Noëlle Warmenhoven
@noellewarmenhoven.bsky.social
PhD student at the Clinical Memory Research Unit, Lund University 🧠 | Fluid biomarkers for diagnosis of neurodegenerative diseases
Reposted by Noëlle Warmenhoven
New paper out in EMBO Mol Med! We use machine learning to predict Aβ-PET burden from fluid biomarkers. www.embopress.org/doi/full/10....
Key findings:
- Performance R² = 0.79
- CSF Aβ42/Aβ40 most predictive of Aβ plaque presence
- Plasma p-tau217 best for tracking increasing amyloid plaque burden
Key findings:
- Performance R² = 0.79
- CSF Aβ42/Aβ40 most predictive of Aβ plaque presence
- Plasma p-tau217 best for tracking increasing amyloid plaque burden
Prediction of continuous amyloid positron emission tomography with fluid measures of phosphorylated tau and β-amyloid | EMBO Molecular Medicine
imageimageMachine-learning models using CSF and plasma biomarkers accurately predicted quantitative
Aβ-PET burden. Distinct contributions of soluble Aβ42/Aβ40 and plasma P-tau217 reveal
their role in ...
www.embopress.org
December 2, 2025 at 12:13 PM
New paper out in EMBO Mol Med! We use machine learning to predict Aβ-PET burden from fluid biomarkers. www.embopress.org/doi/full/10....
Key findings:
- Performance R² = 0.79
- CSF Aβ42/Aβ40 most predictive of Aβ plaque presence
- Plasma p-tau217 best for tracking increasing amyloid plaque burden
Key findings:
- Performance R² = 0.79
- CSF Aβ42/Aβ40 most predictive of Aβ plaque presence
- Plasma p-tau217 best for tracking increasing amyloid plaque burden
Reposted by Noëlle Warmenhoven
🚨Postdoc position open at @BarcelonaBeta🚨
We're looking someone to work on a project at the intersection of cardiovascular and neurodegenerative research 🫀🧠
Fully funded position!!!
More details: www.imim.cat/media/upload...
Please share!
#Alzheimer's #ENDALZ
We're looking someone to work on a project at the intersection of cardiovascular and neurodegenerative research 🫀🧠
Fully funded position!!!
More details: www.imim.cat/media/upload...
Please share!
#Alzheimer's #ENDALZ
www.imim.cat
September 18, 2025 at 1:24 PM
🚨Postdoc position open at @BarcelonaBeta🚨
We're looking someone to work on a project at the intersection of cardiovascular and neurodegenerative research 🫀🧠
Fully funded position!!!
More details: www.imim.cat/media/upload...
Please share!
#Alzheimer's #ENDALZ
We're looking someone to work on a project at the intersection of cardiovascular and neurodegenerative research 🫀🧠
Fully funded position!!!
More details: www.imim.cat/media/upload...
Please share!
#Alzheimer's #ENDALZ
Reposted by Noëlle Warmenhoven
🚨Paper alert🚨
New publication in JAMA Neurology led by @gsalvado.bsky.social. In a multicentric study, we examined the clinical utility to assess preclinical #Alzheimer’s disease in cognitively unimpaired individuals.
jamanetwork.com/journals/jam...
A 🧵...
New publication in JAMA Neurology led by @gsalvado.bsky.social. In a multicentric study, we examined the clinical utility to assess preclinical #Alzheimer’s disease in cognitively unimpaired individuals.
jamanetwork.com/journals/jam...
A 🧵...
Plasma P-Tau217 to Identify Preclinical AD
This cohort study evaluates the use of plasma phosphorylated tau 217 in identifying preclinical Alzheimer disease in individuals with amyloid β pathology.
jamanetwork.com
September 16, 2025 at 7:15 AM
🚨Paper alert🚨
New publication in JAMA Neurology led by @gsalvado.bsky.social. In a multicentric study, we examined the clinical utility to assess preclinical #Alzheimer’s disease in cognitively unimpaired individuals.
jamanetwork.com/journals/jam...
A 🧵...
New publication in JAMA Neurology led by @gsalvado.bsky.social. In a multicentric study, we examined the clinical utility to assess preclinical #Alzheimer’s disease in cognitively unimpaired individuals.
jamanetwork.com/journals/jam...
A 🧵...
Reposted by Noëlle Warmenhoven
🚨New publication in Nature Medicine!
In this study, we demonstrate that a brief, self-administered cognitive test battery can reliably identify individuals with cognitive impairment in a primary care setting.
More details: linkedin.com/feed/update/...
Full paper: www.nature.com/articles/s41...
In this study, we demonstrate that a brief, self-administered cognitive test battery can reliably identify individuals with cognitive impairment in a primary care setting.
More details: linkedin.com/feed/update/...
Full paper: www.nature.com/articles/s41...
Primary care detection of Alzheimer’s disease using a self-administered digital cognitive test and blood biomarkers - Nature Medicine | The Swedish BioFINDER study
New publication in Nature Medicine!
In this study, led by PhD students Pontus Tideman and Linda Karlsson, we demonstrate that a brief, self-administered cognitive test battery can reliably identify ...
linkedin.com
September 15, 2025 at 1:23 PM
🚨New publication in Nature Medicine!
In this study, we demonstrate that a brief, self-administered cognitive test battery can reliably identify individuals with cognitive impairment in a primary care setting.
More details: linkedin.com/feed/update/...
Full paper: www.nature.com/articles/s41...
In this study, we demonstrate that a brief, self-administered cognitive test battery can reliably identify individuals with cognitive impairment in a primary care setting.
More details: linkedin.com/feed/update/...
Full paper: www.nature.com/articles/s41...
Reposted by Noëlle Warmenhoven
New paper published today in @nataging.nature.com !
This one took some time but it's always a pleasure working hand in hand with Laia Montoliu-Gaya and the Gothenburg team. Thanks also to the McGill group for also collaborating with TRIAD data.
A 🧵 below.
#ENDALZ
This one took some time but it's always a pleasure working hand in hand with Laia Montoliu-Gaya and the Gothenburg team. Thanks also to the McGill group for also collaborating with TRIAD data.
A 🧵 below.
#ENDALZ
🚨New publication in Nature Aging🚨
Co-led between Laia Montoliu-Gaya and @gsalvado.bsky.social.
We measured several tau peptides in blood and assess their different relationships with Alzheimer’s disease stages.
nature.com/articles/s43...
🧵
Co-led between Laia Montoliu-Gaya and @gsalvado.bsky.social.
We measured several tau peptides in blood and assess their different relationships with Alzheimer’s disease stages.
nature.com/articles/s43...
🧵
Plasma tau biomarkers for biological staging of Alzheimer’s disease - Nature Aging
Montoliu-Gaya, Salvadó et al. develop a blood-based model using tau biomarkers measured in a single analysis enabling biological staging of Alzheimer’s disease to support the diagnosis, prognosis and ...
nature.com
August 23, 2025 at 10:07 AM
New paper published today in @nataging.nature.com !
This one took some time but it's always a pleasure working hand in hand with Laia Montoliu-Gaya and the Gothenburg team. Thanks also to the McGill group for also collaborating with TRIAD data.
A 🧵 below.
#ENDALZ
This one took some time but it's always a pleasure working hand in hand with Laia Montoliu-Gaya and the Gothenburg team. Thanks also to the McGill group for also collaborating with TRIAD data.
A 🧵 below.
#ENDALZ
Very grateful to have had the opportunity to share our work comparing the FDA-approved p-tau217/AB42 blood test to CSF!
Super proud of @noellewarmenhoven.bsky.social !
She just nailed her first oral presentation at an international conference #AAIC2025🇨🇦
She just nailed her first oral presentation at an international conference #AAIC2025🇨🇦
July 31, 2025 at 12:48 AM
Very grateful to have had the opportunity to share our work comparing the FDA-approved p-tau217/AB42 blood test to CSF!
Reposted by Noëlle Warmenhoven
‼️NEW PREPRINT‼️
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
July 22, 2025 at 3:34 AM
‼️NEW PREPRINT‼️
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?
That's exactly what we do using AI in our new preprint!
Link: arxiv.org/abs/2507.13782
#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
Reposted by Noëlle Warmenhoven
New manuscript alert! Are plasma biomarkers🩸 predictive of Alzheimer’s disease progression in Down Syndrome (DS)? Our new study in collaboration with the ABC-DS consortium has now been published in @thelancetneuro.bsky.social: www.thelancet.com/journals/lan...
Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers: a longitudinal cohort study
Baseline and longitudinal plasma p-tau217 were associated with subsequent decline
in global cognition, progression to dementia, and increased tau burden, whereas baseline
p-tau217 and GFAP were associ...
www.thelancet.com
June 27, 2025 at 11:54 AM
New manuscript alert! Are plasma biomarkers🩸 predictive of Alzheimer’s disease progression in Down Syndrome (DS)? Our new study in collaboration with the ABC-DS consortium has now been published in @thelancetneuro.bsky.social: www.thelancet.com/journals/lan...
Reposted by Noëlle Warmenhoven
✨ REMINDER!! ✨ please help me gather the most inspiring papers of the last year (including your own!!) by completing the survey below! 🙏
Looking so much forward to presenting the @NeuroimagingPIA year in review talk at #AIC2025 in Toronto this July!! 🤩
alz.surveymonkey.com/r/923BTQK
Looking so much forward to presenting the @NeuroimagingPIA year in review talk at #AIC2025 in Toronto this July!! 🤩
alz.surveymonkey.com/r/923BTQK
So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠
🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK
🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK
🚨Calling all neuroimagers! Help
@emmacoomans.bsky.social shape the opening plenary at #AIC2025 (Toronto, July 26th) "Accomplishments of the Past Year" and share the most impactful neuroimaging research from the past year via this brief survey (~5min) by May 30th.
act.alz.org/site/R?i=eOe...
@emmacoomans.bsky.social shape the opening plenary at #AIC2025 (Toronto, July 26th) "Accomplishments of the Past Year" and share the most impactful neuroimaging research from the past year via this brief survey (~5min) by May 30th.
act.alz.org/site/R?i=eOe...
May 30, 2025 at 1:26 PM
✨ REMINDER!! ✨ please help me gather the most inspiring papers of the last year (including your own!!) by completing the survey below! 🙏
Looking so much forward to presenting the @NeuroimagingPIA year in review talk at #AIC2025 in Toronto this July!! 🤩
alz.surveymonkey.com/r/923BTQK
Looking so much forward to presenting the @NeuroimagingPIA year in review talk at #AIC2025 in Toronto this July!! 🤩
alz.surveymonkey.com/r/923BTQK
Reposted by Noëlle Warmenhoven
How does the brain reorganize in the context of age and AD?
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
May 27, 2025 at 1:53 PM
How does the brain reorganize in the context of age and AD?
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
Reposted by Noëlle Warmenhoven
🚨New paper in Alzheimer's & Dementia! We investigate whether p-tau immuno-assays selectively quantifying low-molecular-weight (LMW) tau (CNS) are more specific for tau changes in AD vs ALS than assays not differentiating between LMW and high-MW (PNS) tau👇https://pubmed.ncbi.nlm.nih.gov/40289884/
May 5, 2025 at 12:31 PM
🚨New paper in Alzheimer's & Dementia! We investigate whether p-tau immuno-assays selectively quantifying low-molecular-weight (LMW) tau (CNS) are more specific for tau changes in AD vs ALS than assays not differentiating between LMW and high-MW (PNS) tau👇https://pubmed.ncbi.nlm.nih.gov/40289884/
Reposted by Noëlle Warmenhoven
The preprint of my first PhD project is live! 🧠 Find the link to the manuscript and read about the key findings below. 👇 #alzheimersdisease #neuroimaging #tau #amyloid #mri #pet #biofinder
‼️New preprint!
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
April 25, 2025 at 9:48 AM
The preprint of my first PhD project is live! 🧠 Find the link to the manuscript and read about the key findings below. 👇 #alzheimersdisease #neuroimaging #tau #amyloid #mri #pet #biofinder
Reposted by Noëlle Warmenhoven
A new, simpler and cheaper analytical method for the early detection of #Alzheimers disease could help bring #blood tests into the #healthcare system globally, according to a new study co-authored by @noellewarmenhoven.bsky.social from 🇸🇪 @lund-university.bsky.social.
Simple, yet effective way to early detect Alzheimer's disease
A simpler method of analysing blood samples for Alzheimer’s disease has been tested in a large multicentre study, led by Lund University in Sweden.
healthcare-in-europe.com
April 17, 2025 at 6:32 AM
A new, simpler and cheaper analytical method for the early detection of #Alzheimers disease could help bring #blood tests into the #healthcare system globally, according to a new study co-authored by @noellewarmenhoven.bsky.social from 🇸🇪 @lund-university.bsky.social.
Reposted by Noëlle Warmenhoven
New manuscript alert! Can blood-based biomarkers measured on a fully automated platform accurately identify Alzheimer’s disease (AD) pathology?🩸 Our new multi-cohort study has now been published in
@naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵
@naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵
Plasma phospho-tau217 for Alzheimer’s disease diagnosis in primary and secondary care using a fully automated platform - Nature Medicine
Among 1,767 patients in 5 centers, a fully automated blood test showed high accuracy for Alzheimer’s pathology in secondary and primary care using a predefined cutoff.
nature.com
April 9, 2025 at 12:37 PM
New manuscript alert! Can blood-based biomarkers measured on a fully automated platform accurately identify Alzheimer’s disease (AD) pathology?🩸 Our new multi-cohort study has now been published in
@naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵
@naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵
Reposted by Noëlle Warmenhoven
‼️New publication on a novel plasma biomarker for tau pathology 🧠🧪 in @naturemedicine.bsky.social led by Kanta Horie & @gsalvado.bsky.social:
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 2:44 PM
‼️New publication on a novel plasma biomarker for tau pathology 🧠🧪 in @naturemedicine.bsky.social led by Kanta Horie & @gsalvado.bsky.social:
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
Reposted by Noëlle Warmenhoven
