Nalle Pentinmikko
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Nalle Pentinmikko
@npentinmikko.bsky.social
Postdoctoral Fellow @ VincentLab
Reposted by Nalle Pentinmikko
I have a PhD student and an undergrad student positions open at the Institute of Biotechnology @helsinki.fi We are using reconstitution, cell and structural biology to study protein-membrane interactions and membrane microdomain formation. Links to calls below! Feel free to drop a message and share!
September 29, 2025 at 3:45 PM
Reposted by Nalle Pentinmikko
2 post-doc positions open in the lab to do research on inter-organ signalling in regeneration and cancer in flies and mice.
August 11, 2025 at 4:29 PM
Reposted by Nalle Pentinmikko
Proudly presenting Simon’s @simonsterson.bsky.social‬ paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
www.nature.com
July 14, 2025 at 10:21 AM
Reposted by Nalle Pentinmikko
Finishing the year with 1st preprint from the lab! Together with @katajistolab.bsky.social and @valerioizzi.bsky.social we investigated the role of basement membrane protein Lama5 and found it is critical for luminal breast cancer initiation and growth

www.biorxiv.org/content/10.1...
Tumour-derived LAMA5 is critical for tumour initiation and controls progression and phenotype in luminal breast cancer
Basement membrane (BM) supports and regulates the structural integrity, function and differentiation of epithelial tissues and protects against stromal invasion of breast cancer cells. Here we show th...
www.biorxiv.org
December 28, 2024 at 9:28 AM