to submit an abstract and join us in Montreal! www.isscr2026.org/speakers
speakers — ISSCR 2026
www.isscr2026.org
June 26, 2025 at 9:32 PM
#ISSCR2026 @isscr.org plenary and invited speakers have revealed! Please plan to submit an abstract and join us in Montreal! www.isscr2026.org/speakers
CAGT was fun! Thanks @carldeboer.bsky.social @sudpinglay.bsky.social and the de Boer lab for organizing! Folks from Seattle, Oregon, and other places. Great community. Arman gave a usual super talk, and Sanchit and Dayag won poster prizes☺️
June 20, 2025 at 10:17 PM
CAGT was fun! Thanks @carldeboer.bsky.social @sudpinglay.bsky.social and the de Boer lab for organizing! Folks from Seattle, Oregon, and other places. Great community. Arman gave a usual super talk, and Sanchit and Dayag won poster prizes☺️
Reposted by Nozomu Yachie
The latest work from my lab, Phage Disco, a method
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...
Phage DisCo: targeted discovery of bacteriophages by co-culture | mSystems
In this work, we describe a targeted phage discovery method that allows immediate
isolation of phages with specific traits. Currently, to find a phage with specific
properties, huge libraries of phage...
journals.asm.org
May 29, 2025 at 2:17 AM
The latest work from my lab, Phage Disco, a method
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...
Reposted by Nozomu Yachie
+Humbled by how beautifully this animated version of this week’s @nature.com cover captures two major themes of our paper – mycorrhizal fungi and the ‘wave nature of life’.
March 9, 2025 at 3:41 PM
+Humbled by how beautifully this animated version of this week’s @nature.com cover captures two major themes of our paper – mycorrhizal fungi and the ‘wave nature of life’.
Reposted by Nozomu Yachie
A multi-kingdom genetic barcoding system for precise clone isolation - @nzmyachie.bsky.social go.nature.com/4ksLOMD
A multi-kingdom genetic barcoding system for precise clone isolation - Nature Biotechnology
A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.
go.nature.com
May 21, 2025 at 3:30 PM
A multi-kingdom genetic barcoding system for precise clone isolation - @nzmyachie.bsky.social go.nature.com/4ksLOMD
CloneSelect published in Nature Biotechnology
@natbiotech.nature.com. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of Soh in the Yachie lab. www.nature.com/articles/s41...
@natbiotech.nature.com. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of Soh in the Yachie lab. www.nature.com/articles/s41...
A multi-kingdom genetic barcoding system for precise clone isolation - Nature Biotechnology
A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.
www.nature.com
May 21, 2025 at 1:56 PM
CloneSelect published in Nature Biotechnology
@natbiotech.nature.com. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of Soh in the Yachie lab. www.nature.com/articles/s41...
@natbiotech.nature.com. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of Soh in the Yachie lab. www.nature.com/articles/s41...
Please plan to join us in Montréal🇨🇦 Excited to co-chair the program committee of #ISSCR2026 with @doetschlab.bsky.social. We have reorganized the concurrent themes. An exciting lineup of invited speakers will be announced soon.
🔬🍁Save the date! Join the global stem cell community in Montréal, Canada from 8-11 July 2026 for the #ISSCR2026 Annual Meeting. Together, we will explore the full spectrum of stem cell science and regenerative medicine. 👉 isscr2026.org
May 6, 2025 at 6:21 PM
Please plan to join us in Montréal🇨🇦 Excited to co-chair the program committee of #ISSCR2026 with @doetschlab.bsky.social. We have reorganized the concurrent themes. An exciting lineup of invited speakers will be announced soon.
I’m excited to share that we will be hosting Justin English @sbmeubc.bsky.social this Friday! Many cool synthetic biology and high-throughput screening stories are happening in his lab. His talk will be at the Life Science Institute building LSC 1002 from 11 am. Please come join us!
March 11, 2025 at 5:44 PM
I’m excited to share that we will be hosting Justin English @sbmeubc.bsky.social this Friday! Many cool synthetic biology and high-throughput screening stories are happening in his lab. His talk will be at the Life Science Institute building LSC 1002 from 11 am. Please come join us!
Poster submission is open now!👋 We are organizing the 54th Naito Conference on Genome Editing. Gorgeous speakers, including Feng Zhang, Patrick Hsu, @leopoldparts.bsky.social, Silvana Konermann, Mike Bassik, Ailong Ke, Wenning Qin, Henry Kim, Caixia Gao, Pietro Genovese, and Virginijus Siksnys.
February 18, 2025 at 5:26 PM
Poster submission is open now!👋 We are organizing the 54th Naito Conference on Genome Editing. Gorgeous speakers, including Feng Zhang, Patrick Hsu, @leopoldparts.bsky.social, Silvana Konermann, Mike Bassik, Ailong Ke, Wenning Qin, Henry Kim, Caixia Gao, Pietro Genovese, and Virginijus Siksnys.
Reposted by Nozomu Yachie
Special thanks to @nzmyachie.bsky.social and Brett Kiyota for this great collab! Preprint: www.biorxiv.org/content/10.1...
Detecting and avoiding homology-based data leakage in genome-trained sequence models
Models that predict function from DNA sequence have become critical tools in deciphering the roles of genomic sequences and genetic variation within them. However, traditional approaches for dividing ...
www.biorxiv.org
January 27, 2025 at 11:48 PM
Special thanks to @nzmyachie.bsky.social and Brett Kiyota for this great collab! Preprint: www.biorxiv.org/content/10.1...
Reposted by Nozomu Yachie
My research aims to make so much synthetic gene regulatory data that we no longer need to train models on genomic sequences (elaborated on here www.nature.com/articles/s41...), but we still lack the needed synthetic data. hashFrag is the stopgap needed to enable genome-training without leakage.
Hold out the genome: a roadmap to solving the cis-regulatory code - Nature
A roadmap towards solving the cis-regulatory code using a combination of machine learning and massively parallel assays of exogenous DNA is proposed.
www.nature.com
January 27, 2025 at 11:48 PM
My research aims to make so much synthetic gene regulatory data that we no longer need to train models on genomic sequences (elaborated on here www.nature.com/articles/s41...), but we still lack the needed synthetic data. hashFrag is the stopgap needed to enable genome-training without leakage.
Reposted by Nozomu Yachie
New (and hotly anticipated - at least by me) preprint from my group describing a better way to partition training data for genomic-trained models to solve the long-neglected problem of homology-based data leakage. Thread from first author @muntakimrafi.bsky.social 👇
0/ Essential reading for anyone training or using sequence-function models trained on genomic sequences! 🚨 In our new preprint, we explore the ways homology within genomes can cause leakage when training sequence-based models and ways to prevent it
January 27, 2025 at 11:48 PM
New (and hotly anticipated - at least by me) preprint from my group describing a better way to partition training data for genomic-trained models to solve the long-neglected problem of homology-based data leakage. Thread from first author @muntakimrafi.bsky.social 👇
We often perceive objects as units defined by the object that encompasses them. A topology question: does the plasma membrane of a cell enclose the cytoplasm and organelles, or does it encompass everything else, including Earth, while excluding the cytoplasmic region as its environment?
January 25, 2025 at 6:25 PM
We often perceive objects as units defined by the object that encompasses them. A topology question: does the plasma membrane of a cell enclose the cytoplasm and organelles, or does it encompass everything else, including Earth, while excluding the cytoplasmic region as its environment?
Reposted by Nozomu Yachie
