Rapid progress in artificial intelligence (AI) capabilities has drawn fresh attention to the prospect of consciousness in AI. There is an urgent need …

AbstractBackground and Aims. Angina with non-obstructive coronary arteries (ANOCA) is a prevalent myocardial ischaemic syndrome, and women are disproportio

Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis that confers increased risk of atherosclerotic cardiovascular disease. Measured by noncontrast cardiac computed tomography, CAC...

Obesity is a core pathophysiologic contributor to cardiovascular, kidney, and metabolic (CKM) conditions. However, the association between different a…

Archaeological and Anthropological Sciences - The Upper Palaeolithic (UP) of westernmost Europe was marked by technological and cultural transformations and abrupt climatic shifts. The Iberian...

Toker and Monti report that rare causes of disorders of consciousness—including infections, autoimmune conditions, genetic disorders, and neurodegenerative

Abstract. Since the 1950s, when Ancel Keys popularized the traditional Mediterranean diet, an immense accrual of large and valid studies, including prospec

Scientists used molecular simulations to reveal how polymer chains adhere to alumina surfaces. Adhesion depends on both polymer chemistry and surface termination, with different responses before and a...

Evolutionary Cognitive Archaeology and Acheulean Technology. A Historiographic Review - Volume 35 Issue 4

To celebrate over 55 years of Physics of the Earth and Planetary Interiors providing a venue for communicating advancements in the chemical and dynami…

Stabilizers/silencers limit new transthyretin amyloid formation, while emerging agents aim to clear existing deposits. Cardiovascular magnetic resonan…

Alzheimer’s disease (AD) is a debilitating disorder marked by progressive memory and cognitive function loss. Current treatments, including acetylcholinesterase and N-methyl-d-aspartate receptor inhib...

Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non-invasive biomarkers. By reviewing and criti...

Hyperkalemia is common with RASi therapy, frequently leading to treatment interruption and potentially curtailing cardiovascular and kidney benefits. …

BACKGROUND: Proteins linked to heritable coronary heart disease (CHD) could uncover new pathophysiological mechanisms of atherosclerosis. We report on the protein profile associated with a family hist...

ObjectivesThe aim of this study was to investigate the endophenotypic potential of striatal dopamine transporter (DAT) uptake in carriers of Parkinson disease (PD)–associated SNCA genetic risk variant...

Organized cell architecture and dynamic forces are key for (re)creating native-like tissue function (e.g., contractile soft tissues). However, few stu…

Alzheimer’s disease (AD) is a chronic multifactorial neurodegenerative disease affecting a large proportion of the elderly population with detrimental psychological and socioeconomic impacts. This review starts with a brief overview of the molecular aspects of AD. It aims to provide recent updates on several potential protein targets studied as valid therapeutic approaches such as Bassoon protein, triggering receptor expressed on myeloid cells 2 (TREM2), phosphorylated tau (chimeric molecules...

A mechanism describing how NAD+ regulates alternative RNA splicing to inhibit Alzheimer’s disease is unveiled.

Dynamic laser micromachining enables versatile bioelectronic devices with 3D features and advanced functionality.

Gao et al. report a series of oral microbial signatures associated with EC risk and illustrate the interplay between poor oral health and the oral microbiome in relation to EC. Microbiome-targeted str...