TJ Cradick @NucleaseLab
banner
nucleaselab.bsky.social
TJ Cradick @NucleaseLab
@nucleaselab.bsky.social
CRISPR Chief Technology Officer
Alum: @HuidaGene @ExcisionBio @CRISPRTx @GeorgiaTech @SangamoTx @UIowa @UCSF @MIT Posts = own.
Inaugural Genetic Agency Conference #GATC25 included many great sessions & talks, including 𝐕𝐢𝐜𝐭𝐨𝐫𝐢𝐚 𝐆𝐫𝐚𝐲 on her life with sickle cell disease, her groundbreaking Casgevy CRISPR treatment, and her subsequent journey as a patient advocate.

Powerful reminder of why this technology matters!
November 13, 2025 at 4:38 PM
Met many friends & colleagues at #ASHG2025, inc Andy McNamara & Yann Jouvenot, friends since Sangamo.
Also met people at ASHG that I worked with while at Repligen, Georgia Tech, Tularik, UCSF and CRISPR Therapeutics - so covered many years!
October 18, 2025 at 12:36 PM
If you are at #ASHG2025 and want to meet, please let me know.
#Boston Oct 14-18
Are there enough CRISPR / Gene Editing people for a meetup?
October 13, 2025 at 2:56 PM
This year, I am not joining colleagues at #CGMesa25 or #ESGCT2025, but here in Boston for 𝐅𝐢𝐞𝐫𝐜𝐞 𝐁𝐢𝐨𝐭𝐞𝐜𝐡 𝐖𝐞𝐞𝐤 #FBW2025.
Please let me know if you are also attending and want to meet up this week!
#CRISPR in #Boston
October 6, 2025 at 10:45 PM
@jtkantor.bsky.social Back at Fenway with the biotech group Bullpen.
Please rally us with the Pixies
September 17, 2025 at 12:04 AM
Hello @jtkantor.bsky.social
Please honor those Takin' Care Of Business for us today watching the Red Sox at Fenway on Labor Day
September 1, 2025 at 5:55 PM
The In-House Impact Biopharma Summit started today in Boston.
Today's sessions include Legal and Corporate Strategy & Financing.
August 27, 2025 at 3:21 PM
The Genome Engineering: CRISPR Frontiers meeting has started at #CSHL.
#cshlCRISPR25 #CRISPR
August 13, 2025 at 12:51 AM
Happy 𝗡𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗢𝘆𝘀𝘁𝗲𝗿 𝗗𝗮𝘆! Hopefully you are enjoying life on the Half Shell today in some form. Sharing International #Oyster photos, from Sylt, Paris and New Orleans (during #ASGCT2025).
August 5, 2025 at 10:13 PM
Happy #RNAday to everyone (in hopes you celebrate)

Hopefully AUG (the most common start codon) signals the start of a good month.
First of two RNA Editing presentations done, “Navigating RNA Editing Regulatory Challenges & Optimizing Translation of RNA Editing Candidates to Accelerate IND Approval” with Robert Deans.
Also shared slides/movies from Franz Gerner, Kate Excoffon and William Kennedy, MD.
August 2, 2025 at 2:18 AM
This afternoon concluded the 𝟔𝐭𝐡 𝐀𝐧𝐧𝐮𝐚𝐥 𝐑𝐍𝐀 𝐄𝐝𝐢𝐭𝐢𝐧𝐠 𝐒𝐮𝐦𝐦𝐢𝐭.
If you are not following the field, time to read up as things are moving fast.
I presented some early clinical data, with hopes that multiple companies would be presenting clinical updates in 2026 !
First of two RNA Editing presentations done, “Navigating RNA Editing Regulatory Challenges & Optimizing Translation of RNA Editing Candidates to Accelerate IND Approval” with Robert Deans.
Also shared slides/movies from Franz Gerner, Kate Excoffon and William Kennedy, MD.
July 31, 2025 at 10:39 PM
First of two RNA Editing presentations done, “Navigating RNA Editing Regulatory Challenges & Optimizing Translation of RNA Editing Candidates to Accelerate IND Approval” with Robert Deans.
Also shared slides/movies from Franz Gerner, Kate Excoffon and William Kennedy, MD.
July 29, 2025 at 8:25 PM
The 6th Annual RNA Editing Summit is kicking off today here in Boston.
July 29, 2025 at 1:43 PM
The @thesavbananas.bsky.social are in Fenway
Today 3:30pm !
Message me if interested in 2 extra tickets

@jtkantor.bsky.social will you be adding to the magic ?

www.youtube.com/watch?v=rMip...
How Banana Ball offers a different, fun take on baseball
YouTube video by PBS NewsHour
www.youtube.com
July 6, 2025 at 11:58 AM
Happy U.S. Independence Day.
July 4, 2025 at 11:05 PM
A Word / Excel tip: You can have 2 parts of the document on 2 monitors.
1) Under View Tab =>New Window
2) Drag new window to new monitor.
Note what Gemini gave for "biotech Lorem ipsum"
June 28, 2025 at 6:32 PM
This flyer for Biotech Tuesday caught my eye.
Back at Fabrica (where photo taken) – but I may be out of town
Link to Boston and Bay Area Biotech Tuesday Events
biotechtuesday.com/events
June 27, 2025 at 6:15 PM
First they condemned Calvin, then went after Hobbes

But seriously, book banners now looking at Calvin and Hobbes and many, many more acclaimed books, sometimes even without a review panel.
Another sign of the changing times.
How profoundly sad. The kids deprived of reading Calvin and Hobbes are the kids who need them the most. My brother put it best: "We know we’re fucked when they come for your cartoon stuffed tigers."

Let's go sit in the grass and crack open "The Days are Just Packed."
pen.org/magic-tree-h...
‘Magic Tree House’ Author, ‘Calvin and Hobbes’ among hundreds of Tennessee book bans - PEN America
The removals in Tennessee are the result of a growing political movement to control information through book banning.
pen.org
June 24, 2025 at 1:01 AM
Amazing to me that JAWS, the first summer blockbuster came out 50 years ago: June 20, 1975.

Travel tip: you can find many of the filming locations on #MarthasVineyard with a google map

m.youtube.com/watch?v=K2pT...
50 Years of JAWS
YouTube video by Channel Awesome
m.youtube.com
June 21, 2025 at 1:10 PM
Great to meet so many new people this week in #Boston through the many Bullpen and #BIO2025 events.

Excited to continue the discussions on #CRISPR Gene Editing with novel nucleases.
June 19, 2025 at 10:18 PM
@jtkantor.bsky.social The Biotech group, fittingly called the Bullpen is at #Fenway celebrating Monday’s #BIO2025 conference. Love the sun in bleachers, so please favor us: She Blinded UMe With Science
June 15, 2025 at 6:10 PM
At #BIO2025 this week! Please reach out to hear about our nucleases #hfCas12Max, RNA editors #hfCas13Y, #AI-guided base editors & #epigenetics,
or programs - spanning #CNS (#ALS, #MECP2 duplication syndrome, #Huntington's, #Alzheimer's), #DMD, and #ophthalmology (#Stargardt, #AMD, +)
June 15, 2025 at 12:42 PM
Thanks, I agree, this was nice to read after digesting the News
This is a fun Sunday morning read.
After the #spellingbee finals, check out this pronouncer’s-eye view in @defector.com?

defector.com/confessions-...
June 1, 2025 at 5:06 PM
I'd Hope & Dream to hear about venues having listening parties, or maybe as an intro to events!
May 22, 2025 at 1:11 AM